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Magnetic Drug Delivery Of Xanthohumol To Adipocytes Using Ultrasmall Superparamagnetic Iron Oxide Nanoparticles., Irandokht Khaki Najafabadi, Janaiya Samuels, Royce Dansby-Sparks, Srujana Rayalam, Vicky Mody
Magnetic Drug Delivery Of Xanthohumol To Adipocytes Using Ultrasmall Superparamagnetic Iron Oxide Nanoparticles., Irandokht Khaki Najafabadi, Janaiya Samuels, Royce Dansby-Sparks, Srujana Rayalam, Vicky Mody
Research Day
According to the CDC’s National Center for Health Statistics, more than one-third (36.5%) of U.S adults are obese. It is the main risk factor for type-2-diabetes, hypertension, dyslipidemia and atherosclerosis. Nutraceuticals such as Xanthohumol have shown potential to inhibit adipogeneis, however, their bioavailability has remained controversial. Hence there is a need to develop targeted therapy which will increase the concentration of Xanthohumol on adipose tissues. Currently, magnetic drug delivery has been used to develop targeted therapies where conventional therapies have proven to be less effective. Among various types of nanoparticles ultrasmall superparamagnetic iron oxide nanoparticles (USPIO) have found considerable attention …