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2004

Theses and Dissertations

Alpha linolenic acid

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Treatment Of Hypertriglyceridemia With Omega-3 Fatty Acids: A Systematic Review, Amanda Gloria Lewis Jun 2004

Treatment Of Hypertriglyceridemia With Omega-3 Fatty Acids: A Systematic Review, Amanda Gloria Lewis

Theses and Dissertations

Purpose: To 1) critically appraise available randomized controlled trials (RTCs) addressing the efficacy of long-chain ω-3 fatty acids as a secondary prevention agent of hypertriglyceridemia, and 2) make recommendations for clinical practice.

Data Sources: All RCTs identified from several databases from 1993-2003 were reviewed by two independent reviewers who extracted data from each study and used the previously tested Boyack and Lookinland Methodological Quality Index (MQI) to determine study quality.

Results: Ten studies reported long-chain ω-3 fatty acids to be effective in the treatment of hypertriglyceridemia. The average decrease in triglycerides (TG) was 29%, total cholesterol (TC) 11.6%, very low …