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2020

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Full-Text Articles in Medicine and Health Sciences

The Effects Of The Rewalk^(Tm) Robotic System On Walking Capability In Paraplegic Spinal Cord Injury Patients In Taiwan, Alice Cw Tang, Shao An Lee, Albert Ck Chen, Ching Yu Wang, Wan Yu Chou, Show Chun Chen, Chih Lin Wu, Simon Fuk Tan Tang Dec 2020

The Effects Of The Rewalk^(Tm) Robotic System On Walking Capability In Paraplegic Spinal Cord Injury Patients In Taiwan, Alice Cw Tang, Shao An Lee, Albert Ck Chen, Ching Yu Wang, Wan Yu Chou, Show Chun Chen, Chih Lin Wu, Simon Fuk Tan Tang

Rehabilitation Practice and Science

Background: The ReWalk^(TM) system is an exoskeleton robotic device developed for ambulation assistance in patients with paraplegic spinal cord injury (SCI). The purpose of this study is to evaluate the safety and walking capability of the ReWalk^(TM) system for patients with paraplegic spinal cord injury in Taiwan. Methods: Eight patients with SCI and paraplegia were recruited for the study in a period from April 2015 to April 2016. The level of injuries ranged from T4 to T11. Assessments included the continuous walking time, the continuous walking distance, 6-minute walking test and 10-meter walking test after training for forty hours. Results: …


Evaluation Of Clinical Morbidities And Their Influence On Quality Of Life In Patients With Oral Cavity Cancer After Radiotherapy, Hao-Wei Tang, Tung-Hao Chang, Kuan-Lin Chen, Kuo-Yang Tsai, Su-Fen Liao, Wei-Te Wang Dec 2020

Evaluation Of Clinical Morbidities And Their Influence On Quality Of Life In Patients With Oral Cavity Cancer After Radiotherapy, Hao-Wei Tang, Tung-Hao Chang, Kuan-Lin Chen, Kuo-Yang Tsai, Su-Fen Liao, Wei-Te Wang

Rehabilitation Practice and Science

Background: Oral cavity cancer is the most common cancer in middle-aged men in Taiwan. Radiation fibrosis syndrome and lymphedema are the leading side effects in patients with oral cavity cancer, and can deteriorate their quality of life (QOL). The aim of this study was to prospectively evaluate common morbidities and their influences on QOL in patients with oral cavity cancer. Methods: 27 patients with oral cavity cancer who received surgery and radiotherapy (RT) were recruited. Clinical evaluations of each patient included the VAS pain scale, the lymphedema scale, facial distance measurement for lymphedema, maximal interincisal distance (MID), range of motion …


Prevalence Of Nail Changes In Patients Infected With Hiv - A Cross Sectional Study, Seethalakshmi Ganga Vellaisamy, Priya Jeyaraman, Kannan Gopalan Dec 2020

Prevalence Of Nail Changes In Patients Infected With Hiv - A Cross Sectional Study, Seethalakshmi Ganga Vellaisamy, Priya Jeyaraman, Kannan Gopalan

Journal of General - Procedural Dermatology & Venereology Indonesia

Introduction: The spectrum of nail changes is wider and their frequency is higher among HIV patients. These changes magnify the range and multiplicity of AIDS manifestations. Their systematic examination is a non-invasive method of possible diagnostic value.

Objective: The present study was conducted to study the frequency and types of nail changes in HIV infected individuals and to correlate the severity of nail changes with CD4 count.

