Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Public Health (25)
- Public Health Education and Promotion (13)
- Social and Behavioral Sciences (12)
- Community Health and Preventive Medicine (9)
- Life Sciences (7)
-
- Chemicals and Drugs (5)
- Mental and Social Health (5)
- Amino Acids, Peptides, and Proteins (4)
- Diseases (4)
- Medical Specialties (4)
- Nanotechnology (4)
- Psychology (4)
- Nanomedicine (3)
- Sociology (3)
- Women's Health (3)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (2)
- Arts and Humanities (2)
- Cancer Biology (2)
- Cell and Developmental Biology (2)
- Community Health (2)
- Education (2)
- Environmental Public Health (2)
- Family, Life Course, and Society (2)
- Health Psychology (2)
- Maternal and Child Health (2)
- Microbiology (2)
- Nursing (2)
- Oncology (2)
- Other Public Health (2)
- Keyword
-
- Hispanic (3)
- Barriers (2)
- Breast cancer (2)
- Colorectal cancer (2)
- Mentorship (2)
-
- Obesity (2)
- Sleep (2)
- Trauma (2)
- Women (2)
- 2019 (1)
- Addiction (1)
- Adhesion (1)
- Adolescent (1)
- Adolescents (1)
- Alcohol use (1)
- Annual Meeting (1)
- Appalachian region (1)
- Art (1)
- Asian Indians (1)
- Asylum (1)
- Blindness (1)
- Bodily boundaries (1)
- Body image (1)
- Bonding (1)
- Book review; One Health; Global Health (1)
- Brain (1)
- Bridging (1)
- Cancer (1)
- Cancer screening (1)
- Childhood Asthma (1)
- Publication
- Publication Type
Articles 1 - 30 of 47
Full-Text Articles in Medicine and Health Sciences
Quality Evaluation Tool For Clinician Online Continuing Medical Education, Brittany Rosen, Gary Kreps, James M. Bishop Mr., Skye L. Mcdonald
Quality Evaluation Tool For Clinician Online Continuing Medical Education, Brittany Rosen, Gary Kreps, James M. Bishop Mr., Skye L. Mcdonald
Health Behavior Research
The purpose of this study was to develop and assess an instrument evaluating the quality of online continuing medical education interventions for clinicians. A review of seminal literature for evaluating health-related websites was conducted to incorporate best practices from health education, health communication, and web-based design principles. After reviewing the literature, 12 preliminary quality indicators were developed. Two independent coders used the preliminary quality indicators to code continuing medical education interventions. Internal reliability of the preliminary indicators was calculated using the Krippendorff’s alpha coefficient. After completing the reliability testing and revising the tool, the quality evaluation framework consisted of six …
Exposure To Violence And Sleep Inadequacies Among Men And Women Living In A Shelter Setting, Pooja Agrawal, Julie Neisler, Michael S. Businelle Phd, Darla E. Kendzor Phd, Daphne C. Hernandez, Chisom Odoh, Lorraine R. Reitzel
Exposure To Violence And Sleep Inadequacies Among Men And Women Living In A Shelter Setting, Pooja Agrawal, Julie Neisler, Michael S. Businelle Phd, Darla E. Kendzor Phd, Daphne C. Hernandez, Chisom Odoh, Lorraine R. Reitzel
Health Behavior Research
Exposure to violence may explain sleep inadequacies reported by homeless adults, with women being potentially more susceptible to violence and sleep disturbances than men. This study examined the association between violence and sleep inadequacies among homeless adults and explored differences by sex. Adult participants were recruited from a shelter (n = 194; 71.1% men, Mage = 43.8+12.2). Participants self-reported victimization and/or witnessing violence (mugging, fight, and/or sexual assault) at the shelter, sleep duration (over an average 24 hours), insufficient sleep (days without sufficient rest/sleep), and unintentional daytime sleep (days with unintentional sleep) in the past month. Linear regressions …
Diet Quality As A Mediator Of The Relation Between Income-To-Poverty Ratio And Overweight/Obesity Among Adults: Moderating Effect Of Sex, Sajeevika S. Daundasekara, Nipa P. Kamdar, Ashley Dao, Anna Greer, E. Lisako J. Mckyer, Daphne C. Hernandez
Diet Quality As A Mediator Of The Relation Between Income-To-Poverty Ratio And Overweight/Obesity Among Adults: Moderating Effect Of Sex, Sajeevika S. Daundasekara, Nipa P. Kamdar, Ashley Dao, Anna Greer, E. Lisako J. Mckyer, Daphne C. Hernandez
Health Behavior Research
