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Full-Text Articles in Medicine and Health Sciences
Itraconazole-Induced Torsade De Pointes In A Patient Receiving Methadone Substitution Therapy, Noorzurani Robson Associate Prof. Dr., B. Vicknasingam, S. Narayanan
Itraconazole-Induced Torsade De Pointes In A Patient Receiving Methadone Substitution Therapy, Noorzurani Robson Associate Prof. Dr., B. Vicknasingam, S. Narayanan
Associate Prof. Dr. Noorzurani Robson
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings. This case report highlights the risk of Torsade de Pointes, a life-threatening cardiac arrhythmia, in a heroin-dependent patient receiving methadone substitution therapy who was prescribed itraconazole for vaginal thrush. The patient presented to the accident and emergency department for chest discomfort and an episode of syncope following two doses of itraconazole (200 mg). Electrocardiogram monitoring at the accident and emergency department showed prolonged rate-corrected QT interval leading to Torsade de …
Public Health H1n1 Response Research Protocol, Glen Mays
Public Health H1n1 Response Research Protocol, Glen Mays
Glen Mays
This research protocol was developed to analyze local variation in the public health response to the 2009 H1N1 influenza outbreak in the United States. The protocol was fielded in North Carolina and Kentucky through practice-based research networks (PBRNs) operating in these states.
Opportunities For Comparative Research In Public Health Pbrns: A Baseline Analysis Of Local Practice Settings, Glen P. Mays, Sharla A. Smith
Opportunities For Comparative Research In Public Health Pbrns: A Baseline Analysis Of Local Practice Settings, Glen P. Mays, Sharla A. Smith
Glen Mays
This anaysis describes the organizational and operational characteristics of local public health agencies participating in an initial cohort of five (5) public health PBRNs in the U.S. We examine variation in practice settings within and between PBRNs; compare practice settings to state and national norms; and identify opportunities for comparative research that can be conducted through PBRNs
Initial Research And Evaluation Concepts For Public Health Pbrns, Glen Mays
Initial Research And Evaluation Concepts For Public Health Pbrns, Glen Mays
Glen Mays
Initial research and evaluation activities of the Public Health PBRN Program are intended to provide a descriptive characterization of networks during their early stages of development. This descriptive ‘network analysis’ will provide a baseline for tracking changes in network structure and function over time. The information generated through these activities is intended to be useful for a variety of audiences, including current grantees and others interested in developing or expanding public health PBRNs, as well as policy and practice stakeholders interested in using the evidence and insight to be produced through PBRNs.
Start-Up Activities For Public Health Pbrns, Glen Mays
Start-Up Activities For Public Health Pbrns, Glen Mays
Glen Mays
Launching a successful public health practice-based research network requires a planned approach to developing the necessary infrastructure, relationships, and scientific direction.