Medicine and Health Sciences Commons^™

The Walking Well: Effects Of Hypothalamic Amenorrhea On Athletic Performance, Annalise H. Lau

Doctor of Medical Science (DMSc)

Hormonal balance and normal menstrual cycles are key factors in athletic performance. Unfortunately, female athletes themselves are often under the impression that a lighter weight will improve their performance. Even many healthcare providers do not emphasize or are unaware of the health consequences of prolonged irregular menstruation. The main purpose of this article is to review the health consequences hypothalamic amenorrhea has on female athletes and to provide education for healthcare providers regarding the importance of recovery. A literature search was conducted utilizing PubMed, Scopus, PLOS One and EBSCO. The following keywords were input into the search bar: hypothalamic amenorrhea, …

Modeling Of Cns Cancer With A Focus On The Immune Component, Daniel Zamler

Dissertations & Theses (Open Access)

The knowledge surrounding cancers of the central nervous system remains poorly developed, in particular with regard to the immune component. The works contained in this thesis look at craniopharyngioma, glioblastoma, and several forms of brain metastasis. While some attention is given to the tumor cells themselves, as well as the patient setting which these studies model, the immune component of disease progression and treatment plays a strong role in each and is the primary focus of the works contained.

Craniopharyngioma is a relatively rare tumor in adults. Although histologically benign, it can be locally aggressive and may require additional therapeutic …

Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak

Honors Thesis

Influenza causes high numbers of illnesses and deaths annually (CDC, 2020). Influenza vaccines prevent these complications by reducing the risk of flu illness between 40-60% (CDC, 2021). However, no vaccination exists for infants under six months old so other methods, such as passive immunity, must be explored. To determine how infants can be protected, we tested the passive transfer of a universal influenza vaccine using a pig model and researched the mechanism of transfer. Four pregnant pigs were vaccinated one time with PBS and one time with HA-129 vaccine and four were vaccinated twice with the HA-129 vaccine. After farrowing, …

Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak

Honors Thesis

Influenza causes high numbers of illnesses and deaths annually (CDC, 2020). Influenza vaccines prevent these complications by reducing the risk of flu illness between 40-60% (CDC, 2021). However, no vaccination exists for infants under six months old so other methods, such as passive immunity, must be explored. To determine how infants can be protected, we tested the passive transfer of a universal influenza vaccine using a pig model and researched the mechanism of transfer. Four pregnant pigs were vaccinated one time with PBS and one time with HA-129 vaccine and four were vaccinated twice with the HA-129 vaccine. After farrowing, …