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Full-Text Articles in Medicine and Health Sciences

Introduction Of Behavioural Based Safety, Ian Price Jan 2003

Introduction Of Behavioural Based Safety, Ian Price

Faculty of Science, Medicine and Health - Papers: part A

Behavioural Based Safety in the workplace is the application of industrial or organisational psychology to promote health and safety (I). Our own complexities makes us all fallible, whether it be from the fact we love to push the boundaries, challenge authority, cognitive failures, memory lapse, processing errors or personal health related problems, we make mistakes (2). Generally thought as a species we do try to do the right thing, co-operate with one another, and don't go out of our way to be disobedient or want to cause physical harm or damage. Behavioural Based Safety can be said to be a …


Aqua(Pyridine-Kn)(N-Salicylidenetyrosinaot-K3 O,N,O')Copper (Ii), Ray J. Butcher, Garry Mockler, Owen Mckern Jan 2003

Aqua(Pyridine-Kn)(N-Salicylidenetyrosinaot-K3 O,N,O')Copper (Ii), Ray J. Butcher, Garry Mockler, Owen Mckern

Faculty of Science, Medicine and Health - Papers: part A

The tridentate Schiff base ligand derived from the conden­s­ation of salicyl­aldehyde and dl-tyrosine, in the presence of pyridine, forms a square-pyramidal five-coordinate Cu complex, [Cu(C16H13NO4)(C5H5N)(H2O)], with a water mol­ecule occupying the apical site.


(Piperidine-Kn)[N-(Salicylidene)Phenylalaninato-K3 0,N,0']Copper(Ii), Ray J. Butcher, Garry Mockler, Owen Mckern Jan 2003

(Piperidine-Kn)[N-(Salicylidene)Phenylalaninato-K3 0,N,0']Copper(Ii), Ray J. Butcher, Garry Mockler, Owen Mckern

Faculty of Science, Medicine and Health - Papers: part A

The tridentate Schiff base ligand derived from the condens­ation of salicyl­aldehyde and l-phenyl­alanine, in the presence of piperidine, when reacted with copper sulfate pentahydrate, forms a polymeric square pyramidal five-coord­inate copper complex, [Cu(C17H14O3)(C4H10N2)]. The axial position of the square pyramid is occupied by the carboxyl O atoms of a neighboring mol­ecule.


Catena-Poly[[(Pyridine-Kn)Copper(Ii)]U-N-Salicylideneglycinato-K40,N,0':0'], Ray J. Butcher, Garry Mockler, Owen Mckern Jan 2003

Catena-Poly[[(Pyridine-Kn)Copper(Ii)]U-N-Salicylideneglycinato-K40,N,0':0'], Ray J. Butcher, Garry Mockler, Owen Mckern

Faculty of Science, Medicine and Health - Papers: part A

The tridentate Schiff base ligand derived from the condensation of salicyl­aldehyde and glycine, in the presence of pyridine, forms the title polymeric square-pyramidal five-coordinate copper complex, [Cu(C5H5N)(C9H7NO3)(C5H5N)], in which the copper centers are linked via the carboxyl O atoms of neighboring groups occupying the apical site.


An Archaeology Of Historical Reality?: A Case Study Of The Recent Past, Alistair Paterson, Nicholas Gill, M.J. Kennedy Jan 2003

An Archaeology Of Historical Reality?: A Case Study Of The Recent Past, Alistair Paterson, Nicholas Gill, M.J. Kennedy

Faculty of Science, Medicine and Health - Papers: part A

An Aboriginal elder, an archaeologist and a geographer report on an interdisciplinary project about colonial-era settlement in the Murchison and Davenport ranges in the Northern Territory. Oral history, physical evidence and historical records reveal a distinct central Australian cultural landscape and show that archaeology can do more than merely exhume material to support historical 'realities'. This project provides new or improved understandings of (1) colonial technology in pastoral ventures, (2) continuity and change in Aboriginal life following European arrival, (3) social behaviour in colonial settings, and (4) alternatives to Eurocentric Australian histories.


