Medicine and Health Sciences Commons^™

Producing A Subunit Vaccine For Porcine Epidemic Diarrhea Virus, Zayn Khamis

Electronic Thesis and Dissertation Repository

Porcine epidemic diarrhea virus (PEDv) causes disease and mortality to piglets worldwide. Most vaccines used to combat the disease have been ineffective live attenuated virus vaccines. The goal of this project was to produce a plant-made subunit vaccine based off the membrane protein of the virus. This is the first time this protein has been produced in plants. An elastin-like polypeptide fusion membrane protein accumulated up to 0.8 mg/g of fresh leaf weight when transiently expressed in Nicotiana benthamiana. Virus-like particles were also produced for the first time for PEDv, and were able to form with just the membrane …

Evaluation Of Several Pre-Clinical Tools For Identifying Characteristics Associated With Limb Bone Fracture In Thoroughbred Racehorses, Anthony Nicholas Corsten

Open Access Theses

Catastrophic skeletal fractures in racehorses are devastating not only to the animals, owners and trainers, but also to the perception of the sport in the public eye. The majority of these fatal accidents are unlikely to be due to chance, but are rather an end result failure from stress fractures. Stress fractures are overuse injuries resulting from an accumulation of bone tissue damage over time. Because stress fractures are pathological, it is possible that overt fractures can be predicted and prevented. In this study, third metacarpals (MC3) from 33 thoroughbred racehorse comprised of 8 non-fractured controls and 25 horses that …

The Impact Of Tickling Rats On Human-Animal Interactions And Rat Welfare, Megan Renee Lafollette

Open Access Theses

Rats initially fear humans which can lead to negative affect, poor welfare, and difficult handling. Also, modeling and measuring positive affect states in rats can pose an additional challenge. Heterospecific play, or “tickling,” is a handling habituation technique that mimics rat rough-and-tumble play that is being used to study positive affect. It can also be used to reduce fear of human, improve welfare, and elicit a positive affect state. However, current studies implementing the technique in laboratory rats use a wide variety of protocols to achieve differential results. Unlike in laboratory environment, pet store rats experience high levels of novelty …

Follicular Dynamics In Insulin Resistant Mares, Julio Cesar Prado

Masters Theses

Obesity and insulin resistance have been linked to prolonged interovulatory period, aberrations in the estrous cycle, and continuous reproductive activity during the non-breeding season. EMS has been determined to influence the intrafollicular environment of mare ovaries. In humans, insulin resistance has been linked to polycystic ovaries as part of Polycystic Ovarian Syndrome (PCOS). A study was conducted to determine 1) the impact of insulin resistance on follicle growth and size at ovulation, and 2) whether predicted ovulatory follicles respond to hCG administration in Insulin-resistant (IR) mares. Mares were selected for the study based on insulin sensitivity and separated into an …

Epidemiology Of Toxoplasma Gondii And A Survey Of Other Parasites In The West Indian Manatee (Trichechus Manatus), Heidi Lynn Wyrosdick

Masters Theses

Toxoplasma gondii is a protozoan parasite of felids reported to cause morbidity and mortality in the two subspecies of the West Indian Manatee (Trichechus manatus): the Antillean manatee (Trichechus manatus manatus) in Puerto Rico and the Florida manatee (Trichechus manatus latirostris). Sera or plasma (n=343) were collected from live-capture T. m. latirostris through the US Geological Survey (USGS) manatee health assessment program and serosanguinous fluid (n=10) were collected from necropsies conducted by the Marine Mammal Pathobiology Laboratory (MMPL). Additionally, serum or serosanguinous fluid samples (n=5) were collected from rehabilitated or necropsied T. m. manatus …

Detección A Través De Pcr De Escherichia Coli Enterotoxigénicas En Terneras De 1 A 15 Días De Edad En Un Hato Lechero Ubicado En La Sabana De Bogotá En El Municipio De Madrid, Cundinamarca, José Mauricio Romero Vanegas

Medicina Veterinaria

No abstract provided.

