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Interleukin-6 Levels In Generalized And Localized Aggressive Periodontitis Patients, Bindu Reddy Jan 2004

Interleukin-6 Levels In Generalized And Localized Aggressive Periodontitis Patients, Bindu Reddy

Theses and Dissertations

AbstractINTERLEUKIN-6 LEVELS IN GENERALIZED AND LOCALIZED AGGRESSIVE PERIODONTITIS PATIENTSBy Bindu Reddy, D.D.S.A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at the Virginia Commonwealth UniversityVirginia Commonwealth University, 2004Major Director: Joseph V. Califano, D.D.S., Ph.D.Associate Professor, Department of Periodontics Periodontitis is an inflammatory disease involving the supporting structures of the dentition. Many studies have shown that there is a relationship between periodontal disease, the presence of pro-inflammatory cytokines, and systemic disease such as cardiovascular disease and diabetes mellitus. The purpose of this study was to measure serum Interleukin-6 levels in generalized and localized aggressive …


The Association Between Periodontal Disease And C-Reactive Protein In Patients With A History Of Heart Attack, Robert Lee Fletcher Iii Jan 2004

The Association Between Periodontal Disease And C-Reactive Protein In Patients With A History Of Heart Attack, Robert Lee Fletcher Iii

Theses and Dissertations

The patient population consisted of a maximum of 18,570 subjects who completed the NHANES III questionnaire and examination from 1988 - 1994. The physical examination included such things as body mass index and serum samples, social and medical history. The periodontal examination recorded probing depth, attachment loss and gingival bleeding. Serum samples were analyzed for CRP levels, cholesterol levels etc. Demographic, cardiovascular and oral health variables were compared in subjects with a history of heart attack. Result showed that history of heart attack is associated with increased odds ratio for elevated CRP, diabetes, hypertension, cholesterol, male gender, non-white race and …


The Prevalence Of The Need For Esthetic Crown Lengthening In Post Orthodontically Treated Subjects, David Clark Johnson Jan 2004

The Prevalence Of The Need For Esthetic Crown Lengthening In Post Orthodontically Treated Subjects, David Clark Johnson

Theses and Dissertations

The problem of excess gingival display is difficult to diagnose and treat. By studying one aspect of excess gingival display, namely the size relationships of the clinical crowns of teeth, we can begin to quantify reasonable goals of therapy. In this study, two hundred plaster models were used as subjects. These represented two hundred patients before and after orthodontic therapy. The six anterior teeth were measured for length and width and compared to known ideals. Teeth that did not meet ideal standards may require treatment. It was found that the mean tooth length after orthodontic therapy was approximately two millimeters …


C-Reactive Protein Levels In Generalized Aggressive Periodontitis Patients, Trang Nguyen Salzberg Jan 2004

C-Reactive Protein Levels In Generalized Aggressive Periodontitis Patients, Trang Nguyen Salzberg

Theses and Dissertations

Background: There is mounting evidence to indicate that periodontitis may be a risk factor for cardiovascular disease (CVD). Periodontitis may be linked to CVD as either an etiologic mechanism or a predisposing factor that can hasten disease progression. Proinflammatory cytokines, elevated fibrinogen, and platelet aggregation are all potential mechanisms. The purpose of this study is to compare and review the serological differences in subjects with severe periodontitis, some of which involve established risk factors for atherosclerosis, particularly heightened C-reactive protein levels. Methods: A total of 184 subjects, comprising of two periodontal subgroups, non-periodontal (NP = 91) and generalized aggressive periodontitis …