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Irritable Bowel Syndrome: Proposed Mechanisms Of Pathophysiology And The Underlying Dysregulation Of Brain-Gut Interaction, Hailey Haddix May 2023

Irritable Bowel Syndrome: Proposed Mechanisms Of Pathophysiology And The Underlying Dysregulation Of Brain-Gut Interaction, Hailey Haddix

Senior Honors Theses

Irritable bowel syndrome (IBS) is a disease of the gastrointestinal tract affecting approximately 11-21% of people worldwide (Xiao et al., 2021). This research focuses on the dysregulation of gut homeostasis in IBS and explains how the pathophysiology of the gut is controlled by the bidirectional brain-gut axis. The mechanisms of the brain-gut axis consist of neuro-immune cross talk, neuro-hormone cross talk, microbiome-gut signaling, and the HPA-axis. Each of these contribute to one or more of the possible phenotypes of gut pathophysiology, which could include intestinal permeability, visceral hypersensitivity, and motility disturbance (Xiao et al., 2021). Stress is also an important …


Tight Trip Vs. Loose Grip On Russian Kettlebell Swing Work Capacity, Austin Deshner, Abigail Mccarty, Jerrell C. Campbell, Andrew Fields, Will W. Peveler May 2021

Tight Trip Vs. Loose Grip On Russian Kettlebell Swing Work Capacity, Austin Deshner, Abigail Mccarty, Jerrell C. Campbell, Andrew Fields, Will W. Peveler

Masters Theses

The purpose of this study was to examine the effects of a tight grip(TG) and a loose grip(LG) on work capacity while performing Russian kettlebell swings(KBS). It was hypothesized that LG would result in an ability to perform more work. Thirty fit adults (16 male; 14 female) were tested. Two (TG and LG) separate counterbalanced trials for each subject were collected, counting the number of repetitions completed until volitional exhaustion. RPE for forearms and overall exhaustion were collected post-trial. SPSS was used to run a paired samples t-test. There was a significant difference between the two grips (p = 0.013)(TG …