Evaluating The Physical Welfare Of Dogs In Commercial Breeding Facilities In The United States, Moriah J. Hurt

Open Access Theses

Despite high levels of public concern, the state of commercial breeding (CB) dog welfare is largely unknown. Therefore, this study aimed to characterize the physical welfare of dogs in CB facilities and their environment in Indiana. This study specifically aimed 1) to characterize dog foot health in CB facilities as a function of the length of time dogs were housed on a given flooring substrate, 2) to characterize visual dog body cleanliness and visual kennel cleanliness as a function of the flooring substrate, 3) to determine the efficacy of kennel cleaning procedures and 4) to characterize the dog dental and …

Influence Of Dietary Component Manipulation And Feed Management Strategies On Growth And Rumen Development Of Weaned Dairy Heifers, Tana Shea Dennis

Open Access Dissertations

Well-developed replacement heifers provide a central foundation for the continued success of the dairy industry. Emphasis on improving pre-weaned calf nutrition has predominated in the industry, but opportunities exist to improve post-weaning heifer nutrition and management. We aimed to evaluate common feed management strategies seen in the industry and their effects on growth, feed efficiency (G:F), and rumen development of calves from birth to 8 mo of age using pen- and individually-fed animal trials. Little information exists regarding post-weaning performance and rumen development of calves fed conventional or high planes of nutrition pre-weaning; therefore, we evaluated two milk replacer feeding …

Evaluating The Prevalence And Effectiveness Of Breed-Specific Legislation, Felicia E. Trembath

Open Access Dissertations

Dog bites pose a persistent public health problem, which some jurisdictions pass breed-specific legislation (BSL) to address. However, very little non-anecdotal evidence regarding the efficacy of BSL has been presented. Currently, BSL research is hampered by the absence of standard terminology, an established prevalence, or a scientific consensus on its effectiveness. The purpose of this study is to propose standardized terminology for BSL, establish the prevalence of each type of BSL in the USA, and conduct a systematic review of the effectiveness of BSL.

After review of terminology currently in use, as well as review of the regulatory actions of …

Training Needs Of Licensed Veterinary Technicians Employed In Augusta County, Virginia, Jeannie Kay Skelton

OTS Master's Level Projects & Papers

The problem of this study was to determine the training needs of Licensed Veterinary Technicians in Augusta County, Virginia to improve their knowledge and skills in the veterinary field. The study was guided by research questions that were developed to determine what the training needs of Licensed Veterinary Technicians are, what their preferred method is for obtaining continuing education credits, what methods they use to obtain new knowledge and skills, and if on the job training is effective. A survey was designed to determine what training methods are being used, what is preferred, and what training is needed in the …

Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, Katherine E. Kelly

Senior Honors Projects, 2010-2019

Keratoconjunctivitis sicca (KCS), the deficiency of tears also known as dry eye, is a prevalent disease that affects both humans and canines. The current treatment for dye eye, cyclosporine (Restatis®), only provides temporary relief, is often associated with discomfort and is inconsistently effective. Lacritin is a naturally occurring tear glycoprotein secreted from the human and canine lacrimal glands. It has been shown that lacritin stimulates basal tearing in rabbits when applied topically. This study characterized the amount and form of lacritin found in the tears of dogs with healthy and dry eyes—information which may be applied to the development of …

Evaluation And Selection Of A Bacillus Based Direct-Fed Microbial Candidate For In Situ Enzyme Production To Improve Gut Health Integrity, Bone Quality And Growth Performance In Poultry, Juan David Latorre Cardenas

Graduate Theses and Dissertations

During the last decade, the increasing interest in renewable energy sources has been changing the distribution of corn utilization from human and animal consumption to biofuel production, leading to a continuous rise in feed costs of livestock diets. Therefore, alternative feed ingredients such as distillers dried grains with solubles (DDGS), as well as cereals like wheat, barley, and sorghum have become part of the feed matrix to maintain or reduce production costs. However, these raw materials often contain a higher concentration of antinutritional factors in comparison to corn, including non-starch polysaccharides (NSP) which increase digesta viscosity and reduce nutrient absorption …

