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- Stem cell transplantation; Whole exome sequencing; Dynamical systems; Graft versus host disease; minor histocompatibility antigens; Antigen presentation; Vector - Operator Matrices; Alloreactivity; Donor T cell: T cell antigen response simulation; HLA Antigen presentation; Tissue antigen expression; HLA binding affinity; Stochastic; Randomness in clinical outcome (1)
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Articles 1 - 10 of 10
Full-Text Articles in Medicine and Health Sciences
The Large-Scale Organization Of Shape Processing In The Ventral And Dorsal Pathways, Erez Freud, Jody C. Culham, David C. Plaut, Marlene Behrmann
The Large-Scale Organization Of Shape Processing In The Ventral And Dorsal Pathways, Erez Freud, Jody C. Culham, David C. Plaut, Marlene Behrmann
Brain and Mind Institute Researchers' Publications
Although shape perception is considered a function of the ventral visual pathway, evidence suggests that the dorsal pathway also derives shape-based representations. In two psychophysics and neuroimaging experiments, we characterized the response properties, topographical organization and perceptual relevance of these representations. In both pathways, shape sensitivity increased from early visual cortex to extrastriate cortex but then decreased in anterior regions. Moreover, the lateral aspect of the ventral pathway and posterior regions of the dorsal pathway were sensitive to the availability of fundamental shape properties, even for unrecognizable images. This apparent representational similarity between the posterior-dorsal and lateral-ventral regions was corroborated …
Unfolding Suicidality, Samantha N. Danko
Effect Of Early Tranexamic Acid Administration On Mortality, Hysterectomy, And Other Morbidities In Women With Post-Partum Haemorrhage (Woman): An International, Randomised, Double-Blind, Placebo-Controlled Trial, Haleema Shakur-Still, Ian Roberts, Rizwana Chaudhri, Bukola Fawole, Mohamed El-Sheikh, Adesina L. Akintan, Zahida Qureshi, Hussein Kidanto, Bellington Vwalika, Abdulfetah Abdulkadir
Effect Of Early Tranexamic Acid Administration On Mortality, Hysterectomy, And Other Morbidities In Women With Post-Partum Haemorrhage (Woman): An International, Randomised, Double-Blind, Placebo-Controlled Trial, Haleema Shakur-Still, Ian Roberts, Rizwana Chaudhri, Bukola Fawole, Mohamed El-Sheikh, Adesina L. Akintan, Zahida Qureshi, Hussein Kidanto, Bellington Vwalika, Abdulfetah Abdulkadir
Faculty of Health Sciences, East Africa
Background Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early administration of tranexamic acid on death, hysterectomy, and other relevant outcomes in women with post-partum haemorrhage.
Methods In this randomised, double-blind, placebo-controlled trial, we recruited women aged 16 years and older with a clinical diagnosis of post-partum haemorrhage after a vaginal birth or caesarean section from 193 hospitals in 21 countries. We randomly assigned women to receive either 1 g intravenous tranexamic acid or matching placebo in addition …
The Effect Of Current Low Back Pain On Volitional Preemptive Abdominal Activation During A Loaded Forward Reach Activity, V. R. Nagar, T. L. Hooper, G. S. Dedrick, J. M. Brismee, M. K. Mcgalliard, P. S. Sizer
The Effect Of Current Low Back Pain On Volitional Preemptive Abdominal Activation During A Loaded Forward Reach Activity, V. R. Nagar, T. L. Hooper, G. S. Dedrick, J. M. Brismee, M. K. Mcgalliard, P. S. Sizer
Physical Therapy
No abstract provided.
