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Full-Text Articles in Medicine and Health Sciences
The Potential Of Salvia Officinalis As A Suppressor Of Cell Proliferation In Animal Feed And Human Nutrition: An Experimental Stud, Muhammet Kuddusi̇ Erhan
The Potential Of Salvia Officinalis As A Suppressor Of Cell Proliferation In Animal Feed And Human Nutrition: An Experimental Stud, Muhammet Kuddusi̇ Erhan
Turkish Journal of Veterinary & Animal Sciences
The objective of this study was to examine the in vitro cytotoxic activities of Salvia officinalis (sage) oil on human immortalized keratinocyte (HaCaT) cell lines by using an [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide] (MTT) cytotoxicity assay after the Salvia officinalis oil administration in different doses and time-points. In vitro cytotoxic activities of Salvia officinalis oil on HaCaT cell lines were assessed, and MTT assays were used to determine cell viability. The HaCaT cells (100 µL) were cultured in 96well plates at 2 × 104 cells per well and treated with different concentrations of Salvia officinalis oil (25 µM, 50 µM, 100 µM, 150 µM, …
The Anti Proliferative Effects Of Rosemary Oil On Keratinocyte Cell Line, Hacat, Muhammet Kuddusi̇ Erhan
The Anti Proliferative Effects Of Rosemary Oil On Keratinocyte Cell Line, Hacat, Muhammet Kuddusi̇ Erhan
Turkish Journal of Veterinary & Animal Sciences
This study aims to investigate the action of rosemary oil on the immortalized keratinocyte cell line. Samples of Rosmarinus officinalis that were growing uncultivated in central Turkey were harvested during flowering in May 2016. The rosemary oil was obtained by the hydrodistillation of the dried ground material in a Clevenger-like apparatus. Human cells from the immortalized nontumorigenic keratinocyte cell line were seeded at a concentration of 5000 cells/well on 96 well plates. Cell viability was measured at the 24, 48, and 72 h. Five different doses of 1.25% to 20% Rosmarinus officinalis oil, 20% DMSO (for toxic examination), and 1 …
Evaluation Of Cytotoxic, Apoptotic Effects And Phenolic Compounds Of Sea Cucumberholothuria Tubulosa (Gmelin, 1791) Extracts, Mehli̇ka Alper, Melek Güneş
Evaluation Of Cytotoxic, Apoptotic Effects And Phenolic Compounds Of Sea Cucumberholothuria Tubulosa (Gmelin, 1791) Extracts, Mehli̇ka Alper, Melek Güneş
Turkish Journal of Veterinary & Animal Sciences
This study aimed to investigate the potential cytotoxic effects and phenolic contents of aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Muğla (Turkey) against different cancer cells for the first time. An MTT assay was carried out to determine cellular viability. Apoptotic cell death was determined using flow cytometry. DNA fragmentation assay and caspase-3 activity analysis were carried out. Both extracts were analyzed by high performance liquid chromatography (HPLC) for quantification of phenolic compounds. Both HTS and HTM extracts generally caused a decrease in the cell viability in a concentration- and timedependent manner. The lowest IC$_{50}$ value …