Medicine and Health Sciences Commons^™

Synthesis Of Novel Aromatic Quinols For Colon And Renal Cancers, Bradley J. Davey, Tae Soo Jo, Pradip K. Bhowmik

Undergraduate Research Opportunities Program (UROP)

Colon Cancer: The third most common cancer in USA. More than 1 million Americans currently living with colon cancer. 148,810 new cases expected in 2010. 50,000 deaths annually.

Renal Cancer: Approximately 58,000 people diagnosed in USA annually. Seventh most common cancer and tenth most common cause of cancer related death in men.

Aromatic quinols have demonstrated in vitro antitumor activity. Three heteroaromatic quinols show antitumor activity.

Construction And Use Of A Calorimeter To Estimate The Anaerobic Contributions To Metabolism, Mark S. Burger, Frank Van Breukelen

Undergraduate Research Opportunities Program (UROP)

Metabolism is derived from the Greek word metabole which translates to change. Metabolism is the sum total of chemical reactions that take place in an organism. Some reactions are exothermic (heat-producing) whereas others are endothermic (heat-absorbing). By measuring heat production (calorimetry), one can estimate metabolic rate. Historically, such measurements of direct calorimetry were difficult. As a result, most studies utilize indirect calorimetry wherein oxygen consumption and/or carbon dioxide production are measured. One limitation to this approach is that anaerobic metabolism is ignored. No commercially-available calorimeter is available for whole animal metabolic studies. We hypothesized that small rodent hibernators may experience …

Y-Aminobutyric Acid Inhibits Synergistic Interleukin-6 Release And Increases Intracellular Cytokine Content In C6 Astrocytoma Cells In Vitro, Daniella Sandoval, Becky M. Hess, Bryan L. Spangelo

Undergraduate Research Opportunities Program (UROP)

Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by memory loss and is the most common cause of dementia. It is has been hypothesized that pro-inflammatory cytokines induce the inflammation that is believed to be the cause of the neuronal death that is associated with AD. γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the Central Nervous System possessing membrane hyperpolarization or depolarization activities. A decline in GABA may enhance cytokine release in Alzheimer’s disease resulting in neuroinflammation. Therefore, we investigated the GABA-mediated suppression of the synergistic release of interleukin-6 (IL-6) induced by interleukin 1- (IL-1) and …

Undergraduate Research Opportunities Program 2010, University Of Nevada, Las Vegas

Undergraduate Research Opportunities Program (UROP)

The Undergraduate Research Opportunities Program (UROP) cultivates and supports research partnerships and invites undergraduates to work as the junior colleagues of faculty. The program offers the opportunity to work on cutting edge research—whether you join established research projects or pursue your own ideas. As participants, undergraduates engage in each phase of standard research activity: developing research plans, writing proposals, conducting research, analyzing data. and presenting research results in oral and written form. The projects take place over the summer, and research can be done in any academic department or interdisciplinary laboratory. Projects can last for an entire semester, and many …

Deaths In Custody In Nevada, 2001-2006, Brian R. Brehman, Terance D. Miethe, Timothy C. Hart

Graduate Research Symposium (GCUA) (2010 - 2017)

A large number of prisoners die each year while under the custody of the state. These deaths include prisoners who are executed under state laws and other deaths in custody from a variety of causes. Nationally, 18,550 individuals died in the custody of a state prison between 2001 and 2006. This state data brief examines deaths in custody in Nevada prisons and jails and compares them to national averages. This report summarizes the prevalence rates for deaths in custody, changes in these custody deaths over time, the cause of these deaths, and compares custody deaths in Clark County jail to …

Defining Intimacy In Diverse Asian Cultures, Blendine Hawkins, Katherine Herlein

Graduate Research Symposium (GCUA) (2010 - 2017)

America has continued to diversify as a nation, welcoming people from every race, culture and continent. The US Census Bureau (2004) reported that there were 13.5 million Asians in America and these numbers are increasing (US Census Bureau, 2004). This indicates that there is a greater demand for competent and effective mental health care to meet the needs of this heterogeneous group. Asian Americans can be best helped by a therapist who is sensitive, knowledgeable and has an understanding about the core values which are present in many Asian cultures. There are limited resources and treatment guides for this population …

The Portrayal Of Schizophrenia In Television: An Experiment Assessing How Viewer Attitudes Are Affected, Lindsey Jo Hand, Paul Traudt

Graduate Research Symposium (GCUA) (2010 - 2017)

Portrayals of schizophrenia in the media have been found to be very negative in nature. This study is an attempt to take research in this area a step further by conducting an experiment measuring attitudes of viewers toward schizophrenia before and after viewing an episode of Law and Order: Special Victims Unit in which a man with schizophrenia is depicted as a dangerous sexual deviant. Participants were given a pretest, viewed the television show and then were given a post-test. The post-test and pretest are identical and consist of questions from the Community Attitudes on Mental Illness (CAMI) scale and …

Evaluating The Comprehensiveness Of Youth Access To Tobacco Legislation, Richard Clark

Graduate Research Symposium (GCUA) (2010 - 2017)

The deadly effects of smoking have been well documented since the 1960s. As laws and ordinances have been instituted at the state level, various measures have been developed in an attempt to measure both the comprehensiveness and effectiveness of such restrictions. This paper seeks to build on the rating systems already developed that currently look at individual laws by developing an overall rating scale of state level smoking restrictions and their effectiveness over time. Results of the overall rating scale will be shared along with recommendations for future research.

Therapeutic Alliance And Client Satisfaction From The Client’S Perspective, Colleen Peterson, Armeda Stevenson, Katherine M. Hertlein, Stephen Fife

Graduate Research Symposium (GCUA) (2010 - 2017)

This was the second phase of a two phase mixed methodology study. Presented is the qualitative portion consisting of semi-structured phone interviews conducted with past clients in order to examine the relationship of the therapeutic alliance and client satisfaction with client retention and termination status.Findings were classified into three main categories: therapist characteristics, treatment structural characteristics and process characteristics.