Poverty status influences obesity and dietary quality, and dietary quality influences obesity. How these relationships differ by sex is unclear. The current study aims were to 1) determine whether dietary quality mediates the relation between income-to-poverty ratio (IPR) and overweight/obesity (OV/OB) among men and women, separately, and 2) determine whether either of the mediated paths differs by sex. Four cycles of NHANES (2007-2014) were merged to obtain an unweighted study sample of 12,768 adults with complete data. Exposure variables included self-reported measures of IPR, Healthy Eating index (HEI) total score to measure diet quality, and sex. Direct assessment of …
Adult Food Insecurity Is Associated With Heavier Weight Preferences Among Black Women, Layton Reesor-Oyer, Nadia Garcia Marroquin, Daphne C. Hernandez
Adult Food Insecurity Is Associated With Heavier Weight Preferences Among Black Women, Layton Reesor-Oyer, Nadia Garcia Marroquin, Daphne C. Hernandez
Health Behavior Research
Food insecurity is related to overweight/obesity among women. However, it is unknown whether food insecurity impacts individuals’ desired body composition, and whether this relationship differs by race/ethnicity similar to perceived ideal weight status. This study aims to evaluate whether food insecurity is related to elevated preferred weight status (e.g., overweight/obese versus normal weight) among black, white, and Hispanic women classified as overweight/obese. Four waves of NHANES data (2007–2014) were merged and yielded a total of 907 black, 1,271 white, and 1,005 Hispanic non-pregnant adult (age 20 to 59) women classified as overweight/obese. Participants self-reported their preferred weight status, adult-level food …
Mammography Social Support For Women Living In A Midwestern City: Toward Screening Promotion Via Social Interactions, Wasantha P. Jayawardene, Mohammad R. Torabi, David K. Lohrmann, Ahmed H. Youssefagha
Mammography Social Support For Women Living In A Midwestern City: Toward Screening Promotion Via Social Interactions, Wasantha P. Jayawardene, Mohammad R. Torabi, David K. Lohrmann, Ahmed H. Youssefagha
Health Behavior Research
Notwithstanding recommendations and interventions, the percentage of 50 – 74-year-old U.S. women who reported having had a mammography in the past two years remained below target coverage. Social interactions may influence mammography rates. To measure characteristics of social interactions in a Midwestern city as they relate to social support for mammography received by women older than 40 years of age. A cross-sectional study was conducted in Bloomington, Indiana, sending mail surveys to 3,000 telephone directory addresses selected by simple random sampling. An anonymous, self-administered, closed-ended, questionnaire with eight checklist items (for demographics) and six multipart semantic differential scale items (for …
Consistency Of Reported Barriers For Colorectal Cancer Screening Among Adults Who Have Never Been Screened, Cherie Conley, Amanda J. Dillard, Constance M. Johnson, John A. Updegraff, Wei Pan, Alyssa Langenberg, Isaac Lipkus
Consistency Of Reported Barriers For Colorectal Cancer Screening Among Adults Who Have Never Been Screened, Cherie Conley, Amanda J. Dillard, Constance M. Johnson, John A. Updegraff, Wei Pan, Alyssa Langenberg, Isaac Lipkus
Health Behavior Research
Morbidity and mortality from colorectal cancer can be decreased by addressing patient barriers to colorectal cancer screening; especially among adults who have never been screened. Assessing changes in barriers over time may help practitioners better tailor interventions to address patient barriers. We assessed among adults ages 50 -75 who have never been screened for colorectal cancer (CRC) which barriers predict prospective screening. A sample of 560 adults who had never been screened, recruited from Growth for Knowledge’s online panel, completed a baseline and a six-month follow-up survey. Both surveys assessed screening barriers after an online intervention that involved conveying tailored …
Cross-Sectional Associations Of Opiate Misuse/Opioid Use Disorder Among Adults Experiencing Homelessness, Valentina Maza, Daphne C. Hernandez, Phd, Msed, Faahb, Darla E. Kendzor Phd, Michael S. Businelle Phd
Cross-Sectional Associations Of Opiate Misuse/Opioid Use Disorder Among Adults Experiencing Homelessness, Valentina Maza, Daphne C. Hernandez, Phd, Msed, Faahb, Darla E. Kendzor Phd, Michael S. Businelle Phd
Health Behavior Research