Poisoned Patients As Potential Organ Donors: Postal Survey Of Transplant Centres And Intensive Care Units, David Michael Wood, Paul Ivor Dargan, Alison L. Jones Jan 2003

Poisoned Patients As Potential Organ Donors: Postal Survey Of Transplant Centres And Intensive Care Units, David Michael Wood, Paul Ivor Dargan, Alison L. Jones

Faculty of Science, Medicine and Health - Papers: part A

Background The number of patients awaiting allograft transplantation in the UK exceeds the number of organs offered for transplantation each year. Most organ donors tend to be young, fit and healthy individuals who die because of trauma or sudden cardiac arrest. Patients who die from drug and poison intoxication tend to have similar characteristics but are less frequently offered as potential organ donors. Methods A postal questionnaire survey of all transplantation centres and an equal number of intensive care units in the UK was undertaken. The use of kidney, heart, lung, liver and pancreas transplants from poisoned patients following deliberate …


Disturbance-Mediated Competition And The Spread Of Phragmites Australis In A Coastal Marsh, Todd Minchinton, Mark D. Bertness Jan 2003

Disturbance-Mediated Competition And The Spread Of Phragmites Australis In A Coastal Marsh, Todd Minchinton, Mark D. Bertness

Faculty of Science, Medicine and Health - Papers: part A

In recent decades the grass Phragmites australis has been aggressively invading coastal, tidal marshes of North America, and in many areas it is now considered a nuisance species. While P. australis has historically been restricted to the relatively benign upper border of brackish and salt marshes, it has been expanding seaward into more physiologically stressful regions. Here we test a leading hypothesis that the spread of P. australis is due to anthropogenic modification of coastal marshes. We did a field experiment along natural borders between stands of P. australis and the other dominant grasses and rushes (i.e., matrix vegetation) in …


Mid-Late Holocene El Nino Variability In The Equatorial Pacific From Coral Microatolls, Colin Woodroffe, Matthew R. Beech, Michael K. Gagan Jan 2003

Mid-Late Holocene El Nino Variability In The Equatorial Pacific From Coral Microatolls, Colin Woodroffe, Matthew R. Beech, Michael K. Gagan

Faculty of Science, Medicine and Health - Papers: part A

Oxygen isotope ratios in Porites microatolls from Christmas Island in the central Pacific provide high-resolution proxy records of El Niño-Southern Oscillation (ENSO) variability since 3.8 thousand years ago (ka). Compared with modern microatolls, reconstructions from fossil microatolls imply that interannual variations in ENSO sea-surface temperature and precipitation were less intense 3.8–2.8 ka, but more pronounced at 1.7 ka. Amplification of ENSO at ∼2 ka is consistent with precessional changes in insolation seasonality, but exceeds model predictions and may reflect stronger rainfall teleconnections through enhanced interaction between the Southern Oscillation and the Pacific Intertropical Convergence Zone.


Food And Nutritional Supplements. Their Role In Health And Disease, Anne-Therese Mcmahon Jan 2003

Food And Nutritional Supplements. Their Role In Health And Disease, Anne-Therese Mcmahon

Faculty of Science, Medicine and Health - Papers: part A

Book review of: Food and nutritional supplements. Their role in health and disease J K Ransley, J K Donnelly and NW Read (eds) Springer-Verlag Berlin, 2001. ISBN 3-540-41737-0 197pp c. A$120


Cell Surface Antigens Of Mycoplasma Species Bovine Group 7 Bind And Activate Plasminogen, Kylie Bower, Steven Djordjevic, Nicholas M Andronicos, Marie Ranson Jan 2003

Cell Surface Antigens Of Mycoplasma Species Bovine Group 7 Bind And Activate Plasminogen, Kylie Bower, Steven Djordjevic, Nicholas M Andronicos, Marie Ranson

Faculty of Science, Medicine and Health - Papers: part A

Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins.


