Medicine and Health Sciences Commons^™

Joint Effect Of Genetic And Lifestyle Risk Factors On Type 2 Diabetes Risk Among Chinese Men And Women, Raquel Villegas, Ryan Delahanty, Yu-Tang Gao, Jirong Long, Scott M. Williams, Yong-Bing Xiang, Hui Cai, Hong-Lan Li, Frank Hu, Qiuyin Cai, Wei Zheng, Xiao-Ou Shu

Dartmouth Scholarship

More than 40 genetic susceptibility loci have been reported for type 2 diabetes (T2D). Recently, the combined effect of genetic variants has been investigated by calculating a genetic risk score. We evaluated 36 genome-wide association study (GWAS) identified SNPs in 2,679 T2D cases and 3322 controls in middle-age Han Chinese. Fourteen SNPs were significantly associated with T2D in analysis adjusted for age, sex and BMI. We calculated two genetic risk scores (GRS) (GRS1 with all the 36 SNPs and GRS2 with the 14 SNPs significantly associated with T2D). The odds ratio for T2D with each GRS point (per risk allele) …

Titcomb, John M., B. 1814? (Sc 756), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and scan (Click on "Additional Files" below) for Manuscripts Small Collection 756. Medical remedies and recipes collected in a small notebook of John M. Titcomb of Baltimore, Maryland.

Mid-Atlantic Ethics Committee Newsletter, Fall 2012

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Coronary Heart Disease In Primary Care: Accuracy Of Medical History And Physical Findings In Patients With Chest Pain – A Study Protocol For A Systematic Review With Individual Patient Data, Jörg Haasenritter, Marc Aerts, Stefan Bösner, Frank Buntinx, Bernard Burnand, Lilli Herzig, J André Knottnerus, Girma Minalu, Staffan Nilsson, Walter Renier, Carol Sox, Carol Sox, Harold Sox, Norbert Donner-Banzhoff

Dartmouth Scholarship

Chest pain is a common complaint in primary care, with coronary heart disease (CHD) being the most concerning of many potential causes. Systematic reviews on the sensitivity and specificity of symptoms and signs summarize the evidence about which of them are most useful in making a diagnosis. Previous meta-analyses are dominated by studies of patients referred to specialists. Moreover, as the analysis is typically based on study-level data, the statistical analyses in these reviews are limited while meta-analyses based on individual patient data can provide additional information. Our patient-level meta-analysis has three unique aims. First, we strive to determine the …

Are Maternal Child Health Outcomes Affected By Adequacy Of Prenatal Care In Montgomery County, Oh?, Amy Rouse

Master of Public Health Program Student Publications

Background: Prenatal Care has been recommended by the World Health Organization for all pregnant women in order to improve health outcomes of the mother and the child. However, recommendations for the number of visits required to provide adequate health care and improve outcomes continue to be debated. Understanding if adequate prenatal care is improving maternal child outcomes is essential before making these recommendations. This research aims to determine if in Montgomery County, OH the adequacy of prenatal care influenced gestational age at birth, birth weight, breastfeeding rate, rate of cesarean sections, and smoking cessation rates.

Methods: De-indentified birth data was …

Refining The Global Spatial Limits Of Dengue Virus Transmission By Evidence-Based Consensus, Oliver J. Brady, Peter W. Gething, Samir Bhatt, Jane P. Messina, John S. Brownstein, Anne G. Hoen

Dartmouth Scholarship

Background: Dengue is a growing problem both in its geographical spread and in its intensity, and yet current global distribution remains highly uncertain. Challenges in diagnosis and diagnostic methods as well as highly variable national health systems mean no single data source can reliably estimate the distribution of this disease. As such, there is a lack of agreement on national dengue status among international health organisations. Here we bring together all available information on dengue occurrence using a novel approach to produce an evidence consensus map of the disease range that highlights nations with an uncertain dengue status.

