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Chulalongkorn University Dental Journal
Clinico-pathological features; etiology; foam cells; verruciform xanthoma
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Verruciform Xanthoma(เวอรูซิฟอร์มแซนโทมา), Kittipong Dhanuthai
Verruciform Xanthoma(เวอรูซิฟอร์มแซนโทมา), Kittipong Dhanuthai
Chulalongkorn University Dental Journal
Verruciform xanthoma is a rare, benign entity which preferentially affects the oral mucosa than any other tissue. The most frequent site of involvement is the gingiva. It affects mostly the middleaged person with a predilection for male gender. Clinically, verruciform xanthoma appears as papillary or verrucous, flat or slightly raised lesions. Aggregates of lipid-laden foam cells confined to the connective tissue papillae between epithelial rete ridges in association with papillary or verrucous epithelial hyperplasia are the histolopathologic hallmark of this lesion. These foam cells are actually of macrophage/monocyte lineage. The histopathological distinction of verruciform xanthoma from other lesions, which it …