Work-Based Physiological Assessment Of Physically-Demanding Trades: A Methodological Overview, Nigel A.S. Taylor, Herbert Groeller Jan 2003

Work-Based Physiological Assessment Of Physically-Demanding Trades: A Methodological Overview, Nigel A.S. Taylor, Herbert Groeller

Faculty of Science, Medicine and Health - Papers: part A

Technological advances, modified work practices, altered employment strategies, work-related injuries, and the rise in work-related litigation and compensation claims necessitate ongoing trade analysis research. Such research enables the identification and development of gender- and age-neutral skills, physiological attributes and employment standards required to satisfactorily perform critical trade tasks. This paper overviews a methodological approach which may be adopted when seeking to establish trade-specific physiological competencies for physically-demanding trades (occupations). A general template is presented for conducting a trade analyses within physically-demanding trades, such as those encountered within military or emergency service occupations. Two streams of analysis are recommended: the trade …


Bovine Non-O157 Shiga Toxin 2-Containing Escherichia Coli Isolates Commonly Possess Stx2-Edl933 And/Or Stx2vhb Subtypes, Kim Brett, Michael A Hornitzky, Karl A Bettelheim, Mark J. Walker, Steven Djordjevic Jan 2003

Bovine Non-O157 Shiga Toxin 2-Containing Escherichia Coli Isolates Commonly Possess Stx2-Edl933 And/Or Stx2vhb Subtypes, Kim Brett, Michael A Hornitzky, Karl A Bettelheim, Mark J. Walker, Steven Djordjevic

Faculty of Science, Medicine and Health - Papers: part A

stx2 genes from 138 Shiga toxin-producing Escherichia coli (STEC) isolates, of which 127 were of bovine origin (58 serotypes) and 11 of human origin (one serotype; O113:H21), were subtyped. The bovine STEC isolates from Australian cattle carried ehxA and/or eaeA and predominantly possessed stx2-EDL933 (103 of 127; 81.1%) either in combination with stx2vhb (32 of 127; 25.2%) or on its own (52 of 127; 40.4%). Of 22 (90.9%) bovine isolates of serotype O113:H21, a serotype increasingly recovered from patients with hemolytic uremic syndrome (HUS) or hemorrhagic colitis, 20 contained both stx2-EDL933 and stx2vhb; 2 …


Towards A Sounder Fire Ecology, Edward A. Johnson, A Malcolm Gill, Ross Bradstock, Anders Granstrom, Louis Trabaud, Kiyoko Miyanishi Jan 2003

Towards A Sounder Fire Ecology, Edward A. Johnson, A Malcolm Gill, Ross Bradstock, Anders Granstrom, Louis Trabaud, Kiyoko Miyanishi

Faculty of Science, Medicine and Health - Papers: part A

This forum brings together fire ecologists from outside the current wildfire controversy in the US to give their views on three central topics related to ecosystems in which wildfires are an important process. First, how do fire behavior and ecological effects vary between ecosystems? Second, why does this variation require an understanding that goes beyond simple correlations between various fire and ecosystem variables to more careful causal models? Third, how can human values and goals be reconciled with fire disturbance processes in an ecologically sound manner?


Intercomparison Of Ndsc Ground-Based Solar Ftir Measurements Of Atmospheric Gases At Lauder, New Zealand, D W. T Griffith, Nicholas Jones, B Mcnamara, Clare Paton-Walsh, W. R. Bell, Cirilo Bernado Jan 2003

Intercomparison Of Ndsc Ground-Based Solar Ftir Measurements Of Atmospheric Gases At Lauder, New Zealand, D W. T Griffith, Nicholas Jones, B Mcnamara, Clare Paton-Walsh, W. R. Bell, Cirilo Bernado

Faculty of Science, Medicine and Health - Papers: part A

A formal intercomparison of atmospheric total column measurements of N2O, N2, CH4, O3, HCl, HNO3, and HF by two ground-based solar Fourier transform infrared (FTIR) spectrometers conducted as part of the Network for the Detection of Stratospheric Change (NDSC) instrument certification procedure at Lauder, New Zealand, is presented. The two instruments were nominally very similar, collocated, and collected data at the same times. Collected spectra were analyzed independently by the individual operators in a blind-phase intercomparison, then reanalyzed by a single operator using identical analysis methods to eliminate any potential …


Stx1c Is The Most Common Shiga Toxin 1 Subtype Among Shiga Toxin-Producing Escherichia Coli Isolates From Sheep But Not Among Isolates From Cattle, Kim Brett, Vidiya Ramachandran, Michael A Hornitzky, Karl A Bettelheim, Mark J. Walker, Steven P. Djordjevic Jan 2003