Methods/Principle Findings: …

Evaluating The Effectiveness Of The Blood Pressure Plus Program At Thomas Jefferson University, Adam C. Winters

Department of Family & Community Medicine Faculty Papers

Thomas Jefferson University Hospital’s Blood Pressure Plus program enhances the role of the community in chronic disease prevention and management. There is much evidence that controlling disease and cost is greatly improved through the involvement of community leaders and resources. By offering free blood pressure screenings, the BP+ program was able to document the current status of many underserved individuals in the city of Philadelphia, provide the necessary education and referrals. Perhaps more importantly, the program allowed us to foster relationships with individuals who could further the efforts of chronic care management within their communities. More and more we’re seeing …

Schickel, Joseph Herman, 1913-1992 (Mss 416), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Collection 416. This collection contains Dr. Joseph Schickel’s personal papers and files. The majority of the collection regards Dr. Schickel’s medical practice in Burkesville, Kentucky, and his extensive community work throughout Cumberland County, Kentucky.

Murphey, G. N. (Sc 441), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and full-text scan (Click on "Additional Files" below) for Manuscripts Small Collection 441. Copy of application, Bowling Green, Kentucky, for a license to practice medicine in Kentucky.

Mcdowell, Ephraim, 1771-1830 - Relating To (Sc 2551), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 2551. First day of issue cover for stamp celebrating the 150th anniversary of the first successful ovariotomy, performed by Ephraim McDowell. Includes a brief printed history of the surgery, as well as a printed letter from the Danville, Kentucky Chamber of Commerce announcing the commemorative stamp.

Food Deserts And Their Association With Obesity And Diabetes In Ohio, Alexis Holmes, Detra Thompson

Master of Public Health Program Student Publications

Objective- The purpose of this study was to explore the association of food access, and availability, on prevalence of diabetes and obesity in Ohio census tracts designated as food deserts.

Methods- County and census tract-level data were combined from the USDA Food Environment Atlas and USDA Food Desert Locator respectively. Statistical analysis was conducted using IBM Statistical Package for Social Sciences (SPSS). Non-normally distributed variables were assessed using the Mann-Whitney nonparametric U-test and Spearman’s correlation coefficient. Significance was considered at the p

Results- The mean rate of obesity and diabetes in Ohio in food deserts are 29.5% and 10.7%, when …

Halcomb, Warren G. (Sc 587), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and scan (Click on "additional files" below) for Manuscripts Small Collection 587. Ciphering book of Warren G. Halcomb’s of Caswell County, North Carolina, which he kept from 11 September 1809 to 15 July 1815. Other entries in the book include a few family names and dates, personal business notes, and a recipe for the cure of rheumatism. Loose items, 1840-1854, found in the book concern the slave trade, 1840 and 1849.

Chism Family Papers (Sc 603), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and scans including slave items (Click on "additional files" below) for Manuscripts Small Collection 603. Chiefly business papers of the Chism family of Monroe County, Kentucky, with most of the papers being those of J. T. Chism (1810-1884). Includes slave items, 1808, 1856 (2); letters pertaining to the pork industry and trade, 1867-1880 (36); doctor’s letters containing medical instructions for patient and prescriptions, 1863-1864 (4); receipts for goods sold to Union forces, 1863-1864 (8); and miscellaneous items.

Lewis, John Alexander, B. 1841 (Sc 520), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and scan (Click on "additional files" below) for Manuscripts Small Collection 520. Printed pamphlets and typescripts, one with holographic corrections, or speeches and papers read before the Kentucky State Medical Association and the Kentucky State Medical Society by John Alexander Lewis, a physician of Georgetown, Scott County, Kentucky.

Lloyd, John Uri, 1849-1936 (Sc 458), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid and scan (Click on "additional files" below) for Manuscripts Small Collection 458. Letter written by John Uri Lloyd, Cincinnati, Ohio, to John Stuart Groves, Wilmington, Delaware, regarding Lloyd’s writings about certain diseases.