Studies On The Prevalence And Control Of Parasitic Helminths In "Natural" Laying Hens, Brittany R. Weir

Animal Science Undergraduate Honors Theses

One societal trend that has been gaining much traction and popularity since the 21^st century began is “organic” and/or “natural” food products. In 1999, the global market accounted for $15.2 billion dollars worth of organic food and drink, compared to the market in 2014 where we consumed $80 billion dollars worth (Willer et. al, 2016). With “natural” production of food animals however, “natural” parasite transmission may be a consequence. To that end, this experiment examines the prevalence of helminths in 110 “natural” laying hens from three regional farms and the efficacies of fenbendazole, piperazine, and levamisole on what should …

Identification Of Feline Tritrichomonas Foetus Surface Epitopes: Putative Targets For Development Of A Novel Diagnostic Test For Feline Trichomonosis, Emily Nissa Gould

Masters Theses

BACKGROUND: Tritrichomonas foetus (T. foetus) is a flagellated protozoa that infects the distal ileum and proximal colon of domestic cats and also induces reproductive failure in cattle. Although feline trichomonosis is recognized to have a global prevalence of up to 30%, it still poses a diagnostic and therapeutic challenge to veterinarians; thus, there is a need for both improved diagnostics and therapeutics. Despite differing organ tropism between genotypes, evidence exists for conserved virulence factors between feline and bovine T. foetus. Two epitopes (1.15 and 1.17) of the bovine T. foetus glycosylated surface antigen 1.15-1.17 have been found …

Identifying Genetic Factors In Streptococcus Uberis That Enable Evasion Of The Host Immune Response, Alexis Christine Burnham

Chancellor’s Honors Program Projects

No abstract provided.

Expansion, Characterization, Differentiation, And Visualization Of Mc 3t3-E1 Preosteoblast Cells: An In Vitro Model To Study Bone Healing And Stem Cell-Mediated Regeneration, Jakob T. Samsel, Madhu Dhar, Austin Bow, Tom Masi

Chancellor’s Honors Program Projects

No abstract provided.

Can Parasitized Lambs Self-Medicate Through Preferred Consumption Of Sericea Lespedeza Pellets?, Mallory Alicia Garcia

Honors Theses

No abstract provided.

Evaluation Of Negative Energy And Mineral Balance In Periparturient Holstein-Friesian Cattle, Ameer Ahmed Abdelhameed

Open Access Dissertations

Most cows experience a state of negative energy and mineral balance during the periparturient period. This imbalance is a major problem in the dairy industry and it is more frequently seen in multiparous cattle due to their high milk production. A large amount of fat and protein is mobilized in order to address the energy deficit during the periparturient period. The ability to accurately monitor energetics and electrolytes status using accurate, rapid, and low cost point-of-care instruments will assist in optimizing animal health and productivity.

This dissertation contains three studies that evaluated point-of-care instruments for measuring blood and plasma glucose, …

Evaluación Preliminar De La Recuperación Muscular Basada En El Lactato Del Caballo De Rejoneo, Jeny Castillo, Andrés Felipe González

Medicina Veterinaria

El nivel de lactato sérico en los músculos de los caballos varía cuando pasan de una condición de reposo a una condición de esfuerzo físico o de estrés, y regresa a su nivel inicial después de que ha transcurrido un determinado tiempo desde que se restablece su condición de reposo (Arias, Echavarría, Coral, Acosta, & Zuluaga, 2006). Si el animal es sometido a esfuerzos excesivos, podría presentar acidosis y de esta manera afectar el flujo energético muscular del caballo (Castejón, Muñoz, Agüera, Gómez, & Essén, 1997). Por otro lado, la actividad de rejoneo se practica en algunas ciudades y poblaciones …

