Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Biochemical and Biomolecular Engineering (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Biology and Biomimetic Materials (1)
- Biomaterials (1)
-
- Biomedical (1)
- Biomedical Engineering and Bioengineering (1)
- Bioresource and Agricultural Engineering (1)
- Biotechnology (1)
- Business (1)
- Business Administration, Management, and Operations (1)
- Chemical Engineering (1)
- Computational Biology (1)
- Economics (1)
- Electrical and Computer Engineering (1)
- Engineering (1)
- Food Biotechnology (1)
- Food Microbiology (1)
- Food Processing (1)
- Food Science (1)
- Genetics and Genomics (1)
- Health Economics (1)
- Life Sciences (1)
- Materials Science and Engineering (1)
- Medical Biotechnology (1)
- Medical Molecular Biology (1)
- Medical Pharmacology (1)
- Molecular Biology (1)
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Hybridization Of Dna By Sequential Immobilization Of Oligonucleotides At The Air-Water Interface, Murali Sastry, Vidya Ramakrishnan, Mrunalini Pattarkine, Anand Gole, K. N. Ganesh
Hybridization Of Dna By Sequential Immobilization Of Oligonucleotides At The Air-Water Interface, Murali Sastry, Vidya Ramakrishnan, Mrunalini Pattarkine, Anand Gole, K. N. Ganesh
Faculty Works
The hybridization of DNA by sequential electrostatic and hydrogen-bonding immobilization of single-stranded complementary oligonucleotides at the air-water interface with cationic Langmuir monolayers is demonstrated. The complexation of the single-stranded DNA molecules with octadecylamine (ODA) Langmuir monolayers was followed in time by monitoring the pressure-area isotherms. A large (and slow) expansion of the ODA monolayer was observed during each stage of complexation in the following sequence: primary single-stranded DNA followed by complementary single-stranded DNA followed by the intercalator, ethidium bromide. Langmuir-Blodgett (LB) films of the ODA-DNA complex were formed on different substrates and characterized using quartz-crystal microgravimetry (QCM), Fourier transform infrared …
Position Of Γ-Chain Carboxy-Terminal Regions In Fibrinogen/Fibrin Cross-Linking Mixtures, Kevin R. Siebenlist, David A. Meh, Michael W. Mosesson
Position Of Γ-Chain Carboxy-Terminal Regions In Fibrinogen/Fibrin Cross-Linking Mixtures, Kevin R. Siebenlist, David A. Meh, Michael W. Mosesson
Biomedical Sciences Faculty Research and Publications
There are conflicting ideas regarding the location of the carboxyl-terminal regions of cross-linked γ-chain dimers in double-stranded fibrin fibrils. Some investigators believe that the chains are always oriented longitudinally along each fibril strand and traverse the contacting ends of abutting fibrin D domains (“DD-long” cross-linking). Other investigations have indicated instead that the chains are situated transversely between adjacent D domains in opposing fibril strands (transverse cross-linking). To distinguish between these two possibilities, the γ dimer composition of factor XIIIa-cross-linked fibrin/fibrinogen complexes that had been formed through noncovalent D/E interactions between fibrinogen D domains and fibrin E domains was examined. Two …