Stx1c Is The Most Common Shiga Toxin 1 Subtype Among Shiga Toxin-Producing Escherichia Coli Isolates From Sheep But Not Among Isolates From Cattle, Kim Brett, Vidiya Ramachandran, Michael A Hornitzky, Karl A Bettelheim, Mark J. Walker, Steven P. Djordjevic

Faculty of Science, Medicine and Health - Papers: part A

Unlike Shiga toxin 2 (stx2) genes, most nucleotide sequences of Shiga toxin 1 (stx1) genes from Shiga toxin-producing Escherichia coli (STEC), Shigella dysenteriae, and several bacteriophages (H19B, 933J, and H30) are highly conserved. Consequently, there has been little incentive to investigate variants of stx1 among STEC isolates derived from human or animal sources. However stx1OX3, originally identified in an OX3:H8 isolate from a healthy sheep in Germany, differs from other stx1 subtypes by 43 nucleotides, resulting in changes to 12 amino acid residues, and has been renamed stx1c …


Dehydration And Partial Melting In Subduction Zones: Constraints From U-Series Disequilibria, Bernard Bourdon, Simon Turner, Anthony Dosseto Jan 2003

Dehydration And Partial Melting In Subduction Zones: Constraints From U-Series Disequilibria, Bernard Bourdon, Simon Turner, Anthony Dosseto

Faculty of Science, Medicine and Health - Papers: part A

We present a critical reappraisal of U-series data from arc volcanoes to constrain slab dehydration and melting processes using a global subduction zone data set. There is no clear evidence for significant mobilization of Th or Pa in dehydration fluids while the source region of arc rocks is relatively oxidized and mobility of U is strongly enhanced. It is argued that along-arc U/Th and U/Pa isotope data reflect time-integrated addition of U from the slab to the mantle wedge. The presence of large Ra-Th disequilibrium correlated with Ba/Th ratios provides evidence for some very recent fluid addition and fast magma …


Long-Term Trends Of Inorganic Chlorine From Ground-Based Infrared Solar Spectra: Past Increases And Evidence For Stabilization, C P. Rinsland, E Mahieu, R Zander, Nicholas Jones, M P. Chipperfield, A Goldman, J Anderson, J M. Russell Iii, P Demoulin, J Notholt, G C. Toon, Jean-Francois Blavier, B Sen, R Sussmann, S W. Wood, A Meier, D W. T Griffith, L Chiou, F Murcray, T M. Stephen, Frank Hase, S Mikuteit, A Schultz, T Blumenstock Jan 2003

Long-Term Trends Of Inorganic Chlorine From Ground-Based Infrared Solar Spectra: Past Increases And Evidence For Stabilization, C P. Rinsland, E Mahieu, R Zander, Nicholas Jones, M P. Chipperfield, A Goldman, J Anderson, J M. Russell Iii, P Demoulin, J Notholt, G C. Toon, Jean-Francois Blavier, B Sen, R Sussmann, S W. Wood, A Meier, D W. T Griffith, L Chiou, F Murcray, T M. Stephen, Frank Hase, S Mikuteit, A Schultz, T Blumenstock

Faculty of Science, Medicine and Health - Papers: part A

Long-term time series of hydrogen chloride (HCl) and chlorine nitrate (ClONO2) total column abundances has been retrieved from high spectral resolution ground-based solar absorption spectra recorded with infrared Fourier transform spectrometers at nine NDSC (Network for the Detection of Stratospheric Change) sites in both Northern and Southern Hemispheres. The data sets span up to 24 years and most extend until the end of 2001. The time series of Cly (defined here as the sum of the HCl and ClONO2 columns) from the three locations with the longest time-span records show rapid increases until the early 1990s …


The Nature And Prevalence Of Psychological Problems In New Zealand Primary Healthcare: A Report On Mental Health And General Practice Investigation ( Magpie), John Bushnell, Deborah Mcleod, A D. Dowell, C Salmond, S Ramage, S Collings, P Ellis, Marjan Kljakovic, L Mcbain Jan 2003

The Nature And Prevalence Of Psychological Problems In New Zealand Primary Healthcare: A Report On Mental Health And General Practice Investigation ( Magpie), John Bushnell, Deborah Mcleod, A D. Dowell, C Salmond, S Ramage, S Collings, P Ellis, Marjan Kljakovic, L Mcbain

