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9th Annual Postdoctoral Science Symposium, University Of Texas Md Anderson Cancer Center Postdoctoral Association

Annual Postdoctoral Science Symposium Abstracts

The mission of the Annual Postdoctoral Science Symposium (APSS) is to provide a platform for talented postdoctoral fellows throughout the Texas Medical Center to present their work to a wider audience. The MD Anderson Postdoctoral Association convened its inaugural Annual Postdoctoral Science Symposium (APSS) on August 4, 2011.

The APSS provides a professional venue for postdoctoral scientists to develop, clarify, and refine their research as a result of formal reviews and critiques of faculty and other postdoctoral scientists. Additionally, attendees discuss current research on a broad range of subjects while promoting academic interactions and enrichment and developing new collaborations.

Predictive Diagnostic Analysis Of Mammographic Breast Tissue Microenvironment, Dexter G. Canning

Honors College

Improving computer-aided early detection techniques for breast cancer is paramount because current technology has high false positive rates. Existing methods have led to a substantial number of false diagnostics, which lead to stress, unnecessary biopsies, and an added financial burden to the health care system. In order to augment early detection methodology, one must understand the breast microenvironment. The CompuMAINE Lab has researched computational metrics on mammograms based on an image analysis technique called the Wavelet Transform Modulus Maxima (WTMM) method to identify the fractal and roughness signature from mammograms. The WTMM method was used to color code the mammograms …

Assessment Of Physical Fitness After Bariatric Surgery And Its Association With Protein Intake And Type Of Cholecalciferol Supplementation, Hendrika J M Smelt, Sjaak Pouwels, Alper Celik, Adarsh Gupta, Johannes F Smulders

Rowan-Virtua School of Osteopathic Medicine Faculty Scholarship

Background: Several studies showed that there is a relationship between vitamin and mineral status and muscle strength. In particular this is the case for handgrip strength (HS) and vitamin D deficiency. In bariatric surgery there is a risk of decrease in muscle strength after surgery and also vitamin and mineral deficiencies are not uncommon. The aim of this study is to assess the effect of low vitamin 25 (OH) cholecalciferol levels, high dose cholecalciferol supplementation regime and protein intake on physical fitness, measured using handgrip strength (HS) and the shuttle walk run test (SWRT). Methods: For this retrospective …

The Reproducibility Crisis In Scientific Research, Sarah Eline

Senior Honors Projects, 2010-2019

Following the push for evidence based practice, came a huge proliferation of research journals and journal articles. With this increase in quantity came an increased concern about the quality of these articles being published, which led to a multifield investigation regarding the reproducibility of scientific research. With studies in the fields of psychology and biomedicine only reaching approximately a 30% reproducibility rate, a conversation has been sparked that spans across every field of research. Upon further investigation, various causes for this reproducibility crisis have surfaced which include, lack of data sharing/ transparency, statistical errors, funding corruption, and the culture surrounding …

Do Patient Reported Outcome Measurement Information System (Promis) Scales Demonstrate Responsiveness As Well As Disease-Specific Scales In Patients Undergoing Knee Arthroscopy?, Raymond J. Kenney, Jeff Houck, Brian D. Giordano, Judith F. Baumhauer, Meghan Herbert, Michael D. Maloney

Faculty Publications - College of Physical Therapy

Background: The Patient Reported Outcomes Information System (PROMIS) is an efficient metric able to detect changes in global health. Purpose: To assess the responsiveness, convergent validity, and clinically important difference (CID) of PROMIS compared with disease-specific scales after knee arthroscopy. Study Design: Cohort study (Diagnosis); Level of evidence, 2.

Methods: A prospective institutional review board–approved study collected PROMIS Physical Function (PF), PROMIS Pain Interference (PI), International Knee Documentation Committee (IKDC), and Knee injury and Osteoarthritis Outcome Score (KOOS) results in patients undergoing knee arthroscopy. The change from preoperative to longest follow-up was used in analyses performed to determine responsiveness, convergent …

Current Research And Statistical Practices In Sport Science And A Need For Change, Jake R. Bernards, Kimitake Sato, G. Gregory Haff, Caleb D. Bazyler

Caleb D. Bazyler

Current research ideologies in sport science allow for the possibility of investigators producing statistically significant results to help fit the outcome into a predetermined theory. Additionally, under the current Neyman-Pearson statistical structure, some argue that null hypothesis significant testing (NHST) under the frequentist approach is flawed, regardless. For example, a p-value is unable to measure the probability that the studied hypothesis is true, unable to measure the size of an effect or the importance of a result, and unable to provide a good measure of evidence regarding a model or hypothesis. Many of these downfalls are key questions researchers strive …

Reporting Number Needed To Treat In Clinical Trials Published In Physical Therapy Specific Literature 1989 - 2018, Susan Ann Talley

Wayne State University Dissertations

Evidence-based practice requires physical therapists to make clinical decisions about the best intervention to use when providing services to patients/clients. Although null hypothesis significance testing (NHST) is frequently used to interpret the outcome of a clinical trial investigating the comparative effectiveness of an intervention, statistical significance does not directly translate into clinical importance. Number needed to treat (NNT) is a measure of effect size (ES) that may be particularly useful when translating the results from clinical trials to PT clinical practice. The purpose of this study was to conduct a bibliometric content analysis of the methods of reporting research results …

Artificial Intelligence: Practical Primer For Clinical Research In Cardiovascular Disease, Nobuyuki Kagiyama, Sirish Shrestha, Peter D. Farjo, Partho P. Sengupta

Faculty & Staff Scholarship

No abstract provided.

Strong Side, Weak Side: Goal Generating Tactics In Ncaa Men's Water Polo, Joey Gullikson

University of the Pacific Theses and Dissertations

In the game of water polo, it is generally accepted that the shooting position of the offensive player and the tactic employed are both important in generating goals. Despite their importance, little is known about the relationship between shooting position and offensive tactics and their impact on the probability of goal scoring. In this research, a sequence of hierarchical mixed logistic regression models is applied to a unique data set from 2016 and 2017 NCAA men’s water polo seasons to analyze the relationship between goal generating tactics and different shooting positions. The primary result reveals that the closer a player …

Response Shift After A 4-Week Multimodal Intervention For Chronic Ankle Instability, Cameron J. Powden, Matthew C. Hoch, Beth E. Jamali, Johanna M. Hoch

Rehabilitation Sciences Faculty Publications

Context The accurate evaluation of self-reported changes in function throughout the rehabilitation process is important for determining patient progression. Currently, how a response shift (RS) may affect the accuracy of self-reported functional assessment in a population with chronic ankle instability (CAI) is unknown.

Objective To examine the RS in individuals with CAI after a 4-week multimodal rehabilitation program.

Design Controlled laboratory study.

Setting Laboratory.

Patients or Other Participants Twenty adults (5 men, 15 women; age = 24.35 ± 6.95 years, height = 169.29 ± 10.10 cm, mass = 70.58 ± 12.90 kg) with self-reported CAI participated. Inclusion criteria were at …

Consultation Experience In Public Health, Zimu Li

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Nowadays, students safe in violence area is becoming to a huge problems, from the survey- National Youth Risk Behavior Survey we find that the sexual and dating violence rate is increasing during the past few years.For the willing that we try to reduce the risk of dating and sexual violence, we are going to build some programs and publish them to the society especially the schools to protect our teenagers. As we know that the period for students from high school to the university is a very important time to build their right social norms, we start a program called …