The purpose of this manuscript is to determine the prevalence of opioid misuse/opioid use disorder (OUD) among adults experiencing homelessness and describe characteristics that account for significant variance in relation to opioid misuse in those who misuse and do not misuse opioids. From six homeless shelters in Oklahoma City, adults participated in a survey about their demographics, substance use, mental health, and physical health from July to August of 2016 (n = 569). For assessing substance use, participants responded about their opioid misuse and diagnosis of OUD, current smoking status, arrests due to drug possession or driving while intoxicated, …
Health Literacy And Self-Rated Health Among Homeless Adults, Chisom Odoh Phd, Jennifer I. Vidrine Phd, Michael S. Businelle Phd, Darla E. Kendzor Phd, Pooja Agrawal, Lorraine R. Reitzel Phd
Health Literacy And Self-Rated Health Among Homeless Adults, Chisom Odoh Phd, Jennifer I. Vidrine Phd, Michael S. Businelle Phd, Darla E. Kendzor Phd, Pooja Agrawal, Lorraine R. Reitzel Phd
Health Behavior Research
Poor health literacy reduces the efficacy of behavior change interventions, hampers management of health conditions, and attenuates understanding of the prevention and treatment of diseases. Poor health literacy has also been linked to fair/poor self-rated health in domiciled samples; however, there is a paucity of studies on the relation amongst homeless adults, who bear a disproportionate burden of disease and disability and require a high level of care and access to health services. Here, we examined the association between health literacy and self-rated health among a convenience sample of homeless adults. Participants were recruited from six homeless-serving agencies in Oklahoma …
What Determines Young Adults’ Attitudes, Perceived Norms, And Perceived Behavioral Control Towards Healthy Sleep Behaviors? A Reasoned Action Approach, Paul Branscum, Katie Qualls Fay
What Determines Young Adults’ Attitudes, Perceived Norms, And Perceived Behavioral Control Towards Healthy Sleep Behaviors? A Reasoned Action Approach, Paul Branscum, Katie Qualls Fay
Health Behavior Research
A common limitation to the design of public health sleep interventions is the overall lack of using theory. Previous researchers have utilized the theory of planned behavior and the reasoned action approach (RAA) to predict healthy sleep behaviors, however much of this research was done using reflective (or generalized) measures, which alone is likely inadequate to equip health practitioners with tangible information they can use to translate theory into practice. Therefore, the purpose of this study was to use formative (or belief-based) measures of the RAA to evaluate the determinants of attitudes, perceived norms, and perceived behavioral control (PBC) of …
Food Insecurity As A Predictor Of Hurricane Exposure Among Underserved Adolescents, Katherine R. Arlinghaus, Daphne C. Hernandez, Craig Johnston
Food Insecurity As A Predictor Of Hurricane Exposure Among Underserved Adolescents, Katherine R. Arlinghaus, Daphne C. Hernandez, Craig Johnston
Health Behavior Research
Low-income populations are at increased risk for experiencing negative hurricane exposures and food insecurity. However, little is known regarding how pre-hurricane food insecurity experiences are related to youth hurricane exposure. This study examined the types of hurricane disaster exposures low-income, ethnic minority adolescents experienced during Hurricane Harvey and examined the association between food insecurity and hurricane exposure. Low-income adolescents (n = 185) were recruited from a Houston-area school district. Two days before the hurricane, food insecurity was assessed. Adolescents with at least one affirmative answer on the 9-item USDA Child Food Security Survey Module were classified as food insecure. …
Negative School Experiences And Pain Reliever Misuse Among A National Adolescent Sample, Kelsi J. Wood, Keith A. King, Rebecca A. Vidourek, Ashley L. Merianos
Negative School Experiences And Pain Reliever Misuse Among A National Adolescent Sample, Kelsi J. Wood, Keith A. King, Rebecca A. Vidourek, Ashley L. Merianos
Health Behavior Research
A recent public health concern is the nonmedical use of prescription drugs among U.S. adolescents. The purpose of this study was to determine the relationship between negative school experiences and lifetime and past year pain reliever misuse among adolescents enrolled in high school nationwide. A secondary analysis was performed using the National Survey on Drug Use and Health 2017 data. Participants included 8,337 adolescents enrolled in 9th -12th grades. A total of 6.0% of high school students reported they had misused pain relievers in their lifetime, and 3.9% reported they had misused pain relievers during the past year. …
