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Full-Text Articles in Medicine and Health Sciences

Effect Of Propionic Acid-Derivative Ibuprofen On Neural Stem Call Differentiation; A Potential Link To Autism Spectrum Disorder, Aseelia Samsam Jan 2019

Effect Of Propionic Acid-Derivative Ibuprofen On Neural Stem Call Differentiation; A Potential Link To Autism Spectrum Disorder, Aseelia Samsam

Honors Undergraduate Theses

Propionic acid (PPA) is a short chain fatty acid that is produced by the human gut microbiome. Propionate, butyrate and acetates are the end products of the fermentation of the complex carbohydrates by human gut friendly microbiome and are being used as sources of energy in our body. PPA is used as a food preservative against molds in various daily products and has been implicated in the pathogenesis of autism. In a recent study we showed that PPA in human neuronal stem cell (NSC) culture increases the astrocyte population and decreases the neuronal number and increases the inflammatory cytokines. In …


Paraprofessional-Implemented Dialogic Reading And Its Impact On Children With Autism Spectrum Disorders, Annalise D. Irvine Jan 2018

Paraprofessional-Implemented Dialogic Reading And Its Impact On Children With Autism Spectrum Disorders, Annalise D. Irvine

Honors Undergraduate Theses

The purpose of this study was to evaluate the effectiveness of paraprofessional-implemented dialogic reading (DR) strategies on the comprehension, interaction, and attending abilities of a child on the autism spectrum. The secondary purpose was to understand whether the DR strategies assisted the paraprofessional in establishing meaningful interactions and positive behavioral changes with her student on the autism spectrum. A single subject across behaviors design was implemented with one paraprofessional and her student with autism. Judged from visual analysis of the graphical representation of the data, it was determined that there was a medium to strong functional relationship (depending on the …


Introversion And Autism: A Conceptual Exploration Of The Placement Of Introversion On The Autism Spectrum, Jennifer Grimes Jan 2010

Introversion And Autism: A Conceptual Exploration Of The Placement Of Introversion On The Autism Spectrum, Jennifer Grimes

Electronic Theses and Dissertations

The conceptualization of the personality construct of introversion has been problematic since the term's inception due to the complexity and seemingly self-contradictory nature of the collection of attributes of which it is comprised. To advance the understanding of introversion, I propose that it is a continuous segment of the non-clinical part of the autism spectrum, and that it is not the same as the inverse of extraversion. When introversion and autism are placed on the same continuum, the nature of the relationship of the traits becomes more apparent, and new possibilities are available for exploration of both autism and introversion. …


Categorical Perception Of Stop Consonants In Children With Autism, Laura Bourdeau Jan 2009

Categorical Perception Of Stop Consonants In Children With Autism, Laura Bourdeau

Electronic Theses and Dissertations

The purpose of this study is to determine whether children with autism recognize the same perceptual voicing boundaries of stop consonants as normally developing children of the same age group. This was explored using three groups of participants: ten children with autism between the ages of 8-14, five typically developing children between the ages of 8-14, and five typically developing seven-year-old children. Children in all groups listened to initial stop consonant syllables with voicing contrasts, with voiced and voiceless cognates presented. The initial consonants were altered along a voice onset time continuum within the typically perceived boundaries of each consonant. …