Faculty of Science, Medicine and Health - Papers: part A

Aims This paper describes the methods used in a study of the prevalence and types of common mental disorders among patients attending New Zealand general practices, and reports some key findings from the first phase of the study. The study also aimed to determine the degree of associated disability and other factors influencing recognition, management, course and outcome of these disorders, and subsequent papers will address these issues. Methods General practitioners (GPs) were selected randomly. In the first phase of the study, all adult attenders at each practice on selected days were administered a short questionnaire, the General Health Questionnaire …


Better Ways To Cook Bacon - Reflecting On Nursing, Kenneth Walsh Jan 2003

Better Ways To Cook Bacon - Reflecting On Nursing, Kenneth Walsh

Faculty of Science, Medicine and Health - Papers: part A

Editorial


Who's Driving The Asylum Debate: Newspaper And Government Representations Of Asylum Seekers, Natascha Klocker, Kevin M. Dunn Jan 2003

Who's Driving The Asylum Debate: Newspaper And Government Representations Of Asylum Seekers, Natascha Klocker, Kevin M. Dunn

Faculty of Science, Medicine and Health - Papers: part A

The welfare and future of asylum seekers in Australia have been very contentious contemporary issues. Findings based on content analysis of media releases in 2001 and 2002 reveal the unrelentingly negative way in which the federal government portrayed asylum seekers. While the government's negative tenor was constant during the study period, the specific terms of reference altered, from 'threat' through 'other', to 'illegality' and to 'burden'. The negative construction of asylum seekers was clearly mutable. Analysis of newspaper reporting during the same period indicates that the media largely adopted the negativity and specific references of the government. The media dependence …


Flexibility Revealed By The 1.85 Å Crystal Structure Of The Β Sliding-Clamp Subunit Of Escherichia Coli Dna Polymerase Iii, Aaron J. Oakley, Pavel Prosselkov, Gene Wijffels, Jennifer L. Beck, Matthew Cj Wilce, Nicholas E. Dixon Jan 2003

Flexibility Revealed By The 1.85 Å Crystal Structure Of The Β Sliding-Clamp Subunit Of Escherichia Coli Dna Polymerase Iii, Aaron J. Oakley, Pavel Prosselkov, Gene Wijffels, Jennifer L. Beck, Matthew Cj Wilce, Nicholas E. Dixon

Faculty of Science, Medicine and Health - Papers: part A

The subunit of the Escherichia coli replicative DNA polymerase III holoenzyme is the sliding clamp that interacts with the (polymerase) subunit to maintain the high processivity of the enzyme. The protein is a ring-shaped dimer of 40.6 kDa subunits whose structure has previously been determined at a resolution of 2.5 Å [Kong et al. (1992), Cell, 69, 425-437]. Here, the construction of a new plasmid that directs overproduction of to very high levels and a simple procedure for large-scale purification of the protein are described. Crystals grown under slightly modified conditions diffracted to beyond 1.9 Å at 100 …


Geochronology Of Coal Measures In The Sydney Basing From U-Pb Shrimp Dating Of Airfall Tuffs, Paul F. Carr, M Fanning, Brian G. Jones, Adrian C. Hutton Jan 2003

Geochronology Of Coal Measures In The Sydney Basing From U-Pb Shrimp Dating Of Airfall Tuffs, Paul F. Carr, M Fanning, Brian G. Jones, Adrian C. Hutton

Faculty of Science, Medicine and Health - Papers: part A

Zircon-bearing rhyolitic and dacitic airfall tuffs in the Late Permian Sydney Basin coal measures provide ideal chronostratigraphic markers due to their widespread occurrence and rapid emplacement. SHRIMP U-Pb zircon dates for several stratigraphically-controlled airfall tuffs are consistent with their relative ages and biostratigraphic data, and indicate that the Illawarra Coal Measures accumulated in less than ~ 12 million years. Isotopic ages of the A waba Tuff and the Burragorang Claystone Member are indistinguishable within analytical uncertainty and support the correlation of these units proposed previously on the basis of geochemical fingerprinti~g. Deposition of coal-bearing sequences in the southern Sydney Basin …


Anthropogenic Trace Metal Contamination Of Port Kembla Harbour Sediments, Bryan E. Chenhall, Mark O'Donnell, D Garnett, Helen Waldron, Brian G. Jones Jan 2003