Material and Method: This was a cross sectional study, conducted in Skin & STD Out-Patient department in a tertiary care hospital between March 2018 and April 2019. A total of …


2020-12-30_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services Dec 2020

2020-12-30_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …


Comparison Of Medicaments Used In Regenerative Endodontics In Terms Of Dentin Microhardness And Adhesion Of Mineral Trioxide Aggregate, Esma Saricam, Neslihan Bulak, Esra Özyurt, Suat Özcan Dec 2020

Comparison Of Medicaments Used In Regenerative Endodontics In Terms Of Dentin Microhardness And Adhesion Of Mineral Trioxide Aggregate, Esma Saricam, Neslihan Bulak, Esra Özyurt, Suat Özcan

Journal of Dentistry Indonesia

Eliminating microorganisms in the root canal system is important for the success of regenerative endodontics. Objective: This study evaluated the effects of different antibiotic pastes used for regenerative endodontic procedures on dentin microhardness and the push-out bond strength of mineral trioxide aggregate (MTA) to root canal dentin. Methods: Sixty-four maxillary central incisors were instrumented and randomly divided into the following four groups (n = 16) for medicament treatment: triple antibiotic paste, amoxicillin+clavulanic acid, cefaclor, and control (no dressing). After 21 days, two root segments were obtained by sectioning the roots horizontally for push-out and microhardness evaluations. MTA was placed into …


Effect Of Craniofacial Growth Pattern On Head Posture, Burak Kale, Muhammed Hilmi Buyukcavus Dec 2020

Effect Of Craniofacial Growth Pattern On Head Posture, Burak Kale, Muhammed Hilmi Buyukcavus

Journal of Dentistry Indonesia

Head posture refers to the upright position of the head of a standing or sitting subject. The literature reports that head posture is affected by many factors. Objective: To evaluate differences in head posture according to craniofacial growth pattern. Methods: A total of 163 individuals (83 females and 80 males) were included in this study. Patients were divided into three groups according to ANB angle as Class I, Class II, and Class III, and each group was divided further into three subgroups according to SN/GoGn angle as hyperdivergent, normodivergent, and hypodivergent. The patients were compared in terms of head posture …


Evaluation Of Maxillary Impacted Teeth And Their Relationship With Adjacent Teeth And Anatomic Structures With Cone Beam Computed Tomography, Emre Köse, Emin Murat Canger Dec 2020

Evaluation Of Maxillary Impacted Teeth And Their Relationship With Adjacent Teeth And Anatomic Structures With Cone Beam Computed Tomography, Emre Köse, Emin Murat Canger

Journal of Dentistry Indonesia

Objective: This study aimed to examine the cone beam computed tomography (CBCT) images of impacted maxillary canines and mesiodentes. Methods: This retrospective radiographic study was performed on 177 patients with 200 impacted maxillary canines and 12 mesiodentes. Using CBCT images, the unilateral/bilateral occurrence, presence of root dilaceration, mesio-distal and buccopalatal location, impaction condition, contact region of adjacent teeth, presence and degree of root resorption of adjacent teeth, dental follicle width, closest distance to the nasal cavity, nasopalatinal canal, and maxillary sinus were assessed. For mesiodentes, the types, follicle width, direction, and relationship with anatomical structures were evaluated. Results: No statistical …


Reliability Of Panoramic Radiography For Vertical Facial Pattern Assessment, Waqar Jeelani, Maheen Ahmed, Shakeel Ahmed Dec 2020

Reliability Of Panoramic Radiography For Vertical Facial Pattern Assessment, Waqar Jeelani, Maheen Ahmed, Shakeel Ahmed

Journal of Dentistry Indonesia

The orthopantomogram (OPG) is a common dental screening radiograph that has multiple implications. However, lateral cephalogram is the investigation of choice for the assessment of vertical facial pattern. Objective: The aim of the current study was to investigate the validity of an OPG parameter i.e. panoramic gonial angle (PGoA) for the assessment of the vertical facial pattern. Methods: A cross-sectional study was conducted on the pretreatment OPG and lateral cephalograms of 200 orthodontic patients aged 15-40 years. The PGoA was measured on both sides and an average was used for statistical analysis. The Pearson’s correlations of PGoA were measured with …


Conservative Management Of A Maxillary Lateral Incisor With An Apical Third Root Perforation: A Case Report, Nurul Astrina Damayanti, Dian Natalina Fuddjiantari, Tri Endra Untara, Yulita Kristanti Dec 2020

