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Ipilimumab Activity In Advanced Uveal Melanoma: A Pooled Analysis, Muhammad A. Khattak, Elin Gray
Ipilimumab Activity In Advanced Uveal Melanoma: A Pooled Analysis, Muhammad A. Khattak, Elin Gray
Research outputs 2014 to 2021
Background
Uveal Melanoma is a rare tumour that displays different clinical behavior and molecular features compared with cutaneous melanoma. It is generally resistant to systemic therapy and there is no current standard effective therapy to treat patients with advanced disease.
Patients and methods
We searched Medline, PubMed, EMBASE and major oncology conference abstracts from the past 5 years to identify relevant studies evaluating ipilimumab monotherapy in uveal melanoma. Data were extracted on ipilimumab dose, sample size, Objective Response Rate (ORR), Progression Free Survival (PFS), median Overall Survival (mOS), Disease Control Rate (DCR), 1 year Overall Survival (1yrOS) and 2 year …