Anthropogenic Trace Metal Contamination Of Port Kembla Harbour Sediments, Bryan E. Chenhall, Mark O'Donnell, D Garnett, Helen Waldron, Brian G. Jones

Faculty of Science, Medicine and Health - Papers: part A

Detailed geochemical investigation of the bottom sediments in Port Kembla Harbour using neutron activation (NAA) and X-ray-fluorescence (XRF) techniques has delineated areas severely impacted by anthropogenically-sourced trace elements including potentially toxic metals (Pb, Cu) and metalloids (As and Se). In the south western section of Port Kembla Outer Harbour, copper concentrations in excess of 6000 ppm (~30x ANZECC-ARMCANZ (2000) ISQG-high trigger value) are associated with significant (i.e. above ISQH-high) concentrations oflead, zinc and arsenic. The potential source of sediment contamination here is the Port Kembla Copper (formerly ERS and Southern Copper) smelter. Port Kembla Inner Harbour sediments are geochemically distinct …


Resource Significance Of Overwash Sand Deposits From The Southern Sydney Basin, Adam D. Switzer, Kevin Pucillo, Brian G. Jones, Edward A. Bryant Jan 2003

Resource Significance Of Overwash Sand Deposits From The Southern Sydney Basin, Adam D. Switzer, Kevin Pucillo, Brian G. Jones, Edward A. Bryant

Faculty of Science, Medicine and Health - Papers: part A

Sand extraction from coastal sand dunes results in significant loss of sand from the natural system, destruction of dune vegetation and dramatic geo-technical modification. This can place significant limitations on land use. The identification of, and extraction from sand bodies that are not part of active coastal barriers or dune structures is therefore considered to be a more environmentally sound practice . Sedimentological investigation of several back-barrier estuarine sequences have located several marine sand deposits within the Illawarra region that meet the above criteria. The action of overwash, possibly by tsunami waves in the late Holocene has deposited large volumes …


The Chronostratigraphy Of A Holocene Barrier Estuary: Lake Illawarra Nsw, Craig R. Sloss, Brian G. Jones, Colin V. Murray-Wallace, Charles Mcclennan Jan 2003

The Chronostratigraphy Of A Holocene Barrier Estuary: Lake Illawarra Nsw, Craig R. Sloss, Brian G. Jones, Colin V. Murray-Wallace, Charles Mcclennan

Faculty of Science, Medicine and Health - Papers: part A

Valley-fill sequences, preserved in topographic lows associated with incised valley systems, potentially preserve a record of Holocene sea level fluctuations. A detailed litho- and biostratigraphy of the Holocene barrier estuary, Lake Illawarra, New South Wales has been constructed. Forty kilometres of seismic surveys, forty-one vibracores, supplemented by auger drill holes and trenches, and faunal analysis provides the data for this investigation. A detailed chronology of the infilling of the barrier estuary has been established using 115 aspartic acid derived ages and six radiocarbon ages. The results provide a detailed chronology for the deposition of marine transgressive deposits, barrier growth, and …


Revised Age For Mojokerto 1, An Early Homo Erectus Cranium From East Java, Indonesia, Michael Morwood, P O'Sullivan, E E. Susanto, F Aziz Jan 2003

Revised Age For Mojokerto 1, An Early Homo Erectus Cranium From East Java, Indonesia, Michael Morwood, P O'Sullivan, E E. Susanto, F Aziz

Faculty of Science, Medicine and Health - Papers: part A

Dates of around 1.8 Ma have been claimed for a hominin cranial vault excavated near Mojokerto City in East Java, Indonesia. Such an early date for presumed Homo erectus in East Asia would require a major revision of the general model for timing of initial hominin dispersal 'Out of Africa'. Instead, our field study and redating of two pumice horizons at the site indicate that the age of the Mojokerto cranial vault is less than 1.49 Ma. Furthermore, we argue that a basic understanding of site and regional depositional processes is fundamental for assessing the significance of any radiometric date.