Conservative Management Of A Maxillary Lateral Incisor With An Apical Third Root Perforation: A Case Report, Nurul Astrina Damayanti, Dian Natalina Fuddjiantari, Tri Endra Untara, Yulita Kristanti

Journal of Dentistry Indonesia

Perforation is one of iatrogenic factors responsible for endodontic failure. Root canal perforation can occur at the cervical, mid-root, or apical levels. Non-surgical (conservative) perforation repair offers less tissue destruction and easy isolation during treatment. Objective: To explain the management of apical third root perforation using the conservative technique. Case Report: This case report describes a 29-year-old patient who came for management of right maxillary lateral incisor with apical third root perforation on the labial aspect. The location of apical third root perforation was evaluated using cone beam computed tomography (CBCT). Root perforation was sealed using mineral trioxide aggregate (MTA). …


Comparative Evaluation Of Apical Extrusion Debris And Irrigant During Calcium Hydroxide Removal And Endodontic Instrumentation Using Three Types Of Instrumentation Systems, Selen İnce Yusufoğlu, Esma Saricam Dec 2020

Comparative Evaluation Of Apical Extrusion Debris And Irrigant During Calcium Hydroxide Removal And Endodontic Instrumentation Using Three Types Of Instrumentation Systems, Selen İnce Yusufoğlu, Esma Saricam

Journal of Dentistry Indonesia

Many root canal preparation techniques and instruments produce apically extruded materials to a certain extent depending on the preparation system adopted. The extrusion of debris from the apical foramen during chemomechanical preparation may cause postoperative pain and failure of endodontic treatment. Objective: This study evaluates the differences in the apical extrusion of debris and calcium hydroxide (CH) during endodontic instrumentation by using Reciproc Blue (RB), WaveOne Gold (WOG), and F6 Skytaper (F6). Methods: Six experimental study groups (n = 13) were established. The root canal procedures for all groups were prepared with different methods: Group I: One Shape (OS) instrumentation, …


Trimming And Ph Effects On Nickel Ion Release From Stainless Steel Crowns Of Primary Teeth, Milad Arab-Nozari, Mohammad Shokrzadeh, Nastaran Zamehran, Jamshid Yazdani Charati, Azam Nahvi Dec 2020

Trimming And Ph Effects On Nickel Ion Release From Stainless Steel Crowns Of Primary Teeth, Milad Arab-Nozari, Mohammad Shokrzadeh, Nastaran Zamehran, Jamshid Yazdani Charati, Azam Nahvi

Journal of Dentistry Indonesia

Objective: Stainless steel crowns (SSCs) are preformed metal crowns used to restore severely decayed primary teeth. The aim of this study is to evaluate the effects of pH changes and SSC margin trimming on nickel release in artificial saliva solution. Methods: A total of 90 SSCs were divided into three groups and placed in 35 ml of artificial saliva of pH 6.8, 5, and 3.5. Another group consisting 30 SSCs with trimmed margins was placed in saliva of pH 6.8. All SSCs were incubated at 37°C. The concentration of released nickel was assessed on days 1, 7, 14, 21, and …


Complete Edentulism Of Dental Patients In Northeastern Turkey: Prevalence And Radiographic Findings On Panoramic Radiographs, Elif Sadik, Ceren Gökmenoğlu, Cankat Kara Dec 2020

Complete Edentulism Of Dental Patients In Northeastern Turkey: Prevalence And Radiographic Findings On Panoramic Radiographs, Elif Sadik, Ceren Gökmenoğlu, Cankat Kara

Journal of Dentistry Indonesia

The prevalence of complete edentulism varies from country to country and from one region to another. Previous studies have reported the high prevalence of significant radiographic findings in edentulous patients. Objectives: This study aimed to determine the prevalence of complete edentulism retrospectively and to evaluate the frequency and location of significant radiographic findings on panoramic radiographs in edentulous jaws of dental patients in northeastern Turkey. Methods: The digital panoramic images of all ≥35 year-old patients admitted to our faculty from January 2014 to August 2015 were evaluated. The prevalence of complete edentulism was determined among 8314 panoramic images retrospectively. Radiographic …