The Effects Of Acidified Pepsin On Porcine Vocal Fold Tissue: Developing A Porcine Model Of Laryngopharyngeal Reflux Disease, Abigail Cox Durkes

Open Access Dissertations

Approximately 7.5 million Americans are affected by a voice disorder. In the last year, 7.2% of people missed one or more days of work due to a voice problem. For professional voice users, such as teachers, the rate increases to 20% and an annual cost of $2.5 billion. Voice disorders are complex and multi-faceted, as well as difficult to diagnose and treat. Prospective animal studies are necessary to study the pathophysiology of voice disorders, optimize our understanding of laryngeal pathology, and improve treatment outcomes. The pig provides a unique opportunity to test hypotheses relating to laryngeal disease because porcine vocal …

Determinación Radiológica De Parámetros Posicionales De La Falange Distal En El Caballo Criollo Colombiano De Paso De La Sabana De Bogotá, Guillermo Andrés Cardona Villalobos

Maestría en Ciencias Veterinarias

La importancia económica y relevancia poblacional del caballo criollo colombiano de paso (CCC) en Cundinamarca hacen que sea vital la generación de estudios enfocados específicamente a este tipo de caballos. Debido a la falta de reportes escritos acerca de ciertos parámetros fisiológicos de estos animales, los médicos veterinarios que trabajan con el CCC deben basar sus diagnósticos en literatura escrita con base en caballos diferentes, tanto en su disciplina como en sus características fenotípicas, que implican un reto aún mayor para el diagnóstico de ciertas entidades patológicas. Teniendo esto en cuenta, se hace trascendental la determinación de los rangos posicionales …

Evaluación Del Potencial Nematófago De Los Hongos Arthrobotrys Musiformis Y Arthrobotrys Oligospora En Bovinos, Diana Catherine Flórez Castañeda

Medicina Veterinaria

La creciente demanda mundial de alimentos inocuos de origen animal para el consumo humano, la presentación de resistencia a los antihelmínticos y la contaminación ambiental por residuos de estos compuestos, son razones suficientes para plantear nuevas estrategias de control de nematodos gastrointestinales (NGI) en los sistemas de producción bovinos. Una alternativa promisoria y ampliamente estudiada en diferentes partes del mundo es el control biológico utilizando hongos nematófagos, considerados uno de los principales enemigos naturales de los nematodos, y por lo tanto, una opción viable para controlar las fases de vida libre de los NGI que parasitan rumiantes. Teniendo en cuenta …

Análisis Del Comportamiento De Los Parámetros Hematológicos En Caballos Que Compiten En Carreras De Enduro A 2640 M.S.N.M, Marlly Carolina Mesa Rojas

Medicina Veterinaria

Esta investigación tuvo como objetivo estudiar la variación en el conteo de eritrocitos, Hematocrito (Hto), hemoglobina (Hb), y el análisis del leucograma en este estudio se utilizaron 12 equinos de raza árabe que practican carreras de enduro a los cuales se les tomaron muestras sanguíneas pre y pos- ejercicio en Bojacá, Cundinamarca. Como metodología se tomaron muestras sanguíneas directamente de la vena yugular de los equinos, sometidos a la carrera de enduro en 3 momentos específicos: antes de iniciar la carrera (T0), inmediatamente finalizado la carrera (T1) y a la hora post-ejercicio (T2). Los resultados obtenidos fueron depurados y analizados …

Prácticas Asociadas Al Bienestar Animal De Bovinos En Una Planta De Beneficio Del Municipio De Villavicencio, Paula Andrea González Roa

Medicina Veterinaria

Bienestar animal es el trato humanitario brindado a los animales, con el fin de disminuir el estrés, la tensión, el sufrimiento, los traumatismos y el dolor desde su crianza hasta su sacrificio, siendo responsabilidad de los actores involucrados en la cadena productiva. Las actividades previas al beneficio, embarque, desembarque, pesaje, movilización a corrales de reposo y a beneficio, implican una interacción entre hombre, animal y ambiente, donde el desconocimiento por parte del personal encargado del manejo, así como la infraestructura inadecuada, contribuyen a aumentar el estrés y causar lesiones en los animales, como consecuencia se disminuye la calidad e inocuidad …

Bienestar Animal Y Sus Beneficios En La Cadena Cárnica Bovina, Jorge David Duarte Forero

Medicina Veterinaria

No abstract provided.

