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Full-Text Articles in Medicine and Health Sciences

Transcending Microbial Source Tracking Techniques Across Geographic Borders: An Examination Of Human And Animal Microbiomes And The Integration Of Molecular Approaches In Pathogen Surveillance In Brazil And The United States, Amber Mae Koskey Dec 2013

Transcending Microbial Source Tracking Techniques Across Geographic Borders: An Examination Of Human And Animal Microbiomes And The Integration Of Molecular Approaches In Pathogen Surveillance In Brazil And The United States, Amber Mae Koskey

Theses and Dissertations

Waterborne illnesses, attributed to the ingestion or contact with contaminated water, present a significant global health concern. Surface water sources can be impacted by wide array of pollution inputs, but fecal pollution generates the most significant and acute threat to human health. Therefore, the detection of fecal bacteria in surface water sources remains an important public health objective. Current surface water monitoring employs the use of fecal indicator bacteria (FIB) including E. coli and enterococci as proxies for pathogenic organisms carried in fecal pollution. These traditional indicators, detected by culture-based microbiological methods, do not discriminate fecal sources from another. New …


Clinical Phenotypes And Abcc6 Gene Mutations In Brazilian Families With Pseudoxanthoma Elasticum., Caroline Silvério Faria, Qiaoli Li, Haitao Guo, Jouni Uitto, Sylvia Satomi Takeno, Marilia De Arruda Cardoso Smith, Dertia Villalba Freire-Maia Nov 2013

Clinical Phenotypes And Abcc6 Gene Mutations In Brazilian Families With Pseudoxanthoma Elasticum., Caroline Silvério Faria, Qiaoli Li, Haitao Guo, Jouni Uitto, Sylvia Satomi Takeno, Marilia De Arruda Cardoso Smith, Dertia Villalba Freire-Maia

Department of Dermatology and Cutaneous Biology Faculty Papers

Pseudoxanthoma elasticum (PXE; OMIM 264800) manifests with characteristic skin lesions of yellowish papules which coalesce into plaques of inelastic and leathery skin on the predilection sites (1). The ocular findings consist of angioid streaks, choroidal neovascularization and subretinal hemorrhages resulting in loss of visual acuity and occasional blindness. Cardiovascular problems include hypertension, intermittent claudication, and occasional myocardial infarcts and stroke. The prevalence of PXE is estimated to be in the range of 1:50,000-70,000 and to be more frequent in females than in males. The diagnosis can be challenging to clinicians due to late-onset of clinical manifestations and considerable heterogeneity. PXE …


Humanitarianism And The Anthropology Of Hunger, Kate Klein Jul 2013

Humanitarianism And The Anthropology Of Hunger, Kate Klein

Undergraduate Theses—Unrestricted

While the early view of hunger as the product of a world population too large to sustain has largely been eliminated, and the mainstream international community has come to accept that food insecurity results from issues of distribution rather than an insufficient global food supply, the emphasis on biotechnology in agriculture, humanitarianism in international aid, and social justice in international human rights law in the contemporary era has contributed to other barriers that prevent hunger alleviation.

In this thesis, I argue that these previous contemporary developments have had the capacity to hide hunger. My analysis of technology and humanitarian aid …


Setting Up The Longitudinal Study For Adult Health (Elsa-Brasil), Paulo A. Lotufo Jan 2013

Setting Up The Longitudinal Study For Adult Health (Elsa-Brasil), Paulo A. Lotufo

Paulo A Lotufo

Baseline data collection of the Brazilian Longitudinal Study for Adult Health (ELSA-Brasil) was complete by December 2010. A cohort of 15,105 subjects has been followed up on incident events at six study sites for three years. The ELSA-Brasil is remarkable for its large sample size and wide variety of data collected to investigate biological and social determinants of cardiovascular diseases and diabetes mellitus in adults in Brazil. A group of Brazilian experts in chronic noncommunicable disease research started planning this study project in 2004. It was launched at a meeting on August 20 to 21, 2004 held at the Universidade …


Delivering Genetic Education And Genetic Counseling For Rare Diseases In Rural Brazil, A.X. Acosta, K Abe-Sandes, R Giugliani, Alan H. Bittles Jan 2013

Delivering Genetic Education And Genetic Counseling For Rare Diseases In Rural Brazil, A.X. Acosta, K Abe-Sandes, R Giugliani, Alan H. Bittles

Research outputs 2013

Brazil is the largest country in Latin America, with an ethnically diverse, Portuguese-speaking and predominantly Roman Catholic population of some 194 million. Universal health care is provided under the Federal Unified Health System (Sistema Único de Saúde) but, as in many other middle and low income countries, access to medical genetics services is limited in rural and remote regions of the country. Since there is no formally recognized Genetic Counseling profession, genetic counseling is provided by physicians, trained either in medical genetics or a related clinical discipline. A comprehensive medical genetics program has been established in Monte Santo, an inland …


Polycyclic Evolution Of Camboriú Complex Migmatites, Santa Catarina, Southern Brazil: Integrated Hf Isotopic And U-Pb Age Zircon Evidence Of Episodic Reworking Of A Mesoarchean Juvenile Crust, Miguel Angelo Stipp Basei, Mario Da Costa Campos Neto, Angela Pacheco Lopes, Allen Phillip Nutman, Dunyi Liu, Kei Sato Jan 2013

Polycyclic Evolution Of Camboriú Complex Migmatites, Santa Catarina, Southern Brazil: Integrated Hf Isotopic And U-Pb Age Zircon Evidence Of Episodic Reworking Of A Mesoarchean Juvenile Crust, Miguel Angelo Stipp Basei, Mario Da Costa Campos Neto, Angela Pacheco Lopes, Allen Phillip Nutman, Dunyi Liu, Kei Sato

Faculty of Science, Medicine and Health - Papers: part A

The Camboriú Complex is the only gneissic-migmatitic inlier within the Neoproterozoic Brusque Group supracrustal rocks, in the northernmost part of the Dom Feliciano Belt, southern Brazil. It comprises the Morro do Boi migmatites and the diatexitic Ponta do Cabeço Granite. Zircon U-Pb dating of migmatites and associated granitic neosomes shows that crustal evolution started in the Paleo- Mesoarchean (3.3-3.0 Ga), continued with events through the Neoarchean and Paleoproterozoic and ended in the Neoproterozoic (0.64-0.61 Ga). Integration of zircon Hf isotopic data and U-Pb ages indicate that juvenile crustal accretion was restricted to the Archean and that afterwards intracrustal reworking predominated. …