Comparison Of Popular Three-Dimensional Printing Materials For Oral And Maxillofacial Surgical Guidance Model, Mohammad Adhitya, Sunarso Sunarso, Abdul Muis Dec 2020

Comparison Of Popular Three-Dimensional Printing Materials For Oral And Maxillofacial Surgical Guidance Model, Mohammad Adhitya, Sunarso Sunarso, Abdul Muis

Journal of Dentistry Indonesia

The application of three-dimensional (3D) models in the medical field has become popular. However, the accuracy of 3D models for surgical guidance varies among different materials and 3D printing technologies, such as printing machine usage. Objectives: This study aims to obtain more information about the effect of three different materials printed using a fused deposition material printer from the same digital data source. This study also aims to compare, analyze, and test the materials’ ability. Methods: Each of the filament materials (acetylbutane stearate [ABS], polylactic acid [PLA], and high-impact polystyrene [HIPS]) are printed at two infill densities, their weight, volume, …


Effect Of Salivary Ph On Water Absorption And Solubility Of Enhanced Resin- Modified Glass Ionomer, Yosi Kusuma Eriwati, Muhammad Dhiaulfikri, Ellyza Herda Dec 2020

Effect Of Salivary Ph On Water Absorption And Solubility Of Enhanced Resin- Modified Glass Ionomer, Yosi Kusuma Eriwati, Muhammad Dhiaulfikri, Ellyza Herda

Journal of Dentistry Indonesia

The influence of immersion period and liquid pH on water absorption capacity and solubility of the resin-modified glass ionomer cement (RMGIC) raises the question of whether the critical pH of hydroxyapatite and fluoroapatite influences the water absorption capacity and solubility of enhanced resin-modified glass ionomer (ERMGI). Objective: This study was designed to investigate the effects of immersion periods and various pH levels of artificial saliva on the water absorption and solubility of RMGIC and ERMGI. Methods: Fifty-four disc-shaped specimens (15 mm x 1 mm) of enhanced RMGI (ACTIVATM BioACTIVE-RESTORATIVE, Pulpdent, Watertown, MA, USA) and 54 disc-shaped specimens (15 mm x …


An Assessment Of Knowledge, Attitude, And Practice Of The Kuantan Community On The Effects Of Monosaccharides On Cancer, Muhammad Alif Mazlan, Muhammad Kamil Che Hasan, Afzan Mat Yusof, Muhammad Lokman Md Isa Dec 2020

An Assessment Of Knowledge, Attitude, And Practice Of The Kuantan Community On The Effects Of Monosaccharides On Cancer, Muhammad Alif Mazlan, Muhammad Kamil Che Hasan, Afzan Mat Yusof, Muhammad Lokman Md Isa

Makara Journal of Health Research

Background: Cancer knowledge, attitude, and practice (KAP) levels of communities are essential to be assessed to enhance cancer educational programs. This study aimed to determine the KAP level of the Kuantan community on the effects of monosaccharides on cancer. The association between the sociodemographic data and KAP level of the community has also been evaluated.

Methods: A cross-sectional survey was performed among residents living in the Kuantan community. Only 303 of 380 responses were included in the data analysis using the chi-square test.

Results: The knowledge and practice levels were moderate, whereas the attitude was at a …


Dental Caries Among 12-Year-Old Children After Discontinuation Of Water Fluoridation In Pahang, Malaysia, Faizah Abdul Karim, Zamros Yuzadi Mohd Yusof, Nor Azlida Mohd Nor Dec 2020

Dental Caries Among 12-Year-Old Children After Discontinuation Of Water Fluoridation In Pahang, Malaysia, Faizah Abdul Karim, Zamros Yuzadi Mohd Yusof, Nor Azlida Mohd Nor

Makara Journal of Health Research

Background: Water fluoridation (WF) has been a national caries prevention program in Malaysia since 1972. However, between July 2012 and December 2013, WF was discontinued in Pahang. This study aimed to compare caries prevalence and mean caries experience among Malaysian children in WF and WF-ceased areas and determine its associated risk factors.