Attenuation Of Postoperative Adhesions Using A Modeled Manual Therapy (Data Files), Geoffrey M. Bove, Susan L. Chapelle, Katherine E. Hanlon, Michael P. Diamond, David J. Mokler
Attenuation Of Postoperative Adhesions Using A Modeled Manual Therapy (Data Files), Geoffrey M. Bove, Susan L. Chapelle, Katherine E. Hanlon, Michael P. Diamond, David J. Mokler
Biomedical Sciences Faculty Publications
These files include data and figures utilized to research and communicate the following:
Postoperative adhesions are pathological attachments that develop between abdominopelvic structures following surgery. Considered unavoidable and ubiquitous, postoperative adhesions lead to bowel obstructions, infertility, pain, and reoperations, and represent a substantial health care challenge. Despite over a century of research, no preventive treatment exists. Based on the hypothesis that postoperative adhesions develop from a lack of movement of the abdominopelvic organs, we proposed a relatively simple treatment approach using a modified manual therapy technique that mobilizes abdominopelvic structures in the immediate postoperative period while they are otherwise rendered …
Dynamical System Modeling To Simulate Donor T Cell Response To Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness In Alloreactivity Incidence Following Stem Cell Transplantation, Vishal Koparde, Badar Abdul Razzaq, Tara Suntum, Roy Sabo, Allison Scalora, Myrna Serrano, Max Jameson-Lee, Charles Hall, David Kobulnicky, Nihar Sheth, Juliana Feltz, Daniel Contaifer, Dayanjan Wijesinghe, Jason Reed, Catherine Roberts, Rehan Qayyum, Gregory Buck, Michael Neale, Amir Toor
Dynamical System Modeling To Simulate Donor T Cell Response To Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness In Alloreactivity Incidence Following Stem Cell Transplantation, Vishal Koparde, Badar Abdul Razzaq, Tara Suntum, Roy Sabo, Allison Scalora, Myrna Serrano, Max Jameson-Lee, Charles Hall, David Kobulnicky, Nihar Sheth, Juliana Feltz, Daniel Contaifer, Dayanjan Wijesinghe, Jason Reed, Catherine Roberts, Rehan Qayyum, Gregory Buck, Michael Neale, Amir Toor
Massey Comprehensive Cancer Center Data
Quantitative relationship between the magnitude of variation in minor histocompatibility antigens (mHA) and graft versus host disease (GVHD) pathophysiology in stem cell transplant (SCT) donor-recipient pairs (DRP) is not established. In order to elucidate this relationship, whole exome sequencing (WES) was performed on 27 HLA matched related (MRD), & 50 unrelated donors (URD), to identify nonsynonymous single nucleotide polymorphisms (SNPs). An average 2,463 SNPs were identified in MRD, and 4,287 in URD DRP (p
Saving Lives And Reducing Harm: A Cauti Reduction Program, K. A. Scanlon, C. M. Wells, L. Woolforde, A. Khameraj, J. Baumgarten
Saving Lives And Reducing Harm: A Cauti Reduction Program, K. A. Scanlon, C. M. Wells, L. Woolforde, A. Khameraj, J. Baumgarten
Journal Articles
No abstract provided.
Accuracy Of Full-Arch Scans Using Intraoral And Extraoral Scanners: An In Vitro Study Using A New Method Of Evaluation, Jonas Muallah, Christian Wesemann, Roxana Nowak, Jan Robben, James Mah, Peter Pospiech, Axel Bumann
Accuracy Of Full-Arch Scans Using Intraoral And Extraoral Scanners: An In Vitro Study Using A New Method Of Evaluation, Jonas Muallah, Christian Wesemann, Roxana Nowak, Jan Robben, James Mah, Peter Pospiech, Axel Bumann
Dental Medicine Faculty Publications
The aim of this study was to compare the accuracy of six intraoral scanners as regards clinically relevant distances using a new method of evaluation. An additional objective was to compare intraoral scanners with the indirect digitization of model scanners. A resin master model was created by 3D printing and drilled in five places to reflect the following distances: intermolar width (IMW), intercanine width (ICW), and arch length (AL). To determine a gold standard, the distances were measured with a coordinate measuring instrument (Zeiss O-Inspect 422). The master model was scanned 37 times with the following intraoral scanners: Apollo DI …
Making Marble Powder Waste Profitable By Using Nano-Tio2 Surface Modification For Air Quality Improvement Applications, Yaxiong Ji, Xing Rong, Hong Zhong, Yuanhao Wang, Shifeng Wang, Lin Lu
Making Marble Powder Waste Profitable By Using Nano-Tio2 Surface Modification For Air Quality Improvement Applications, Yaxiong Ji, Xing Rong, Hong Zhong, Yuanhao Wang, Shifeng Wang, Lin Lu
Faculty of Science & Technology (THEi)
We report a brand new recycling route of waste marble powder, by means of surface modification with homemade nano-TiO2 particles to produce low cost coating materials for the application in air quality improvement. The as-prepared nano-TiO2 in anatase phase exhibits excellent photocatalytic characteristic, reflected by the high degradation rate of over 95% of methylene blue within 6 hours of UV irradiation. The prepared coating consisting of nano-TiO2 clad marble powder was tested by monitoring the decomposition rate of formaldehyde gas. A high degradation efficiency of about 95% within 9 hours of illumination is achieved, demonstrating a promising potential for removing …
Silencing Science.Pptx, Kai Hung
Silencing Science.Pptx, Kai Hung
Faculty Research & Creative Activity
This is a non-peer reviewed teaching resource.