Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci
Decreasing Selenium Levels Andglutathione Peroxidase Activity In Patientswith Cutaneous Leishmaniasis, Abdurrahi̇m Koçyi̇ği̇t, Özcan Erel, Mehmet Sali̇h Gürel, Adnan Seyrek, Necmeddi̇n Aktepe, Selahatti̇n Gür, Senel Avci
Turkish Journal of Medical Sciences
For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p
The In Vitro Effects Of The Antimalarial Drug Primaquine, On The Activities Of Some Enzymes In Human Erythrocyte Lyzates, Meltem Müftüoğlu, Nazmi̇ Özer
The In Vitro Effects Of The Antimalarial Drug Primaquine, On The Activities Of Some Enzymes In Human Erythrocyte Lyzates, Meltem Müftüoğlu, Nazmi̇ Özer
Turkish Journal of Medical Sciences
The effect of primaquine on the enzymatic antioxidant defence mechanisms of erythrocytes were determined by measuring the activities of the below enzymes, before and after 30 minutes of incubation of hemolyzates with 1 mM primaquine at 37°C. Among the enzymes studied glucose-6- phosphate dehydrogenase seemed the most sensitive enzyme; 57 % and 78 % inhibition at zero (due to the binding of primaquine to NADP binding site) and 30 minutes of incubation (due to the reactive oxygen species), respectively. Catalase, superoxide dismutase, and glutathione-S-transferase were less sensitive to primaquine-derived reactive oxygen species: 33, 11, and 0 % inhibition at the …
Gsh-Px, G6pd And Arginase Activities And Some Biochemical Parameters In Cattle Infected With Theileria Annuluta, Sema Temi̇zer Ozan, Edi̇p Özer, Sema Yaralioğlu Gürgöze, Seval Yilmaz, Cem Ecmel Şaki̇, Murat Sevgi̇li̇
Gsh-Px, G6pd And Arginase Activities And Some Biochemical Parameters In Cattle Infected With Theileria Annuluta, Sema Temi̇zer Ozan, Edi̇p Özer, Sema Yaralioğlu Gürgöze, Seval Yilmaz, Cem Ecmel Şaki̇, Murat Sevgi̇li̇
Turkish Journal of Veterinary & Animal Sciences
Theileria annuluta, for which Hyalomma tick species serve as intermediate host, causes an economically important disease in cattle 15 cattle infected with T.annulata and 15 healthy cattle were used in the study. The activities of glutathione peroxidase (GSH-Px), glucose 6 phosphate dehydrogenase (G6PD) and arginase that play role in the free radical metabolism in erythrocytes, and serum aspartate transaminase (AST), alanine transaminase (ALT), total billirubin, cholesterol trigliserid, total protein, albumin, urea, uric acid, haemoglobin, haematocrit levels were measured. Erythrocyte GSH-Px and G6PD activities were measured by beutler, arginase activitiy by the modified TDMU method and other serum parameters were evaluated …