Distribution Of Intimin Subtypes Among Escherichia Coli Isolates From Ruminant And Human Sources, Vidiya Ramachandran, Kim Brett, Michael A Hornitzky, Mark Dowton, Karl A Bettelheim, Mark J. Walker, Steven P. Djordjevic Jan 2003

Distribution Of Intimin Subtypes Among Escherichia Coli Isolates From Ruminant And Human Sources, Vidiya Ramachandran, Kim Brett, Michael A Hornitzky, Mark Dowton, Karl A Bettelheim, Mark J. Walker, Steven P. Djordjevic

Faculty of Science, Medicine and Health - Papers: part A

The intimin gene eae, located within the locus of enterocyte effacement pathogenicity island, distinguishes enteropathogenic Escherichia coli (EPEC) and some Shiga toxin-producing E. coli (STEC) strains from all other pathotypes of diarrheagenic E. coli. EPEC is a leading cause of infantile diarrhea in developing countries, and intimin-positive STEC isolates are typically associated with life-threatening diseases such as hemolytic-uremic syndrome and hemorrhagic colitis. Here we describe the development of a PCR-restriction fragment length polymorphism (RFLP) assay that reliably differentiates all 11 known intimin types (α1, α2, β, γ, κ, ɛ, η, ι, λ, θ, and ζ) and three new …


Evolution Of Sfbi Encoding Streptococcal Fibronectin-Binding Protein I: Horizontal Genetic Transfer And Gene Mosaic Structure, Rebecca J. Towers, Peter K. Fagan, Susanne R. Talay, Bart J. Currie, Kadaba S. Sriprakash, Mark J. Walker, Gursharan S. Chhatwal Jan 2003

Evolution Of Sfbi Encoding Streptococcal Fibronectin-Binding Protein I: Horizontal Genetic Transfer And Gene Mosaic Structure, Rebecca J. Towers, Peter K. Fagan, Susanne R. Talay, Bart J. Currie, Kadaba S. Sriprakash, Mark J. Walker, Gursharan S. Chhatwal

Faculty of Science, Medicine and Health - Papers: part A

Streptococcal fibronectin-binding protein is an important virulence factor involved in colonization and invasion of epithelial cells and tissues by Streptococcus pyogenes. In order to investigate the mechanisms involved in the evolution of sfbI, the sfbI genes from 54 strains were sequenced. Thirty-four distinct alleles were identified. Three principal mechanisms appear to have been involved in the evolution of sfbI. The amino-terminal aromatic amino acid-rich domain is the most variable region and is apparently generated by intergenic recombination of horizontally acquired DNA cassettes, resulting in a genetic mosaic in this region. Two distinct and divergent sequence types that …


The Challenge Of Intimacy: Fathers Experiences, Moira Williamson, Mercy Baafi, Carol Mcveigh Jan 2003

The Challenge Of Intimacy: Fathers Experiences, Moira Williamson, Mercy Baafi, Carol Mcveigh

Faculty of Science, Medicine and Health - Papers: part A

From an exploratory study that looked at the functional status of fathers following birth, the authors have gained insight into the effect of pregnancy, birth and the postnatal period on the sexual relationships of couples. A qualitative approach was undertaken of fathers written comments in a survey conducted at 6, 12 and 24 weeks postpartum. A total of 204 fathers were enrolled in the study with a response rate of 63% for the first survey. A content analysis of the first survey was conducted on the comments made about sexuality in pregnancy and the early postpartum period. From result of …


The Reduced Effect Of Serotonin On Oxygen Consumption During Muscle Contraction In The Autoperfused Rat Hindlimb, Andrew Hoy, Gregory E. Peoples, Peter L. Mclennan Jan 2003

The Reduced Effect Of Serotonin On Oxygen Consumption During Muscle Contraction In The Autoperfused Rat Hindlimb, Andrew Hoy, Gregory E. Peoples, Peter L. Mclennan

Faculty of Science, Medicine and Health - Papers: part A

Serotonin (5-HT) has been shown to reduce skeletal muscle oxygen consumption cY 02) during resting conditions in a variety of animal models. It is thought to act through redistribution of blood flow within skeletal muscle directing flow away from muscle tissue (nutritive bed) towards less metabolically active tissue, adipose and septum (non-nutritive bed) by selective vasoconstriction. The aim of this study was to test whether the effects of 5-HT (previously observed under resting conditions) are reproducible during the increased metabolic demand of muscle contraction.