Med5(Nut1) And Med17(Srb4) Are Direct Targets Of Mediator Histone H4 Tail Interactions, Zhongle Liu, Lawrence C. Myers

Dartmouth Scholarship

The Mediator complex transmits activation signals from DNA bound transcription factors to the core transcription machinery. In addition to its canonical role in transcriptional activation, recent studies have demonstrated that S. cerevisiae Mediator can interact directly with nucleosomes, and their histone tails. Mutations in Mediator subunits have shown that Mediator and certain chromatin structures mutually impact each other structurally and functionally in vivo. We have taken a UV photo cross-linking approach to further delineate the molecular basis of Mediator chromatin interactions and help determine whether the impact of certain Mediator mutants on chromatin is direct. Specifically, by using histone …

Fostering Aging In Place: "Healthy Naturally Occurring Retirement Community" (H-Norc) Qualities In A Southwest Ohio Suburb, Laura A. Previll

Master of Public Health Program Student Publications

This community assessment uses the concept of “H-NORCs” or Healthy Naturally Occurring Retirement Communities as a framework to analyze supports for aging (Masotti, Johnson-Masotti, Fick, & MacLeod, 2006) in Kettering, Ohio -- a first tier suburb of Dayton where the proportion of people over the age of 60 was 23.8% in 2010. In this study, I used focus groups and interviews to collect qualitative data on five H-NORC attributes: (1) economic policies that benefit seniors; (2) types of transportation support for seniors; (3) neighborhood design for physical activity; (4) opportunities for social integration and sense of belonging; and (5) health …

Metabolomics: The Final Frontier?, Timothy D. Veenstra

Pharmaceutical Sciences Faculty Publications

No abstract provided.

Bowling Green Warren County Medical Society Alliance, 1952-2011 (Mss 402), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Collection 402. Organizational materials including constitution, by-laws, membership directories and scholarship files for the Bowling Green Warren County Medical Society Alliance of Bowling Green, Kentucky. The bulk of the collection relates to the two Western Kentucky University nursing scholarships granted by the group: the Newman & Lena Harris Scholarship and the Maydelle Johnson Funk Scholarship.

Louisville Medical School - Louisville, Kentucky - Notes (Sc 321), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 321. Notebook kept by an unidentified student at the Louisville (Kentucky) Medical School. Includes notes of lectures given by professors Yandell, Miller, Gross, Palmer, Rogers, Flint and Smith.

Mid-Atlantic Ethics Committee Newsletter, Spring 2012

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Differences In Immunity Offered By The Influenza Vaccination Among Active Duty Us Air Force Personnel From 2007-2011, Billy D. Pruett

Master of Public Health Program Student Publications

OBJECTIVE: To investigate the potential difference in vaccine effectiveness among Active Duty Air Force (ADAF) personnel vaccinated against influenza from 2007-2011. Particularly, to determine if any difference in the protection offered is based on sex, vaccine type, or both.

METHODS: The proposed study incorporated a cross-sectional design using the Department of Defense’s (DoD) comprehensive databases. Laboratory-confirmed influenza and other Influenza-Like Illness (ILI) cases were identified for each of the four influenza seasons of interest, vaccination status and history was then verified, and 2x2 tables were constructed in order to calculate odds ratios.

RESULTS: No consistent difference in vaccine effectiveness in …

Rights Of Ohio Mothers: Best Practices For The Pediatric Patient With A Life-Threatening Illness, Kelly Peekstok

Master of Public Health Program Student Publications

The purpose of this paper is to evaluate and review current best practices with regards to a minor’s refusal of life-sustaining medical treatment. The policies of other developed countries and states within the United States serve as a guide for developing evidence-based guidelines for Ohio healthcare professionals. Four specific cases were identified and then analyzed. The results showed that in three of the four cases, the wishes of the minor were followed. While each case contains its own set of complexities, creating a developmental guideline for healthcare organizations will ensure protection of the minor’s capacity to make autonomous decisions.

Evidence-Based Hazmat Medical Surveillance, Michael D. Jacobson

Master of Public Health Program Student Publications

Background: Hazardous materials (HAZMAT) teams are tasked with neutralizing substances that pose a dire threat to human health. As a result, communities invest substantially in medical surveillance to protect first responders. Yet, little is known as to the actual exposures, consequent injuries, and cost-effectiveness of medical surveillance.

