Open Access. Powered by Scholars. Published by Universities.®
College of Nursing Faculty Research and Publications
Skeletal muscle wasting; cachexia; resistance exercise; electrical stimulation; colon-26 adenocarcinoma; animal models; mice
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Resistance Exercise Training Attenuates Wasting Of The Edl Muscle In Mice Bearing The Colon-26 Adenocarcinoma, Sadeeka Al-Majid, Donna O. Mccarthy
Resistance Exercise Training Attenuates Wasting Of The Edl Muscle In Mice Bearing The Colon-26 Adenocarcinoma, Sadeeka Al-Majid, Donna O. Mccarthy
College of Nursing Faculty Research and Publications
Progressive wasting of skeletal muscle is a significant side effect of malignancy. Perturbations in protein metabolism contribute to this state of wasting. Resistance exercise increases protein synthesis and mass of healthy muscles and counteracts muscle wasting associated with several catabolic conditions. It is not known whether resistance exercise training can counteract cancer-induced muscle wasting. This study examined the effect of resistance exercise training on muscle mass and protein content in 9 mice bearing the colon-26 adenocarcinoma. The dorsiflexor (extensor digitorum longus [EDL] and tibialis anterior) and plantar flexor (soleus, plantaris, and gastrocnemius) muscles of 1 leg of the tumor-bearing and …