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Full-Text Articles in Medicine and Health Sciences
Argininosuccinic Acidemia: A Casereport, Chih-Wei Lin, Huey-Jen Lay, I-Ju Chen
Argininosuccinic Acidemia: A Casereport, Chih-Wei Lin, Huey-Jen Lay, I-Ju Chen
Rehabilitation Practice and Science
Urea cycle disorder (UCD) is one of inborn error diseases. Citrullinemia is the most common disease (1/57000) among them, followed by argininosuccinic acidemia (ASA) (1/70000). The common characteristic of UCD is hyperammonemia induced by the abnormal liver function. Common symptoms at the onset of diseases include altered consciousness, respiratory insufficiency and seizures. Developmental delay, mental retardation, cerebral palsy, and learning disability are common findings in long-term follow-ups. In this report, we give an account of a patient with ASA. Besides the aforementioned symptoms and long-term sequelae, this patient also has the problem of ataxia. However, the patient's conditions and developments …
Bone Mineral Density In Subjects With Cerebral Palsy: A Preliminary Study In Taiwan, Hsin-Chi Wu, Ming-Chuan Lin, Yi-Shiung Horng, Hong-Yi Chen, Kwang-Hwa Chang
Bone Mineral Density In Subjects With Cerebral Palsy: A Preliminary Study In Taiwan, Hsin-Chi Wu, Ming-Chuan Lin, Yi-Shiung Horng, Hong-Yi Chen, Kwang-Hwa Chang
Rehabilitation Practice and Science
Objective: Children with cerebral palsy (CP) have complicated disabilities, and also have the tendency to suffer from osteoporotic fractures. The aim of this study was to explore the bone mineral density (BMD) and to estimate the fracture rate in Taiwanese CP subjects.Materials and methods: To study the BMD and its related factors in 28 Taiwanese CP subjects (16 males, 12 females; age range, 2-24 years; mean age, 9.8 years), we evaluated their BMD in the lumbar spine (LS-BMD) with dual energy x-ray absorptiometry, clinical characteristics, biochemical bone metabolism-related factors, and nutritional status. The fracture rate was evaluated during a three-year …
Botulinum Toxin Type A Treatment For Drooling In Taiwanese Children With Cerebral Palsy: Three Casereports, Yu-Ching Lin, I-Ling Lin, Yu-Te Chiu, Jeng-Yi Shieh
Botulinum Toxin Type A Treatment For Drooling In Taiwanese Children With Cerebral Palsy: Three Casereports, Yu-Ching Lin, I-Ling Lin, Yu-Te Chiu, Jeng-Yi Shieh
Rehabilitation Practice and Science
Botulinum toxin is a promising treatment option for the management of drooling in patients with cerebral palsy. However, the effect of botulinum toxin type A in treating drooling of Taiwanese children with cerebral palsy has not been reported thus far. We injected single dose botulinum toxin into bilateral parotid glands of three children with cerebral palsy, and followed the results over a 9-month period. Drooling improved in all three patients without significant adverse effects during follow up. There were individual differences in terms of efficacy and duration of effect. Two patients had longer duration of effect than that reported in …
Modified Constraint-Induced Movement Therapy In Spastic Cerebral Palsy: A Pilot Study, Hsuan-Ju Lin, Ching-Yi Wu, Chia-Ling Chen
Modified Constraint-Induced Movement Therapy In Spastic Cerebral Palsy: A Pilot Study, Hsuan-Ju Lin, Ching-Yi Wu, Chia-Ling Chen
Rehabilitation Practice and Science
Children with spastic cerebral palsy (CP) usually exhibit motor deficits and limited daily activities. Studies in recent years indicated that constraint-induced movement therapy (CIMT) might improve motor performance in CP patients. Combining kinematic analysis with clinical assessments, this study investigated the effect of modified CIMT (mCIMT) in four children with spastic CP immediately and one month after treatment. During the 3-week intervention, subjects underwent task-related training using the affected hand with restraint of the unaffected hand.The experimental results revealed significant improvements of the affected hand in use frequency, movement quality, grasping pattern, and bimanual coordination, both immediately and one month …