Medicine and Health Sciences Commons^™

Aci-35 And Aadvac1 Active Immunotherapy As Preventative Treatment Options For Chronic Traumatic Encephalopathy, Emily C. Boehlein

Selected Honors Theses

One of the most common, as well as one of the most dangerous injuries amongst athletes today is mild traumatic brain injury (mTBI), commonly known as concussion. Aside from physical symptoms such as nausea, dizziness, and headaches; concussions have can have longterm effects on brain physiology. A common neurological disease that can result from multiple concussions is Chronic Traumatic Encephalopathy (CTE), characterized by symptoms such as severe depression, anxiety, confusion, and aggression; amongst others.1 On the cellular level, CTE is classified by a unique pathway that leads to the hyperphosphorylation of tau protein and subsequent clumping of tau-containing neurofibrillary tangles …

Rodeo Athletes' Perceptions On Head Injuries: Focusing On Concussions, Alyssa Mckenzie, Jennifer Walker, Erika Smith-Goodwin

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Please enjoy Volume 6, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports.

Thank you for viewing this 6^th Annual OATA Special Edition.

Validation Of An Instrument To Assess Return To Play And Return To Learn Protocols In Adolescents Diagnosed With A Sport Related Concussion, Hogan Marshall, Janet E. Simon, Laura L. Harris

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Please enjoy Volume 6, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports.

Thank you for viewing this 6^th Annual OATA Special Edition.

Validation Of An Instrument To Assess Fear Avoidance In Adolescents Who Have Been Diagnosed With A Concussion, Erika Smith, Janet Simon, Laura Harris

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Please enjoy Volume 6, Issue 1 of the JSMAHS. In this issue, you will find Professional, Graduate, and Undergraduate research abstracts, and case reports.

Thank you for viewing this 6^th Annual OATA Special Edition.

Cumulative Purposeful Soccer Heading Can Lead To Compensatory Changes In Brain Activity During Combined Moderate Exercise And Cognitive Load In Female Youth Soccer Players, Alexandra Harriss

Electronic Thesis and Dissertation Repository

Head trauma that occurs during sporting events is responsible for an increasing number of emergency department visits in Canada and is associated with an increased risk of developing neurodegenerative diseases.While head injury in American football has been extensively studied, it cannot be extrapolated to non-helmeted sports. Approximately 265 million people are actively participating in soccer and many are 18 years of age and younger. Soccer is unique in that players use their head to redirect the ball; however, the effects of cumulative purposeful soccer heading on brain health are unknown. Accordingly, the objective of this thesis was to quantify head …

Understanding And Identifying The Knowledge And Attitudes Of High School Coaches On Sport-Related Concussions, Marc A. Mortellaro

Seton Hall University Dissertations and Theses (ETDs)

Background and Purpose of the Study: Sport-related concussions are a major public health issue, particularly so in the setting of sports. Sports dominate American culture and with millions of athletes of all ages participating in these sports these athletes predispose themselves to the risks of sport-related concussions. High-school athletes are of particular interest because of the heightened risks of long-term consequences and of particular note second impact syndrome, which is a catastrophic injury primarily reported in the adolescent aged athlete. Appropriate concussion assessment and management is necessary for reducing the possibility of these long- term effects of concussions. Properly trained …

King-Devick Test Score Is Linked To Cerebral Vasoreactivity During Acute Recovery Phase Post-Concussion, Madison E. Mccredie, Abigail Reichow, Mathew Stokes, Kathleen R. Bell, Sushmita Purkayastha

International Journal of Exercise Science: Conference Proceedings

The King-Devick (KD) test is a quick screening tool used to detect oculomotor and attention related brain function impairments following a concussion. Adequate cerebral blood flow (CBF) is an indicator of structural and functional integrity and impairments in CBF have been linked to cognitive deficits following concussion. Cerebral vasoreactivity (CVR), a key measure of hemodynamic reserve, is an important factor in CBFregulation. PURPOSE: To examine the association between CVR and oculomotor and attention function, using KD test scores, in collegiate athletes following a concussion. METHOD: Eighteen male and female athletes diagnosed with a sports-related concussion were enrolled in the prospective …

Impairments In Cerebral Autoregulation Is Associated With Postural Control In Sports Related Concussion, Abigail L. Reichow, Madison Mccredie, Mathew Stokes, Kathleen R. Bell, Sushmita Purkayastha

International Journal of Exercise Science: Conference Proceedings

Global and regional deficits in cerebral blood flow are reported with concussions, a major public health concern, with approximately 3.8 million incidences occurring annually in the United States alone. Recent studies have identified an increased risk of musculoskeletal injuries in athletes upon return-to-play. Complexity index is a sensitive marker of postural control, with low complexity index indicating a poor physiological adaptation to stress. PURPOSE: Twofold; 1. Examine complexity index and dynamic cerebral autoregulation (dCA) at rest and during physical stress (rhythmic squatting) in collegiate athletes following a concussion in comparison to non-injured controls. 2. Examine the association between complexity …

Exploring The Association Between Recent Concussion, Subconcussive Impacts And Depressive Symptoms In Male Australian Football Players, Sarah Ann Harris, Paola T. Chivers, Fleur L. Mcintyre, Ben Piggott, Max Bulsara, Fiona H. Farringdon

Research outputs 2014 to 2021

Objectives: To explore the association between depressive symptoms and recent head-related trauma (diagnosed concussion, subconcussive impacts) in semiprofessional male Australian Football (AF) players.

