Medicine and Health Sciences Commons^™

Hiv-Seropositive Patients’ Experiences With Social Workers: A South African Hiv+ Social Worker’S Reflective Log, Delarise Maud Mulqueeny

The Qualitative Report

Social workers play a pivotal role in HIV-seropositive patients’ treatment and care within South African public antiretroviral treatment (ART) programs. This article is a reflective log of an HIV-seropositive social worker’s observations and reflections on her positionality during a study on HIV-seropositive patients’ experiences of the public ART program in eThekwini, KwaZulu-Natal, South Africa. The primary investigator (PI) utilized various tools and techniques including reflexive bracketing, participatory action research and a reflexive diary to navigate a sensitive study. This was while being cognizant of the fluidity of her insider/outsider positionality. The disclosure of the PI’s HIV-seropositive status culminated in all …

Gwatch: A Web Platform For Automated Gene Association Discovery Analysis, Anton Svitin, Sergey Malov, Nikolay Cherkasov, Paul Geerts, Mikhail Rotkevich, Pavel Dobrynin, Andrey Shevchenko, Li Guan, Jennifer L. Troyer, Sher L. Hendrickson, Holli Hutcheson Dilks, T. K. Oleksyk, Sharyne Donfield, Edward Gomperts, Douglas A. Jabs, Efe Sezgin, Mark Van Natta, P. Richard Harrigan, Zabrina L. Brumme, Stephen J. O'Brien

Biology Faculty Articles

Background: As genome-wide sequence analyses for complex human disease determinants are expanding, it is increasingly necessary to develop strategies to promote discovery and validation of potential disease-gene associations.

Findings: Here we present a dynamic web-based platform – GWATCH – that automates and facilitates four steps in genetic epidemiological discovery: 1) Rapid gene association search and discovery analysis of large genome-wide datasets; 2) Expanded visual display of gene associations for genome-wide variants (SNPs, indels, CNVs), including Manhattan plots, 2D and 3D snapshots of any gene region, and a dynamic genome browser illustrating gene association chromosomal regions; 3) Real-time validation/replication …

Health Focused Education And Counseling For A Patient Diagnosed As Hiv Positive, Thomas W. Miller, Kate E. Bousaada, Lisa-Rose Rodriguez, Timothy Maggio, Jeanne Chadwick

Internet Journal of Allied Health Sciences and Practice

AIDS is a chronic, life-threatening condition caused by the human immunodeficiency virus (HIV). Examined is a patient education and counseling model applied to a patient with AIDS. Offered is a model utilizing problem based questions, goals and objectives and applied theory that is summarized in an algorithm of care for the patient with AIDS. Stages of HIV infection are used to facilitate clinical evaluation and plan therapeutic interventions. The process of health-focused counseling involves a number of critical components: assessment, patient education, health focused counseling, treatment intervention, and follow-up. The use of the health focused education and counseling model has …

Phenotypic Expressions Of Ccr5-Δ32/Δ32 Homozygosity, Giang T. Nguyen, Mary Carrington, Judith A. Beeler, Michael Dean, Louis M. Aledort, Philip M. Blatt, Alan R. Cohen, Donna Dimichele, M. Elaine Eyster, Craig M. Kessler, Barbara Konkle, Cindy Leissinger, Naomi Luban, Stephen J. O'Brien, James J. Goedert, Thomas R. O'Brien

Biology Faculty Articles

Objective: As blockade of CC-chemokine receptor 5 (CCR5) has been proposed as therapy for HIV-1, we examined whether the CCR5-Δ32/Δ32 homozygous genotype has phenotypic expressions other than those related to HIV-1.

Design: Study subjects were white homosexual men or men with hemophilia who were not infected with HIV-1. In this study, 15 CCR5-Δ32/Δ32 homozygotes were compared with 201 CCR5 wild-type (+/+) subjects for a wide range of clinical conditions and laboratory assay results ascertained during prospective cohort studies and routine clinical care. CCR5-Δ32 genotype was determined by polymerase chain reaction, followed by single-stranded conformational polymorphism analysis.

Results: …