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Full-Text Articles in Medicine and Health Sciences

In-Vivo Delivery Of Dna Vaccines Using Metallo-Lipid Nanoparticles, Clarissa Sara Gomez Jan 2008

In-Vivo Delivery Of Dna Vaccines Using Metallo-Lipid Nanoparticles, Clarissa Sara Gomez

Open Access Theses & Dissertations

There has been a rapidly growing area of research in the design and synthesis of molecules that self-organize in water to form functional nanosystems and due to the high interest in the area metal ligand complexes were tested as drug delivery systems with a Leishmania vaccine. Herein, we present the design, synthesis and functional activity of Cu(II) and Zn(II) complexes that self-assemble in water to form spherical nanoscale structures that exhibit an affinity to bind DNA and deliver it into eukaryotic cells with a high percent efficiency in-vitro. In order to assess the effectiveness of these nanoparticles to deliver DNA …


Theory Of Planned Behavior Constructs As Mediators Of Behavior Change Associated With A Brief Alcohol Intervention, Denise Servo Jan 2008

Theory Of Planned Behavior Constructs As Mediators Of Behavior Change Associated With A Brief Alcohol Intervention, Denise Servo

Open Access Theses & Dissertations

This study examined the Theory of Planned Behavior constructs (attitudes, subjective norms, perceived behavioral control [PBC], and behavioral intentions) as mediators of changes in alcohol consumption and alcohol-related problems in a longitudinal sample of 206 college students. The Brief Alcohol Screening and Intervention for College Students (BASICS) is a program designed to curb risky alcohol consumption and its related consequences among college students. Eligible students completed a baseline assessment battery at assessment and again six months after participating in BASICS. The AUDIT (Alcohol Use Disorders Identification Test) assessed alcohol consumption and the RAPI (Rutgers Alcohol Problem Inventory) assessed alcohol-related problems. …


Evaluation Of A Nutrition Program Targeting Child Care Centers, Kendra Witt Jan 2008

Evaluation Of A Nutrition Program Targeting Child Care Centers, Kendra Witt

Open Access Theses & Dissertations

Color Me Healthy (CMH) is an interactive nutrition program designed for preschool aged children in child care settings. The current study examined if CMH increases the consumption of fruit and vegetables. Child care centers were randomly assigned to one of two conditions; children (n=165) in ten centers received CMH and children (n=98) in seven centers acted as controls. Consumption of fruit and vegetable snacks was assessed at baseline, one week post-intervention and 3 months post-intervention. Hierarchical linear modeling determined that group assignment was the only significant predictor of fruit and vegetable consumption. Children who were exposed to the CMH program …