Using The Theory Of Triadic Influence To Examine Correlates Of Positive Drug Expectancies Among Hispanic Adolescents, Wura Jacobs, Lauren Bartoszek, Jennifer Unger
Using The Theory Of Triadic Influence To Examine Correlates Of Positive Drug Expectancies Among Hispanic Adolescents, Wura Jacobs, Lauren Bartoszek, Jennifer Unger
Health Behavior Research
This study employs the Theory of Triadic Influence (TTI) which articulates the different variables that influence health-related behaviors into streams of influence—intrapersonal, social, and cultural—to better understand factors that influence positive drug use expectancies (PDE) among Hispanic adolescents. Data for the study came from Project RED, which included 1,963 high school students in Southern California. The relationships between participants’ drug expectancies and different streams of influence were examined using regression analysis. Participants were mostly females (54.2%); with a mean age of 17.13 years. Controlling for other covariates, there were no cultural stream variables associated with PDE (Model 1). Model 2, …
The Spread And Utility Of Social Network Analysis Across A Group Of Health Behavior Researchers, Megan S. Patterson, Tyler Prochnow Med, Patricia Goodson
The Spread And Utility Of Social Network Analysis Across A Group Of Health Behavior Researchers, Megan S. Patterson, Tyler Prochnow Med, Patricia Goodson
Health Behavior Research
Social network analysis (SNA), both as theory and methodology, is a powerful framework for delimiting and studying health behaviors. Using SNA allows scholars to answer new research questions, innovatively investigate the social and systemic contexts of health and behavior, and collaborate on multi- or inter-disciplinary projects. As a result, SNA is growing in popularity within health behavior research and practice. Despite SNA’s contribution and appeal, few health behavior researchers and practitioners have access to formal SNA education; much of the current training efforts occur outside degree-granting curricula. Therefore, the aims of this paper were to: 1) assess the diffusion of …
Advancing Academic Careers Through Formal Professional Mentorship: The Research Scholars Mentorship Program (Rsmp), Matthew Lee Smith, Lorraine R. Reitzel, Jessica M. Rath, Lisa Benz Scott, David Wyatt Seal
Advancing Academic Careers Through Formal Professional Mentorship: The Research Scholars Mentorship Program (Rsmp), Matthew Lee Smith, Lorraine R. Reitzel, Jessica M. Rath, Lisa Benz Scott, David Wyatt Seal
Health Behavior Research
Mentorship is an essential component of professional development for young and emerging scholars. In partnership with the Kellogg Health Scholars Program, the American Academy of Health Behavior (AAHB) developed the 12-month Research Scholars Mentorship Program (RSMP) as a mechanism to facilitate high-quality mentorship interactions among junior and seasoned investigators within the Academy. This article provides a rationale, history, and description of the RSMP, as well as the collective scholarly achievements of the Cohorts and future directions. To date, 44 Pairs have initiated or completed the program. Products written and submitted by the Pairs during the 12-month mentorship period have included …
Mentoring The Next Generation Of Health Professionals: A Mentor-The-Mentor Approach, Andrea L. Demaria, Stephanie Meier, Jaziel L. Ramos-Ortiz
Mentoring The Next Generation Of Health Professionals: A Mentor-The-Mentor Approach, Andrea L. Demaria, Stephanie Meier, Jaziel L. Ramos-Ortiz
Health Behavior Research
The purpose of this commentary is to share team-based mentoring strategies used for successful interdisciplinary research team productivity and sustainability. This commentary lists and describes the top ten considerations for building a productive mentor-the-mentor approach, inspired by the train-the-trainer method. The approach promotes reciprocal training and individualized experiences, while producing positive professional and personal outcomes. We pinpoint how relationship-building rooted in passion and clear communication, explicit expectations and regular celebrations, and routine paired with a bit of play enhances productivity and encourages future health professionals to emerge as leaders in the field.
