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Mifepristone Utilization In Cushing’S From Large Bilateral Adrenal Adenoma Prior To Surgery, Vasudev Magaji, Sarah Park, Katie Mastoris, Maura Bucciarelli, Scott Beman
Mifepristone Utilization In Cushing’S From Large Bilateral Adrenal Adenoma Prior To Surgery, Vasudev Magaji, Sarah Park, Katie Mastoris, Maura Bucciarelli, Scott Beman
Vasudev G Magaji MD, MS
Utilization of mifepristone was described to mitigate hypercortisolism from bilateral adrenal Cushing’s syndrome. A 47-year-old female on abdominal pain evaluation with CT was found to have a 5.4 × 1.7 × 4.9 cm right adrenal nodule and a 4.3 × 2.9 × 3.3 cm left adrenal nodule with calcification on CT scan with each having density of -3 Housefield units. She had hypercortisolism with testing revealing high urine free cortisol, unsuppressed cortisol on 1 mg and 8 mg overnight dexamethasone suppression testing, high 11 pm salivary cortisol × 2 along with elevated random cortisol and undetectable ACTH. Her DHEA-S, plasma …