Methods: Sixty-nine semiprofessional male players from a West Australian Football League (WAFL) club participated in the study (M age =21.81, SD=2.91 years). Depressive symptoms were measured using the Centre for Epidemiological Studies Depression Scale. Injuries and potential confounding variables (eg, pre-existing mental health condition; alcohol or drug hangovers; experiencing a stressful event) were self-reported anonymously using the WAFL Injury Report Survey. Both tools were administered every 2-weeks over the first 22-weeks of the WAFL season. Controlling for …

Diagnosing Mild Traumatic Brain Injury Using Saliva Rna Compared To Cognitive And Balance Testing, Steven D. Hicks, Cayce Onks, Raymond Y. Kim, Kevin J. Zhen, Jayson Loeffert, Andrea C. Loeffert, Robert P. Olympia, Gregory Fedochak, Samantha Devita, Aakanksha Rangnekar, John Leddy, Mohammad N. Haider, Zofia Gagnon, Callan D. Mcloughlin, Matthew Badia, Jason Randall, Miguel Madeira, Aaron M. Yengo-Kahn, Justin Wenzel, Matthew Heller, Hallie Zwibel, Aaron Roberts, Samantha Johnson, Chuck Monteith, Michael N. Dretsch, Thomas R. Campbell, Rebekah Mannix, Christopher Neville, Frank Middleton

Rehabilitation Sciences Faculty Publications

BACKGROUND: Early, accurate diagnosis of mild traumatic brain injury (mTBI) can improve clinical outcomes for patients, but mTBI remains difficult to diagnose because of reliance on subjective symptom reports. An objective biomarker could increase diagnostic accuracy and improve clinical outcomes. The aim of this study was to assess the ability of salivary noncoding RNA (ncRNA) to serve as a diagnostic adjunct to current clinical tools. We hypothesized that saliva ncRNA levels would demonstrate comparable accuracy for identifying mTBI as measures of symptom burden, neurocognition, and balance.

METHODS: This case‐control study involved 538 individuals. Participants included 251 individuals with mTBI, enrolled …

Sleep And Stress In The Acute Phase Of Concussion In Youth, Arthur C. Maerlender, Caitlin Masterson, Jessica L. Calvi, Todd Caze, Ross Mathiasen, Dennis Molfese

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

This study sought to address the complex interplay between both biological and psychological perceptions of stress and sleep in the acute stages following a mild traumatic brain injury. A secondary goal was to identify potential targets for intervention. Eleven acutely injured youth (mean age 12 years) were studied at home with overnight actigraphy, salivary cortisol and melatonin assays, and subjective ratings of stress and fatigue (injured group). Nine matched control youth also were assessed (control group). Results suggested longer sleep latencies (time to fall asleep) and higher levels of fatigue in the injured group exist (p ¼ 0.025 and p …

Mild Traumatic Brain Injuries As A Possible Risk Factor For Anterior Cruciate Ligament Tears In Female High School And College Athletes, Brooke Weyand

Capstone Showcase

Introduction: Both mild traumatic brain injuries (concussions) and anterior cruciate ligament (ACL) tears are among two of the most common, and most career-ending sports medicine injuries. Concussions often result from a blow to the head that can cause headaches, difficulty concentrating, photophobia, and memory loss. Concussion recovery often involved brain rest from athletics, screen exposure, reading, lights, and if severe enough, academics. The ACL is a ligament that is detrimental in stabilization of the knee joint. It connects the femur to the tibia within the joint, and can tear suddenly if it undergoes a quick twisting motion. ACL tears often …

Assessing Classroom Readiness Post-Concussion In College Student-Athletes: Comparing The Impact To Standardized Cognitive Assessments, Isabel Hotop

All Theses, Dissertations, and Capstone Projects

The ImPACT (Immediate Post-Concussion Assessment and Cognitive Test) is a commonly used computerized neurocognitive test for concussion management in college student-athletes (Lovell, 2020). This assessment is heavily relied upon by athletic trainers to make decisions regarding timing of return-to-play and return-to-classroom for college student-athletes. Predicting when students are ready to return-to-learn is imperative for their success in the classroom. However, the current evidence shows that the validity and reliability of the ImPACT may be lacking. As of ten years ago, a single study had yet to demonstrate the validity of the ImPACT by comparing the scores to traditional neurocognitive testing …