Strategies For Successful Long-Distance Mentoring, Annie Nguyen, Scott Rhodes
Strategies For Successful Long-Distance Mentoring, Annie Nguyen, Scott Rhodes
Health Behavior Research
Mentorship offers benefits to both the mentee and mentor in terms of professional development and productivity. It can take many forms and is not limited to mentee-mentor pairs that are employed at the same institution. Mentoring relationships that span institutions offer an avenue for expanding one’s professional network beyond the local environment. We refer to this type of mentorship as “long-distance mentoring.” We offer four critical strategies and reflections for successful long-distance mentoring based on our experience in the AAHB Research Scholars Mentorship Program.
The Mechanism Of Theory-Based Hiv Behavioral Intervention On Condom Use Among Rural-To-Urban Migrants In China: The Mediating Roles Of Hiv Knowledge And Condom Use Self-Efficacy, Chengbo Zeng, Xiaoming Li, Hongfei Du, Danhua Lin
The Mechanism Of Theory-Based Hiv Behavioral Intervention On Condom Use Among Rural-To-Urban Migrants In China: The Mediating Roles Of Hiv Knowledge And Condom Use Self-Efficacy, Chengbo Zeng, Xiaoming Li, Hongfei Du, Danhua Lin
Health Behavior Research
Previous studies have suggested HIV knowledge and self-efficacy are important cognitive factors that might influence condom use behaviors. However, data were limited regarding their mediating effects on condom use during behavioral interventions. This study examined the mechanistic roles of these two factors on the effect of a community-based intervention aiming to increase condom use behaviors and intention among young rural-to-urban migrants in China. Data were derived from a community-based HIV behavioral intervention trial among 639 young sexually active rural-to-urban migrants in Beijing, China. Path analyses were used to examine the direct and indirect effects of the intervention program on condom …
Barriers To Hiv Testing Within A Sample Of Spanish-Speaking Latinx Gay, Bisexual, And Other Men Who Have Sex With Men: Implications For Hiv Prevention And Care, Danielle N. Horridge, Timothy S. Oh, Jorge Alonzo, Lilli Mann-Jackson, Amanda E. Tanner, Eunyoung Y. Song, Benjamin D. Smart, Cornelius N. Van Dam, Logan S. Baker, Scott D. Rhodes
Barriers To Hiv Testing Within A Sample Of Spanish-Speaking Latinx Gay, Bisexual, And Other Men Who Have Sex With Men: Implications For Hiv Prevention And Care, Danielle N. Horridge, Timothy S. Oh, Jorge Alonzo, Lilli Mann-Jackson, Amanda E. Tanner, Eunyoung Y. Song, Benjamin D. Smart, Cornelius N. Van Dam, Logan S. Baker, Scott D. Rhodes
Health Behavior Research
Gay, bisexual, and other men who have sex with men (GBMSM) have higher rates of HIV infection compared to the general population in the United States, and the infection rate is growing among Latinx GBMSM, compared to a decline in most other demographic subgroups. Uptake of pre-exposure prophylaxis (PrEP), a biomedical strategy designed to reduce HIV transmission, is very low among Latinx GBMSM. HIV testing is a critical first step in the HIV prevention and care continua. We analyzed data from a community-based sample of Latinx GBMSM in the southeastern United States to identify the most common HIV testing barriers …
Contrasting Adult And Emerging Adult Women On Possible Psychosocial And Behavioral Correlates Of Short-Term Weight Loss, James J. Annesi, Ping H. Johnson
Contrasting Adult And Emerging Adult Women On Possible Psychosocial And Behavioral Correlates Of Short-Term Weight Loss, James J. Annesi, Ping H. Johnson
Health Behavior Research