Objective: The purposes of this study were: 1) Determine actual HAZMAT threats. 2) In light of these threats, evaluate current regulatory requirements, recommendations and practices for their basis in evidence.

Methods: National HAZMAT data was analyzed for trends and compared with local response records from 2008 through 2011. Regulations applicable to medical surveillance …

A Descriptive Analysis Of Lung Cancer In Montgomery County, Ohio, Catherine Klose

Master of Public Health Program Student Publications

Background: Lung cancer statistics are alarming, especially when it is considered by many to largely be a preventable disease. Lung cancers are the leading cause of all cancer deaths, more than breast cancer, prostate cancer, and colon cancer combined. Cancers of the bronchus and lung make up the greatest percentage of the newly diagnosed cancers reported to the Ohio Cancer Incidence Surveillance System (OCISS). The stage of diagnosis of lung and bronchus cancers is an important determinant of survival. Smoking is the primary cause of lung cancer. Race and gender disparities also exist with lung cancer, and socioeconomic factors have …

Analyzing Healthy Lifestyle Initiatives For Seniors: A Descriptive Study Of Senior Centers In Montgomery County, Ohio, Abhinav Rajpal

Master of Public Health Program Student Publications

The population of the elderly is expected to rise due to an increase in life expectancy and the aging baby boomer population. This increase in the elderly population will likely cause a burden on the health care system. This burden can be mitigated by promoting healthy lifestyles such as increased physical activity, healthy eating, and tobacco cessation in the elderly. Additionally, by participating in healthy behaviors, seniors can significantly improve their quality of life. Senior centers are at the forefront of promoting healthy lifestyles for the elderly. By promoting physical, social, and mental well-being, senior centers act as a focal …

Analysis Of An Improved Cook Stove Intervention In Rural Guatemala, Chad Graven

Master of Public Health Program Student Publications

An estimated three billion people cook and heat their homes using open fires and nearly two million people die prematurely from illness attributable to indoor air pollution from solid fuel use. According to the World Health Organization, “every year, indoor air pollution is responsible for the death of 1.6 million people...one death every twenty seconds.” Various international groups, government initiatives, and communities have attempted to improve this indoor air pollution problem around the world by implementing various improved cook stove models. In July, 2011, Partners In Health (PIH) and Equipo Técnico de Educación en Salud Comunitaria (ETESC) co-directed the delivery …

Chronic Disease Prevalence Of A Refugee Population In Dayton, Oh, Sandeep Palakodeti

Master of Public Health Program Student Publications

Introduction: This study aimed to understand the chronic disease burden of anemia, cancer, diabetes mellitus, hypertension, overweight/obesity, stroke, and tobacco use in the domestic as well as a refugee population. It also aimed to examine the current literature on appropriate screening for those conditions.

Methods: 348 refugee screening intake exams from Public Health - Dayton & Montgomery County were analyzed for presence of the conditions stated. Screening intake recommendations from the CDC, the Minnesota Public Health Department, the Canadian Collaboration for Immigrant and Refugee Health, and the Ohio Department of Job and Family Services were examined and compared in order …

Health Enhancing Policies And Environments In Select Montgomery County Senior Centers, Stacey L. Gardner

Master of Public Health Program Student Publications

As the baby boomer generation reaches elderly status, healthcare expenditures in the United States continue to rise. Contributing to healthcare costs is the high prevalence of chronic diseases caused by unhealthy habits of Americans such as tobacco use, lack of physical activity, and consumption of a poor diet. Many chronic diseases can be prevented by engaging in healthier behaviors. Communities and organizations can shift social norms and affect behaviors through policy intervention and environmental strategies. The purpose of this study was to describe policies and environments that foster healthy lifestyles in select senior centers in Montgomery County, Ohio. Specifically, this …

Polymers Used In Medicine: Common Types And Benefits Of Drug Delivery Systems, Camille Andrews

Natural Sciences Student Research Presentations

This poster describes the common types and benefits of drug delivery systems.