Medicine and Health Sciences Commons^™

Case Presentation On Urinary Bladder Cancer And Cysto-Prostatectomy, Tetiana Soloviova

Publications and Research

Patients who have invasive bladder cancer (spread to different tissues and organs) may need to have a radical cystectomy type of surgery. In male patients, the surgeon usually removes the prostate and seminal vesicles in addition to the bladder, parts of the ureters, and lymph nodes (Nicholson, 2017, ¶ 1)

In our case a reconstructive surgery followed right after removing of the bladder and prostate gland. A different way of urine to be stored and passed from the patient’s body was created by the surgeon. A part of small intestine was used to make up a reservoir that will serve …

Determining The Effects Of Cancer Mutations On The Coactivator Function Of The P300 Core Domain In Human Cells, Katlyn Myers, Erin Shanle, Meagan St. John

Selected Publications

In human cells, DNA is packed into chromosomes by wrapping around proteins called histones. Histone proteins contain chains of amino acids called histone tails and can be modified by acetylation. Acetylating histone proteins is important to the cell because it opens up the chromatin and allows for gene expression. Proteins can recognize and bind histone acetylation with a region called a bromodomain. p300 is a bromodomain-containing protein with histone acetyltransferase activity (HAT) which also aids with gene expression and is a coactivator protein of transcription. The bromodomain and HAT domain of this protein is considered the p300 core. Previous research …

Nanomedicine, Mark Tuominen

Nanotechnology Teacher Summer Institutes

An overview of nanomedicine. The end goal of nanomedicine is improved diagnostics, treatment and prevention of disease. Nanotechnology holds key to a number of recent and future breakthroughs in medicine.