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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

1994

Theses/Dissertations

Life Sciences

William & Mary

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Full-Text Articles in Medicine and Health Sciences

In Vitro And In Vivo Effects Of Chemotherapeutants On The Oyster Parasite, Perkinsus Marinus, Gustavo W. Calvo Jan 1994

In Vitro And In Vivo Effects Of Chemotherapeutants On The Oyster Parasite, Perkinsus Marinus, Gustavo W. Calvo

Dissertations, Theses, and Masters Projects

To investigate the potential of chemotherapeutants to control the oyster pathogen Perkinsus marinus, anticoccidial and antifungal compounds were tested in vitro on infected hemolymph and cultured P. marinus cells and in vivo on infected oysters. In addition, acute toxicity to oysters was determined for six anticoccidials. In vitro experiments with infected hemolymph consisted of 24 h exposure of 0.2 mL hemolymph aliquots to concentrations ranging from 100 mg/L to 0.01 mg/L of amphotericin-B, amprolium, arprinocid, cycloheximide, lasalocid, malachite green, monensin, sulfadimethoxine, and a potentiated sulfadimethoxine, followed by incubation in fluid thioglycollate medium (FTM) to determine prezoosporangia abundance. Lasalocid, malachite green, …


Investigations Into Cataract Formation In Sciaenid Fish Species From The Elizabeth River, Chesapeake Bay, Virginia, Christopher D. Williams Jan 1994

Investigations Into Cataract Formation In Sciaenid Fish Species From The Elizabeth River, Chesapeake Bay, Virginia, Christopher D. Williams

Dissertations, Theses, and Masters Projects

Cataract formation in the Elizabeth River (ER) has been reported since 1986. Previous studies have concentrated on describing cataract as a function of exposure to polluted sediments, especially polycyclic aromatic hydrocarbons (PAH). These studies, however, have not examined what processes might be involved in fish cataractogenesis. The overall objective of this research was to identify important processes associated with the early development of cataract in feral fish populations. Field studies were used to systematically examine cataract development. Cataract in sciaenids was not associated with previously described cataractogenic factors, but could be linked to contaminated sediments of the ER. Cataract was …