Methods: This cross-sectional study was conducted among 12-year-old schoolchildren in two Malaysian states: Pahang (WF-ceased) and Perak (WF-continued). Dental caries was examined using ICDAS criteria, and a questionnaire was used to collect relevant data. Associations between independent variables and dental caries were analyzed by simple logistic …


Psychosocial Impacts Of Fixed Orthodontic Treatment In Lahore, Pakistan, Hazik Bin Shahzad, Dalia Iftikhar, Noor Ul Huda, Nayha Enver, Faiza Awais, Shabbir Hussain Dec 2020

Psychosocial Impacts Of Fixed Orthodontic Treatment In Lahore, Pakistan, Hazik Bin Shahzad, Dalia Iftikhar, Noor Ul Huda, Nayha Enver, Faiza Awais, Shabbir Hussain

Makara Journal of Health Research

Background: The aim of this study is to assess psychosocial impacts on oral health-related quality of life between individuals currently undergoing orthodontic treatment and those who have completed treatment.

Methods: A total of 135 individuals were selected from the Orthodontic Department at Rashid Latif Dental Hospital, Lahore, Pakistan. Current and previous orthodontic treatments were recorded. A questionnaire on oral impacts on daily performance was used to assess functional, psychological, and social limitations.

Results: The most prevalent psychosocial impact was difficulty in smiling/laughing (26.6%). Logistic regression analysis showed that individuals currently undergoing orthodontic treatment are 2.9 times more …


Self-Assessment Tool For Evaluating Periodontal Conditions, Haslina Rani, Tuti Ningseh Mohd-Dom, Shahida Mohd-Said, Nur Azwani Johari Dec 2020

Self-Assessment Tool For Evaluating Periodontal Conditions, Haslina Rani, Tuti Ningseh Mohd-Dom, Shahida Mohd-Said, Nur Azwani Johari

Makara Journal of Health Research

Background: The global prevalence of periodontal disease is steadily rising. Early detection through the active screening of potential patients is important because periodontal disease leads to high disease, clinical, and economic burdens. The aim of this study is to develop a simple periodontal assessment tool for the Malay-speaking population; this tool is referred to in this work as MyGusi.

Methods: Translation and back-translation of a self-assessment tool containing 10 items related to periodontal health conditions and risk behaviors were conducted by three bilingual translators. Nine periodontists were selected to determine the content validity of the tool. After pre-testing …


Right To Health In Gats: Can The Public Health Exception Pave The Way For Complementarity?, Swati Gola Dec 2020

Right To Health In Gats: Can The Public Health Exception Pave The Way For Complementarity?, Swati Gola

Pace International Law Review

This paper demonstrates how a right to health approach in the interpretation of the public health exception outlined in GATS Article XIV(b) can bring about a harmonious application of international human rights and international trade law regimes. Focusing on the interpretive value of the right to health for the public health exception in GATS, it examines whether a WTO Member, who has committed itself under GATS to fully liberalize all service sectors that have implications for health (e.g., hospital and other healthcare services), still retains the regulatory space to undertake measures to fulfill their right to health obligations and can …


The Possible Protective Role Of Vitamin E On The Induced Silver Nanoparticles Toxicity On Filiform And Circumvallate Tongue Papillae Of Albino Rats Histological And Immunohistochemical Study, Nada Tarek Zaki, Mahmoud Al Ankily, Reham Magdy Amin, Ahmed Mahmoud Halawa Dec 2020

The Possible Protective Role Of Vitamin E On The Induced Silver Nanoparticles Toxicity On Filiform And Circumvallate Tongue Papillae Of Albino Rats Histological And Immunohistochemical Study, Nada Tarek Zaki, Mahmoud Al Ankily, Reham Magdy Amin, Ahmed Mahmoud Halawa

