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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2009

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UCHC Articles - Research

Endophenotype

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Full-Text Articles in Medicine and Health Sciences

Priming Deficiency In Male Subjects At Risk For Alcoholism: The N4 During A Lexical Decision Task, Lance O. Bauer Dec 2009

Priming Deficiency In Male Subjects At Risk For Alcoholism: The N4 During A Lexical Decision Task, Lance O. Bauer

UCHC Articles - Research

Abstract

Background

While there is extensive literature on the relationship between the P3 component of event-related potentials (ERPs) and risk for alcoholism, there are few published studies regarding other potentially important ERP components. One important candidate is the N4(00) component in the context of semantic processing, as abnormalities in this component have been reported for adult alcoholics.

Method

A semantic priming task was administered to non-alcohol dependent male offspring (18 to 25 years) of alcoholic fathers [high risk (HR) n=23] and non-alcoholic fathers [low risk (LR) n=28], to study whether the two groups differ in terms of the N4 component. …