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Associations In The Course Of Personality Disorders And Axis I Disorders Over Time, M. Tracie Shea, Robert L. Stout, Shirley Yen, Maria E. Pagano, Andrew E. Skodol, Leslie C. Morey, John G. Gunderson, Thomas H. Mcglashan, Carlos M. Grilo, Charles A. Sanislow, Donna S. Bender, Mary C. Zanarini

Charles A. Sanislow, Ph.D.

In this study, the authors examined time-varying associations between schizotypal (STPD), borderline (BPD), avoidant (AVPD), or obsessive-compulsive (OCPD) personality disorders and co-occurring Axis I disorders in 544 adult participants from the Collaborative Longitudinal Personality Disorders Study. The authors tested predictions of specific longitudinal associations derived from a model of crosscutting psychobiological dimensions (L. J. Siever & K. L. Davis, 1991) with participants with the relevant Axis I disorders. The authors assessed participants at baseline and at 6-, 12-, and 24-month follow-up evaluations. BPD showed significant longitudinal associations with major depressive disorder and posttraumatic stress disorder. AVPD was significantly associated with …

Temporal Coherence Of Criteria For Four Personality Disorders, Leslie C. Morey, Andrew E. Skodol, Carlos M. Grilo, Charles A. Sanislow, Mary C. Zanarini, M. Tracie Shea, John G. Gunderson, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

This study sought to investigate the coherence of changes observed in diagnostic criteria for borderline, schizotypal, obsessive-compulsive, and avoidant personality disorders. Five hundred, forty-nine patients were independently evaluated 2 years apart, and correlations of observed changes in each diagnostic criterion with changes in other criteria were examined to determine if there was within-syndrome consistency in these changes. The observed changes in criteria were consistent within syndrome (median alpha = 0.72 across 4 disorders), and reasonably specific to that syndrome relative to the other disorders. The results support the validity of these criterion sets as representing coherent syndromes.

Major Depressive Disorder And Borderline Personality Disorder Revisited: Longitudinal Interactions, John G. Gunderson, Leslie C. Morey, Robert L. Stout, Andrew E. Skodol, M. Tracie Shea, Thomas H. Mcglashan, Mary C. Zanarini, Carlos M. Grilo, Charles A. Sanislow, Shirley Yen, Maria T. Daversa, Donna S. Bender

Charles A. Sanislow, Ph.D.

BACKGROUND: This report investigates the longitudinal association of changes in major depressive disorder (MDD) and borderline personality disorder.

METHOD: A DSM-IV-diagnosed sample of 161 patients with borderline personality disorder who have been followed with repeated measures at 6, 12, 24, and 36 months are investigated to see whether those with co-occurring MDD differ at baseline and in their course. Proportional hazard regression and cross-lagged panel analyses are used to demonstrate whether changes in the course of either disorder have predictable effects on the course of the other.

RESULTS: The rate of remissions of borderline personality disorder was not affected by …

The Longitudinal Relationship Of Personality Traits And Disorders, Megan B. Warner, Leslie C. Morey, John F. Finch, John G. Gunderson, Andrew E. Skodol, Charles A. Sanislow, M. Tracie Shea, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Personality disorders are presumed to be stable because of underlying stable and maladaptive personality traits, but while previous research has demonstrated a link between personality traits and personality disorders cross-sectionally, personality disorders and personality traits have not been linked longitudinally. This study explores the extent to which relevant personality traits are stable in individuals diagnosed with 4 personality disorders (schizotypal, borderline, avoidant, and obsessive-compulsive personality disorders) and examines the assumption that these personality disorders are stable by virtue of stable personality traits. This assumption was tested via the estimation of a series of latent longitudinal models that evaluated whether changes …