Dentistry

Recently Silver nanoparticles (AgNPs) are widely used as in manufacturing of filters to purify drinking water, as a part of surgical prosthesis, splints, dental alloys and most importantly in the medical field as a bactericidal, fungicidal and as a therapeutic agent. Although these widely usage of AgNPs, can induce toxicity. to evaluate the protective role of vitamin Eon the induced silver nanoparticles toxicity on filiform and circumvallate tongue papillae of albino rats. twenty-eight male albino rats weighing 200-250 grams were divided into; the control and the experimental groups, which is subdivided into, subgroup I receiving AgNPs and subgroup II receiving …


Drug-Induced Sleep Endoscopy (Dise) With Simulation Bite To Predict The Success Of Oral Appliance Therapy In Treating Obstructive Sleep Apnea/Hypopnea Syndrome (Osahs), Pietro De Luca Dec 2020

Drug-Induced Sleep Endoscopy (Dise) With Simulation Bite To Predict The Success Of Oral Appliance Therapy In Treating Obstructive Sleep Apnea/Hypopnea Syndrome (Osahs), Pietro De Luca

Translational Medicine @ UniSa

Oral appliances have gained their place in the treatment of obstructive sleep apnea (OSA) where custom-made titratable mandibular advancement devices (MAD) have become the oral appliance of choice. This study aimed to asses the value of the drug-induced sleep endoscopy (DISE) using a MAD in the prediction of treatment outcome for OSAHS

This is a prospective, single-center cohort study that enrolled sixty-six consecutive patients with diagnosed OSA (5 events/h < apnea-hypopnea index (AHI) < 50 events/h) to be treated with a custom-made titratable MAD. The patients were evaluated polysomnographically with the MAD in situ after the adaptation and titration period of 3 months. The associations between findings during DISE and treatment outcome were assessed.

The subjects showed a wide range of severity of OSAHS pre-treatment: median AHI was 43.10 with a range from 20.13 to 66.07. The simulation bite was associated with a significant increase …


2020-12-23_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services Dec 2020

2020-12-23_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …


Stress Relaxation In Orthodontic Aligner Plastics; An In Vitro Comparison Study, Kristopher J. Keller Dec 2020

Stress Relaxation In Orthodontic Aligner Plastics; An In Vitro Comparison Study, Kristopher J. Keller

Theses & Dissertations

The purpose of this study was to ascertain if repeated stresses from extension cycling would result in accumulated damage in aligner materials and affect force delivery. A secondary goal was to identify potential differences in mechanical behavior present among orthodontic aligner polymers. Four thermoplastic polymers (Essix ACE, Taglus, Zendura, and Zendura FLX) were thermoformed, cut into strips, and extension cycled to 0.4 millimeters in a 37C water bath. Force decay, maximum and minimum force, and elastic modulus were measured during cycling. Additional samples were subjected to controlled tension until failure, allowing the measurement of yield strength, ultimate strength, and elastic …


Inflammatory Cytokine Expression Of Immune Cells On Exposure To Invisalign® Material: An In Vitro Pilot Study, Alaina M. Allen Dec 2020

Inflammatory Cytokine Expression Of Immune Cells On Exposure To Invisalign® Material: An In Vitro Pilot Study, Alaina M. Allen

Theses & Dissertations

The purpose of this study is to characterize the inflammatory cytokines that are expressed in peripheral blood mononuclear cells (PBMCs) and THP-1 monocytes exposed to Invisalign® aligner material in vitro. Invisalign® material was ground into particles, soaked in artificial saliva, and the eluate was collected. Commercially available cryopreserved pooled and individual human PBMCs and THP-1 monocytes were cultured with Invisalign® material eluate and positive (lipopolysaccharide) and negative controls. The supernatants were collected and used with a BioLegend LEGENDplexmulti-analyte flow assay, a sandwich enzyme-linked immunosorbent assay (ELISA), to identify the expression of TNF-α, IL-6, IL-8, IL-10, …


Long-Acting Nanoformulated Antivirals For The Treatment And Prevention Of Hiv-1 And Hbv Infections, Dhruvkumar M. Soni Dr. Dec 2020

Long-Acting Nanoformulated Antivirals For The Treatment And Prevention Of Hiv-1 And Hbv Infections, Dhruvkumar M. Soni Dr.