Physical activity could be associated with psychosocial correlates of changes in eating behaviors required for weight loss. This field investigation assessed relationships of physical activity with early changes in psychosocial variables such as depression, fatigue, and body satisfaction; and their effect on fruit/vegetable and sweets intake and weight change. Emerging adult women from a university setting (Mage = 20.4 years, SD = 2.0; n = 36) and adult women from a community health-promotion setting (Mage = 45.6 years, SD = 7.3; n = 36), participating in the same cognitive-behavioral weight-loss program that initiated physical activity prior …
Using Complex, Multi-Sectoral Data In A Needs Assessment To Inform Future Strategies In Childhood Asthma Management, Loren Raun, David Persse, Gwendolyn Johnson, Katherine Ensor, Elizabeth Stevenson, Melissa A. Valerio, Erin K. Caton, Laura Campos, Harold J. Farber
Using Complex, Multi-Sectoral Data In A Needs Assessment To Inform Future Strategies In Childhood Asthma Management, Loren Raun, David Persse, Gwendolyn Johnson, Katherine Ensor, Elizabeth Stevenson, Melissa A. Valerio, Erin K. Caton, Laura Campos, Harold J. Farber
Health Behavior Research
The purpose of this needs assessment was to study the current state of asthma management in high-risk children in Houston, Texas to inform a theory-based approach to improving asthma management. The mixed-method assessment included multi-sectoral survey, quantitative, and geospatial data that address a range of social and community factors in family, community, home, and medical contexts. Houston Emergency Medical Services (EMS) provided ambulance-treated asthma data mapped by geographic area to identify where childhood asthma management was weakest. Texas Children’s Health Plan (TCHP) provided medication compliance rates and counts of children by zip code that TCHP considered high-risk according to claims …
The American Academy Of Health Behavior 2019 Annual Scientific Meeting: "Theory And Applications Of Multiple Health Behavior Change", Mark Reed
Health Behavior Research
The American Academy of Health Behavior (AAHB) hosted it's 19th Annual Scientific Meeting at the Westin Poinsett in Greenville, SC March 10-13, 2019. The meeting's theme was "Theory and Applications of Multiple Health Behavior Change." This publication describes the meeting theme and includes the refereed abstracts presented at the 2019 Annual Scientific Meeting.
The Ecological Paradox: Can Human Prosperity And Planetary Health Co-Exist?, Jay E. Maddock
The Ecological Paradox: Can Human Prosperity And Planetary Health Co-Exist?, Jay E. Maddock
Health Behavior Research
Over the past century, advances in public health have led to longer, healthier, and more prosperous lives. However, this rising prosperity has led to increases in consumption contributing to loss of biodiversity, climate change, air pollution, ocean acidification, and deforestation. In his new book entitled, “Survival: One Health, One Planet, One Future,” George Lueddeke examines this paradox and what can be done to ensure a sustainable planet as well as healthy human and animal populations.
Examining Multiple Health Behaviors, Julie M. Croff, Ashleigh L. Chiaf, Erica K. Crockett
Examining Multiple Health Behaviors, Julie M. Croff, Ashleigh L. Chiaf, Erica K. Crockett
Health Behavior Research
Health behaviors have been extensively studied as predictors of disease; however, these behaviors may interact and intersect to amplify or ameliorate risks of predicted disease outcomes. Breadth of study is needed to examine how single antecedents may act to influence multiple health behaviors, and how multiple health behaviors may predict other behaviors and/or interact to influence the occurrence of disease outcomes. Better understanding of how behaviors interact and impact health is necessary to identify the appropriate leverage points for the evolution of health behavior theory, and the promotion of multiple health behavior change.
