Medicine and Health Sciences Commons^™

Group Cohesion And Homework Adherence In Multi-Family Group Therapy For Schizophrenia, Frank P. Deane, Joanne Mercer, Anahita Talyarkhan, Gordon Lambert, Judy Pickard

Faculty of Health and Behavioural Sciences - Papers (Archive)

This study examined the relationship between levels of group cohesion, defined as whole group relationships, and between-session therapeutic homework adherence in a multi-family group therapy (MFGT) for people with schizophrenia. Participants from 18 consenting families attending MFGT groups completed weekly homework adherence ratings, group cohesion and spontaneous between-session activity measures. Levels of group cohesion at each session were compared with measures of scheduled and spontaneous homework adherence reported at the next session. It was hypothesised that higher levels of group cohesion would be related to homework adherence and other spontaneous between-session therapeutic activity completed by group members. Results show higher …

The Impact Of Cannabis Use On Cognitive Functioning In Patients With Schizophrenia: A Meta-Analysis Of Existing Findings And New Data In A First-Episode Sample, Murat Yücel, Emre Bora, Daniel I. Lubman, Nadia Solowij, Warrick J. Brewer, Sue M. Cotton, Phillipe Conus, Michael J. Takagi, Alex Fornito, Stephen J. Wood, Patrick D. Mcgorry, Christos Pantelis

Faculty of Health and Behavioural Sciences - Papers (Archive)

Cannabis use is highly prevalent among people with schizophrenia, and coupled with impaired cognition, is thought to heighten the risk of illness onset. However, while heavy cannabis use has been associated with cognitive deficits in long-term users, studies among patients with schizophrenia have been contradictory. This article consists of 2 studies. In Study I, a meta-analysis of 10 studies comprising 572 patients with established schizophrenia (with and without comorbid cannabis use) was conducted. Patients with a history of cannabis use were found to have superior neuropsychological functioning. This finding was largely driven by studies that included patients with a lifetime …

The Schizophrenia Susceptibility Gene Neuregulin 1 Modulates Tolerance To The Effects Of Canabinoids, Aurelie Boucher, Glenn E. Hunt, Jacques Micheau, Xu-Feng Huang, Iain Mcgregor, Tim Karl, Jonathon Arnold

Faculty of Health and Behavioural Sciences - Papers (Archive)

Cannabis increases the risk of schizophrenia in genetically vulnerable individuals. In this study we aim to show that the schizophrenia susceptibility gene neuregulin 1 (Nrg1) modulates the development of tolerance to cannabinoids in mice. Nrg1 heterozygous (HET) and wild-type (WT) mice were treated daily for 15 d with the synthetic analogue of D9-tetrahydrocannabinol, CP55,940 (0.4 mg/kg). We measured the impact of this exposure on locomotor activity, anxiety, prepulse inhibition (PPI), body temperature and FosB/DFosB immunohistochemistry. Tolerance to CP55,940-induced hypothermia and locomotor suppression developed more rapidly in Nrg1 HET mice than WT mice. Conversely in the light-dark test, while tolerance to …

Cerebellar White-Matter Changes In Cannabis Users With And Without Schizophrenia, N Solowij, M Yucel, C Respondek, S Whittle, E Lindsay, C Pantelis, D I. Lubman

Faculty of Health and Behavioural Sciences - Papers (Archive)

Background. The cerebellum is rich in cannabinoid receptors and implicated in the neuropathology of schizophrenia. Long-term cannabis use is associated with functional and structural brain changes similar to those evident in schizophrenia, yet its impact on cerebellar structure has not been determined. We examined cerebellar grey and white matter in cannabis users with and without schizophrenia. Method. Seventeen patients with schizophrenia and 31 healthy controls were recruited ; 48% of the healthy group and 47% of the patients were long-term heavy cannabis users (mean 19.7 and 17.9 years near daily use respectively). Cerebellar measures were extracted from structural 3-T magnetic …

Quality Of Life Among People With Schizophrenia In Saudi Arabia, Amira Ali Alshowkan, Janette Curtis, Yvonne White

Faculty of Health and Behavioural Sciences - Papers (Archive)

Research aims: To provide a profile of the quality of life of people with schizophrenia in Saudi Arabia. To investigate the relationships between Socio-demographic characteristics and their quality of life.