Theses & Dissertations

While antiretroviral therapy (ART) has revolutionized treatment and prevention of human immunodeficiency virus type one (HIV-1) infection, regimen adherence, viral mutations, drug toxicities, stigma and pill fatigue are limitations. These have led to the development of long acting (LA) ART. These include, but are not limited to, implantable devices, new chemical entities, prodrug modifications and nanoformulations. To these ends, this thesis focues on the transformation of nucleoside reverse transcriptase inhibitors (NRTIs) into LA parenterals, While elusive, data from our laboratories demonstrated that modifications to the PROdrug and nucleoTide technology (ProTide) enables improvements in drug apparent half-life and tissue and cell …


Outcomes Of Unilateral Alveolar Clefts Grafted Using Recombinant Human Bone Morphogenetic Protein-2: A Retrospective Volumetric Analysis Using Cbct, Landon Robert Peterson Dec 2020

Outcomes Of Unilateral Alveolar Clefts Grafted Using Recombinant Human Bone Morphogenetic Protein-2: A Retrospective Volumetric Analysis Using Cbct, Landon Robert Peterson

Theses & Dissertations

Purpose of this study is to evaluate the success rates of secondary alveolar grafts using recombinant human bone morphogenetic protein with CBCT and to evaluate the effects of several variables on these outcomes. After our inclusion/exclusion criteria, records of 24 patients receiving secondary alveolar grafts at the University of Nebraska Medical Center were evaluated. Pre-graft and 6-month post-graft cleft volumes were measured using ITK-SNAP 3.8.0 software to determine a percent residual defect following surgery. Of the 24 patients, one was excluded as the graft surgery was deemed a failure. The patients’ gender, age, side of cleft, cleft side canine root …


2020-12-17_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services Dec 2020

2020-12-17_Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_102057---,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …


Interprofessional Education (Ipe) And Interprofessional Education Collaborative (Ipec) Competencies Of Clinical And Healthcare Administration Undergraduate Students, Shelly Gompf Dec 2020

Interprofessional Education (Ipe) And Interprofessional Education Collaborative (Ipec) Competencies Of Clinical And Healthcare Administration Undergraduate Students, Shelly Gompf

Dissertations, Theses, and Projects

The healthcare industry is dependent on the successful delivery of effective education to undergraduate healthcare students. Curriculum and instruction, experiences both inside and outside of the classroom, significantly contribute to students' successful development. A critical element for successful healthcare delivery is to continue building a sustainable culture for all healthcare workers that will increase skills for improved ethics and values, inter-disciplinary understanding of roles and responsibilities, interprofessional communication, and teamwork. One teaching approach that continues to produce positive results is interprofessional education (IPE). This teaching method, supported by the experiential learning theory, brings clinical stakeholders together to problem-solve and make …


The Brief Case:, Eileen M Burd, Ahmed Babiker, Jessica K Fairley, Divya Bhamidipati, Laila E Woc-Colburn, Blaine A Mathison Dec 2020

The Brief Case:, Eileen M Burd, Ahmed Babiker, Jessica K Fairley, Divya Bhamidipati, Laila E Woc-Colburn, Blaine A Mathison

Journal Articles

No abstract provided.


Mapping Routine Measles Vaccination In Low- And Middle-Income Countries, Alyssa N. Sbarra, Simon I. Hay, Stephen S. Lim, Jonathan F. Mosser, Veincent Christian F. Pepito, Local Burden Of Disease Vaccine Coverage Collaborators, 634 Co-Authors Dec 2020

Mapping Routine Measles Vaccination In Low- And Middle-Income Countries, Alyssa N. Sbarra, Simon I. Hay, Stephen S. Lim, Jonathan F. Mosser, Veincent Christian F. Pepito, Local Burden Of Disease Vaccine Coverage Collaborators, 634 Co-Authors

Ateneo School of Medicine and Public Health Publications

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs). Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19). Here we generated annual estimates of routine childhood MCV1 …