Medicine and Health Sciences Commons^™

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Ii. Management Of Radiation-Induced Caries, W. L. Chai, W.C. Ngeow, R. Ramli, R. A. Rahman

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral complications after radiation therapy. The management of xerostomia has been reviewed in Part I of this series. In this article, the management of dental caries, a sequalae of xerostomia following radiation therapy is reviewed. …

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part I. Management Of Xerostomia, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they receive radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. Part I of this series reviews the management of xerostomia. The management of the effect of xerostomia to the dentition/oral cavity is discussed in Part II. © 2006 Elsevier. …

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part V. Management Of Mucositis, W.C. Ngeow, W. L. Chai, R. A. Rahman, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. The second last part of this series reviews and discusses the management of complication that commonly occur to the oral mucosa, i.e. mucositis. © 2006 Elsevier. All rights reserved.

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Vi. Management Of Opportunistic Infections, W.C. Ngeow, W. L. Chai, R. Ramli, R. A. Rahman

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Where possible, pretreatment dental assessment shall be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally for radiation therapy. Because of this, they succumb to complicated oral adverse effects after radiation therapy. The last part of this series reviews the opportunistic infections that can occur to the perioral structure. Their management is briefly discussed. © 2006 Elsevier. All rights reserved.

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iv. Management Of Osteoradionecrosis, R. Ramli, W.C. Ngeow, R. A. Rahman, W. L. Chai

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Pretreatment dental assessment should be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally and, as a result, they succumb to complicated oral adverse effects after radiation therapy. Osteoradionecrosis (ORN) is a severe debilitating condition that impairs healing due to reduction in vascularity and osteocyte population in the affected bone. This article reviews methods of treatment used to treat ORN such …

Transient Loss Of Power Of Accommodation In 1 Eye Following Inferior Alveolar Nerve Block: Report Of 2 Cases, W.C. Ngeow, C. K. Shim, W. L. Chai

Wei Cheong Ngeow

Unintended intravascular injection from inferior alveolar nerve blocks can result in frustrating distant complications affecting such structures as the middle ear and eyes. Possible complications affecting the eyes include blurring of vision, diplopia, mydriasis, palpebral ptosis and amaurosis ( temporary or permanent). In this article, we present a complication that has been reported only rarely. Two patients developed transient loss of power of accommodation of the eye resulting in blurred vision after routine inferior alveolar nerve blocks on the ipsilateral side. Clear vision returned within 10 - 15 minutes after completion of the blocks. The possible explanation for this phenomenon …

Managing Complications Of Radiation Therapy In Head And Neck Cancer Patients: Part Iii. Provision Of Dentures, R. A. Rahman, W.C. Ngeow, W. L. Chai, R. Ramli

Wei Cheong Ngeow

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Pretreatment dental assessment should be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally and, as a result, they succumb to complicated oral adverse effects after radiation therapy. The management of radiation-induced caries, a sequelae of xerostomia has been reviewed in Part II of this series. In this article, the management of difficulty with dentures, another sequelae of xerostomia following radiation …

Histopathologic Findings And Assessment Of Cervical Lymph Node Metastasis In Oral Squamous Cell Carcinoma Of Malaysian Patients, Ismail S. B., Rosnah Binti Zain, Kipli N. P., Abraham T., Ismail M. S., Rahman Z. A. A., Prepageran N., Jalaludin M. A. B.

Prof. Dr. Rosnah Binti Zain

Purpose: To evaluate some histopathologic parameters and relate with the occurrence of cervical lymph node metastasis in oral squamous cell carcinoma (OSCC) in Malaysian patients. Methods: A total of 44 cases of OSCC resected were included. The resected specimens were examined for the OSCC type, degree of differentiation, pattern of invasion (at the tumour invasive front), greatest dimension and the depth of stromal invasion. Where there is no neck resection, the clinical nodal status was obtained from the Oral Cancer database maintained at the University of Malaya Oral Cancer Research and Coordinating Centre (UM-OCRCC) while the histopathologic data were obtained …

Immunoexpression Of Prb And Egfr Using Tissue Microarray (Tma) Technique - A Preliminary Study, Kipli N. P., Cheong C. S., Rosnah Binti Zain, Hamid S., Lim K. P., Abraham T., Ismail M. S., Hussaini H. M.

Prof. Dr. Rosnah Binti Zain

Purpose: To assess the expression of pRb and EGFR in oral epithelial lesions using TMA technique. Methods: Paraffin embedded specimens were selected from the archives of the Diagnostic Laboratories at the Faculty of Dentistry, University of Malaya and Universiti Kebangsaan Malaysia. Selected epithelial areas were cored and developed into tissue microarray blocks. A total of 32 samples for pRb and 50 samples for EGFR were analysed using immunohistochemical techniques. Results: Abnormal pRb staining (1+ or less) was seen in 80% (8/10) OSCC, 38.5% (5/13) dysplastic and 22.2% (2/9) normal/hyperplastic epithelium. Positive EGFR staining was observed in 25/35 (71.4%) OSCC cases …

Expression Of Human B-Defensin-3 In Oral Squamous Cell Carcinoma Using Tissue Microarray - A Preliminary Study, Hussaini H. M., Lim P. K., Rahman R. A., Abraham T., Cheong C. S., Rosnah Binti Zain, Ismail M. S., Nam A. N.