The Quality Of Life Of People With Schizophrenia Living In The Community In Al-Khobar, Saudi Arabia, Amira Ali Alshowkan, Janette Curtis, Yvonne White

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.

Immune Factors In The Neuregulin-1 Knockout Mouse Model Of Schizophrenia, P Snikeris, Xu-Feng Huang, Elisabeth T. Frank

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.

Decreased Density Of Serotonin 2a Receptors In The Superior Temporal Gyrus In Schizophrenia - A Postmortem Study, Xu-Feng Huang, Chao Deng, Qing Wang, Kai Kang

Faculty of Health and Behavioural Sciences - Papers (Archive)

The superior temporal gyrus (STG) is strongly implicated in the pathophysiology of schizophrenia,particularly with regards to auditory hallucinations. In this study, using in situ quantitative autoradiography in postmortem tissue, we investigated the binding of the [3H]ketanserin to 5-HT2A receptors and [3H] mesulergine to 5-HT2C receptors in the left STG of 8 male schizophrenic patients compared to 8 control subjects. A strong [3H]ketanserin binding was observed in the STG, however there was a very weak [3H] mesulergine binding in the STG. A significant decrease in binding of [3H]ketanserin was clearly observed in schizophrenia patients in comparison with control subjects. There were …

The Saint Of Worcester: Why Pilgrims Visit Audrey Santo, Mathew N. Schmalz

Religious Studies Faculty Scholarship

No abstract provided.

Schizophrenia, Fats And Lab Rats, Teresa M. Du Bois

Faculty of Health and Behavioural Sciences - Papers (Archive)

No abstract provided.

Changing Staff Attitudes And Empathy For Working With People With Psychosis, H. J. Mcleod, F. P. Deane, B. Hogbin

Faculty of Health and Behavioural Sciences - Papers (Archive)

Seventy-seven mental health professionals completed a 3-day cognitive behavioural training course for managing hallucinations and delusions in schizophrenia. A questionnaire measuring attitudes and empathy towards working with people who have these symptoms was administered before and after the course. Significant increases in feelings of adequacy, legitimacy, employment related self-esteem, and expectations of work satisfaction were observed after the course and participants displayed high levels of motivation for working with this clinical population at both time points. In addition, the participants showed significant increases in perceived empathy for the experience of hallucinations and delusions. This was a predicted outcome as the …

Ariel - Volume 6 Number 2, Jim Burke, Halley S. Faust, J.D. Kanofsky, Sandy Wolf, Janet Bernstein, Liz Thile, Mike Treat, Tim Heffron, Robert Brent, Gary Kaskey, Curt Cummings, Paul Poinsard, Gary Emmett

Ariel

Editors

Mark Dembert

J.D. Kanofsky

Frank Chervenak

John Lammie

Curt Cummings

Entertainment

Robert Breckenridge

Joe Conti

Gary Kaskey

Photographer

Larry Glazerman

Overseas Editor

Mike Sinason

Humorist

Jim McCann

Staff

Ken Jaffe

Bob Skarloff

Halley Faust

Jim Burke

Ariel - Volume 5 Number 5, Philip Nimoityn, J.D. Kanofsky, Bob Sklaroff, Morton A. Klein, David A. Jacoby, Elaine T. Carville, Robert L. Brent, Janet Welsh, Gary Kaskey, Steve Glinka

Ariel

Editors

Mark Dembert

J. D. Kanofsky

Entertainment

Robert Breckenridge

Joe Conti

Gary Kaskey

Photographer

Scot Kastner

Overseas Editor

Mike Sinason

Circulation

Jay Amsterdam

Humorist

Jim McCann

Staff

Ken Jaffe

Bob Sklaroff

Janet Welsh

Dave Jacoby

Phil Nimoityn

Frank Chervanek