Estudio Para La Creación De Una Tienda En Línea Para Servicios Veterinarios Y Productos Para Mascotas Delimitado A Bogotá, Jessica Chaki

Medicina Veterinaria

Se realizó el planteamiento preliminar de una empresa llamada “The Animal Shop”, que es una tienda en línea que busca facilitar a los propietarios de mascotas la adquisición de productos y servicios veterinarios para sus animales. La empresa se realizó en Colombia, donde se desarrolla lentamente la apropiación del uso de internet para compras de productos y servicios veterinarios que benefician a las mascotas. Con una investigación de mercados inicial, se intentará explorar la disposición de los dueños de mascotas para comprar los productos principales y adquirir servicios veterinarios por una página de internet. Finalmente, se proponen los lineamientos preliminares …

Reporte De Caso: Tumor De Las Células De La Granulosa En La Yegua Criolla Colombiana, Juan Camilo Abello Duque

Medicina Veterinaria

No abstract provided.

Estudio Retrospectivo De La Influencia Del Sexo Del Feto En El Volumen De Producción De Vacas Lecheras De La Raza Holstein En El Municipio De San Pedro De Los Milagros, Antioquia, Colombia, Carlos Daniel Barreto Arciniegas, Diego Alejandro Pardo Barón

Medicina Veterinaria

La producción láctea a nivel mundial y específicamente en Colombia, corresponde a una de las principales actividades económicas. Debido a la importante demanda de leche y productos lácteos a nivel mundial y la escasa oferta de los mismos en Colombia, y dadas las actuales condiciones de introducción de Colombia en mercados internacionales, la industria lechera colombiana requiere cada vez mayor competitividad por lo que es necesario que tanto el número de animales como el volumen de producción en los hatos de ganadería especializada se incremente de manera significativa para así beneficiar en mayor parte a los productores lecheros pero también …

Evaluación Del Porcentaje De Preñez En Ovejas Por Inseminación Con Semen Congelado Y Semen Congelado Diluido Con Tcm 199, Pamela González Murcia, Jairo Andrés Martínez

Medicina Veterinaria

El objetivo del presente trabajo fue evaluar el porcentaje de preñez realizando inseminación artificial tras-vaginal con semen congelado y con semen congelado diluido y con el TCM 199 como parte del diluyente, para evaluar a viabilidad del semen y su eficacia para la preñez de las ovejas. El trabajo se realizó en la finca CRIADERO LA FRONTERA ubicada en Tenjo, Cundinamarca ubicado en la Provincia de Sabana Centro a 37 km de Bogotá, con ovejas con cruce entre criollas y Katahdin. Se realizó en dos grupos cada uno de 30 ovejas, que fueron inseminadas aleatoriamente, 15 con semen congelado y …

Reporte De Caso; Diarrea Viral Bovina En El Municipio De Aguazul Casanare, Marjorie Natalia Godoy Diaz

Medicina Veterinaria

La ganadería bovina es la primera actividad económica del departamento de Casanare, con el 70% de su población dedicada a la cría, expuesta a diversas enfermedades poco conocidas por los ganaderos, como es el caso de las afecciones reproductivas, que causan pérdidas por abortos, crías débiles y prolongado intervalo entre partos. En el municipio de Aguazul, Casanare, los ganaderos reportan dicha sintomatología que tiene relación con Diarrea Viral Bovina, pero desconocen su causa y la manera de prevenirla, controlarla y de implementar un esquema de vacunación adecuado. Por ende, se detectó la necesidad inicial de hacer seguimiento a reportes de …