Prof. Dr. Rosnah Binti Zain

Purpose: Human b-Defensin (hBDs) is an epithelial origin, cationic antimicrobial peptides. Their expression is reported in oral mucosa, gingiva and salivary glands. However, their protective role is not well understood. It has been suggested that bacterial and viral infection are an important factors in the process of carcinogenesis. This study investigated the expression of hBD-3 in oral squamous cells carcinoma (OSCC). Methods: 29 OSCC and 23 samples of normal and dysplastic tissues were obtained from Oral Pathology diagnostic laboratory, faculty of Dentistry, UKM and UM. The tissues were arrayed and the expression of hBD-3 was analysed using immunohistochemistry technique. Results: …

The Effects Of Some Methacrylate Monomers Used As Liquid Component On Tensile And Flexural Strengths Of A Poly (Methyl Methacrylate) Denture Base Resin., Selda Keskin

No abstract provided.

Disposable Carrier For Retrograde Fillings, W.C. Ngeow, W. L. Chai

Wei Cheong Ngeow

Commercially available retrograde filling carriers are delicate and easily damaged by pressure. In addition, they are difficult to clean and keep free from blockage. This report describes a simple and easy technique for transforming a standard disposable hypodermic syringe and needle into a disposable carrier for retrograde fillings. © 2006 Asian Association of Oral and Maxillofacial Surgeons.

Immunoexpression Of Prb And Egfr Using Tissue Microarray (Tma) Technique - A Preliminary Study, Kipli N. P., Cheong C. S., Rosnah Binti Zain, Hamid S., Lim K. P., Abraham T., Ismail M. S., Hussaini H. M.

Prof. Dr. Rosnah Binti Zain

Purpose: To assess the expression of pRb and EGFR in oral epithelial lesions using TMA technique. Methods: Paraffin embedded specimens were selected from the archives of the Diagnostic Laboratories at the Faculty of Dentistry, University of Malaya and Universiti Kebangsaan Malaysia. Selected epithelial areas were cored and developed into tissue microarray blocks. A total of 32 samples for pRb and 50 samples for EGFR were analysed using immunohistochemical techniques. Results: Abnormal pRb staining (1+ or less) was seen in 80% (8/10) OSCC, 38.5% (5/13) dysplastic and 22.2% (2/9) normal/hyperplastic epithelium. Positive EGFR staining was observed in 25/35 (71.4%) OSCC cases …

Effect Of Mouthrinses On Surface Microhardness Of Selected Dental Composites, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Objective: To compare the surface microhardness of composites(Spectrum®TPH, Filtek™Z350, Ceram•X mono and Ceram•X duo-enamel shade) before and after immersion in alcohol containing mouthrinses (Listerine), alcohol-free mouthrinses (Oral-B) and experimental herbal mouthrinses based on plant extract (mouthrinses X, Y and Z). Methods: 60 disc-shaped specimens of approximately 10mm x 2mm were perpared from various composites using perspex split mould and was cured for 40 seconds. The irradiated surface was polished using Sof-Lex pop-on polishing discs. The specimens were randomly divided to 6 groups. Microhardness was recorded before immersion (control group) using a load of 200g for 15 seconds using Vickers microhardness …

Shear Bond Strength Of Orthodontic Adhesives On Different Tooth Types: An In Vitro Study, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Introduction: Owing to the variety of materials and methods employed, comparison of the results and findings from bonding studies is difficult. Until recently, several types of teeth have been used in published research papers as a substrate in orthodontic bonding research including bovine incisors, fresh and rebonded human premolars. Objectives: The purpose of this study was to compare the shear bond strength of an adhesive bonded to different tooth surfaces (human premolar, bovine incisor and rebonded human premolar). Methods: Two groups of thirty premolar teeth and one group of bovine incisors had brackets attached in a standardized manner using Transbond …

Multiple Intelligences And Academic Performance Among Malaysian Undergraduate Dental Students, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Objectives: To identify the nature of multiple intelligences among dental students and investigate the relationship between these intelligences and performance in the various skill areas of dentistry. Methods: Sixty-one final year dental students at the Faculty of Dentistry, University of Malaya in Malaysia were administered a Multiple Intelligence Inventory [(MII), David Larear, 1991)] after their final written examinations. MII comprised 80 4-point likert items assessing eight types of multiple intelligences: Verbal/Linguistic, Visual Spatial, Logical Mathematical, Musical Rhythmic, Intra Personal, Body Kinesthetic, Inter Personal and Naturalist. These intelligences were correlated with six academic performance scores: Amalgam Class II, Composite, Crown & …

Investigating Examiner Consistency In Criterion-Based Assessment Using Rasch Measurement, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

In the implementation of criterion-based assessment some disparities in the interpretation of the assessment criteria have been observed.Therefore it is essential that a standardization exercise be carried out to ensure equitable and fair assessment. Objectives: The purpose of the study was to evaluate inter-examiner variability and examiners' internal consistency in applying a criterion-based assessment. Method: The subjects consisted of 9 full-time staff of the Department of Conservative Dentistry, University of Malaya, 4 part-time staff and 2 postgraduate students. One buccally-approached and one palatally-approached Class III cavity preparation were assessed according to a set of criteria developed by the department. Both …