Part Of Her: An Exploration Of The Bodily Boundaries Between Parent And Child And The Limits Of Personhood In Lina Meruane’S Sangre En El Ojo, Sawnie Smith
Studies in 20th & 21st Century Literature
Lina Meruane (1970-) is a contemporary Chilean author whose novels began to captivate at the turn of the twenty-first century. Her works are replete with unsettling meditations on the fragility of human flesh. And the promise of illness—its infectious potential—clings to the air in her literary worlds, such as those found in Fruta podrida (2007) and Sangre en el ojo (2012). This latter novel in particular serves as a vivid example of Meruane’s talent for writing sickly atmospheres. It is a novel saturated with bodily imagery, such as disembodied eyes, parasitic embraces, and grim sexual foreplay. All of these visuals …
Peptide Functionalized Surfactant Msns, Sonia Barrett
Peptide Functionalized Surfactant Msns, Sonia Barrett
Kansas State University Undergraduate Research Conference
Antibiotic resistance in bacteria has become a rising problem since the first antibiotic was created, further aggravated by the improper overuse to treat common infections, because of this pharmaceutical companies must keep making new and stronger antibiotics. Surfactants are plentiful and effective killers of many surface bacteria and are also varied in their structure, all have a hydrophilic head and long hydrophobic carbon chain. These long hydrophobic carbon chains can pierce through the lipid bilayers that make up bacteria cell membranes and cause cytoplasmic leakage and lysis of the cell wall, leading to cell death. One proposed surfactant is synthesized …
Heme Expression From Caulobacter Crescentus In E. Coli, Gloriana Tokgozoglu
Heme Expression From Caulobacter Crescentus In E. Coli, Gloriana Tokgozoglu
Kansas State University Undergraduate Research Conference
The focus of my research is to create a clone of a Heme transporter from Caulobacter crescentus and transformed into E. coli OKN359 and fluorescently label it so that it can detect Heme in the environment. This sensor will be combined with others in a fluorescence assay to analyze pathogenic bacteria and identify drugs that are the most effective in inhibiting their iron transport. To do so, I used Gibson cloning and made a hybrid gene, pITS27, that contains a small initial portion of an E.coli gene fepA followed by the full Caulobacter crescentus gene hutA. The initial portion of …
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Kansas State University Undergraduate Research Conference
In recent years, nanocarrier cellular therapy has been a rapidly growing area for research in the treatment of malignant and infectious diseases – most notably cancer. Conventional cancer treatment has consisted of highly toxic, highly insoluble, untargeted delivery of drugs that kill both cancerous and healthy cells. Research in the Tomich lab consists of the synthesis of Branched Amphiphilic Peptide Capsules (BAPCs), which are self-assembling peptide nanospheres composed of one or both of these branched peptide sequences: h5 and h9. These peptides possess similar molecular characteristics of phosphoglycerides but are synthesized chemically within the lab. Previous publications by the Tomich …
Comparison Of Immunohistochemistry Methods For Visualization Of Middle Eastern Respiratory Viral Antigen, Elena Carlos
Comparison Of Immunohistochemistry Methods For Visualization Of Middle Eastern Respiratory Viral Antigen, Elena Carlos
Kansas State University Undergraduate Research Conference
Middle Eastern respiratory syndrome (MERS), caused by MERS coronavirus (MERS-CoV) first appeared in Saudi Arabia in 2012. Although there have been less than 2,400 cases reported, the case fatality rate is 35%. Dromedary camels are the known host animal for the virus. However, they are difficult to manage experimental animals. In a recent study, alpacas proved to be a suitable experimental animal to further characterize MERS-CoV infection. Our work is part of a wider project focused on studying the efficacy of MERS-CoV antigen and RNA labeling in infected alpaca tissues, when these tissues are preserved in novel modular alcohol fixatives …
Therapeutic Peptide Sequences And Gatekeepers Loaded With Mesoporous Silica Nanoparticles, Dursitu Hassen
Therapeutic Peptide Sequences And Gatekeepers Loaded With Mesoporous Silica Nanoparticles, Dursitu Hassen
Kansas State University Undergraduate Research Conference
The research community is developing and looking into new ways of effectively delivering anti-cancer treatment. According to National Cancer Institute over 1.5 million new cases of cancer are predicted in the United States, just alone in 2018. The major hurdles that have been identified by scientists are finding mechanisms that assist in decreasing the side effects of cancer treatment and to increase the effectiveness of the drug. In our lab, a highly toxic peptide sequence, SA-K6L9-AS is encapsulated in MSNs (mesoporous silica nanoparticles) and capped with a gatekeeper. The function of a gatekeeper is preventing the …
Design Of Sensors For In-Vivo Detection Of Cancer Related Enzymes, Laura Soto
Design Of Sensors For In-Vivo Detection Of Cancer Related Enzymes, Laura Soto
Kansas State University Undergraduate Research Conference
Cancer continues to be among the leading causes of death worldwide. In 2018, there were approximately 9.6 million cancer deaths, just in the United States alone, there were 1.7 million new cancer cases and 600,000 deaths. That is why, there is an urgent need for better ways to battle cancer. Therefore, the goal of this project is to create a nanobiosensor which would have T1 and T2 based imaging capabilities to measure cancer enzymatic activity. The diagnostic tool would be useful to differentiate between benign and malignant tumors in-vivo and to quantify the effect of cancer treatments, such …