Medicine and Health Sciences Commons^™

Takotsubo Cardiomyopathy, Aimee Baker

Nursing Student Class Projects (Formerly MSN)

This poster evaluates the current understanding of Takotsubo Cardiomyopathy (TTC) and describes current treatment recommendations, long-term prognosis, and advanced practice nursing implications. TTC is a relatively rare disease and is present in about 2% of suspected ST-segment myocardial infarctions in women. (Sattar et al., 2017) TTC is not well understood and has several current hypotheses regarding cellular pathology. This poster explores the current understanding of pathophysiologicderangements from an organ system and two pathologic hypotheses at the cellular level. Current treatment recommendations include subclasses of treatments stratified by types of complications. Also, this poster introduces a new subclass of heart failure …

Assessment Of The Clinical Validity Of Ctdna Analysis For Melanoma Management, Anda-Gabriela Marsavela

Theses: Doctorates and Masters

Metastatic melanoma is responsible for almost 80% of all skin cancer-related deaths and the incidence of people affected continues to rise worldwide. The emergence of targeted therapy and immune-checkpoint inhibitors has improved the clinical management of melanoma, but durable survival benefit is only seen in a minority of patients. The use of these very expensive systemic therapies on all appropriate patients also poses a high economic burden on health systems across numerous countries. Currently, surveillance for treatment failure is not optimal. Thus, reliable and accurate biomarkers of patient disease status are urgently required.

Circulating tumour DNA (ctDNA) analysis has emerged …