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Full-Text Articles in Medicine and Health Sciences

Body Mass Index And Diabetes Mellitus May Predict Poorer Overall Survival Of Oral Squamous Cell Carcinoma Patients: A Retrospective Cohort From A Tertiary-Care Center Of A Resource-Limited Country, Yumna Adnan, Syed Muhammad Adnan Ali, Mohammad Sohail Awan, Nida Zahid, Muhammad Ozair Awan, Hammad Afzal Kayani, Hasnain Ahmed Farooqui Mar 2022

Body Mass Index And Diabetes Mellitus May Predict Poorer Overall Survival Of Oral Squamous Cell Carcinoma Patients: A Retrospective Cohort From A Tertiary-Care Center Of A Resource-Limited Country, Yumna Adnan, Syed Muhammad Adnan Ali, Mohammad Sohail Awan, Nida Zahid, Muhammad Ozair Awan, Hammad Afzal Kayani, Hasnain Ahmed Farooqui

Department of Surgery

Introduction: Oral squamous cell carcinoma (OSCC) is one of the highest-ranking cancers among both genders in Pakistan. Obesity is linked to a much higher risk for developing multiple cancer types. Individuals with Diabetes mellitus (DM) face an increased risk for developing oral cancer. Hence, the objective of this study was to identify the effect of obesity and DM on the prognosis of OSCC patients.
Methods: This retrospective cohort analysis was conducted on 386 patients diagnosed and treated for OSCC at The Aga Khan University Hospital, Karachi, Pakistan. Patient information was obtained from hospital medical records. Obesity was defined as having …


Understanding Deep Learning - Challenges And Prospects, Niha Adnan, Fahad Umer Feb 2022

Understanding Deep Learning - Challenges And Prospects, Niha Adnan, Fahad Umer

Department of Surgery

The developments in Artificial Intelligence have been on the rise since its advent. The advancements in this field have been the innovative research area across a wide range of industries, making its incorporation in dentistry inevitable. Artificial Intelligence techniques are making serious progress in the diagnostic and treatment planning aspects of dental clinical practice. This will ultimately help in the elimination of subjectivity and human error that are often part of radiographic interpretations, and will improve the overall efficiency of the process. The various types of Artificial Intelligence algorithms that exist today make the understanding of their application quite complex. …


Comparison Of Fracture And Deformation In The Rotary Endodontic Instruments: Protaper Versus K-3 System, Sana Ehsen Nagi, Farhan Raza Khan, Munawar Rahman Oct 2016

Comparison Of Fracture And Deformation In The Rotary Endodontic Instruments: Protaper Versus K-3 System, Sana Ehsen Nagi, Farhan Raza Khan, Munawar Rahman

Department of Surgery

Abstract

This experimental study was done on extracted human teeth to compare the fracture and deformation of the two rotary endodontic files system namely K-3 and Protapers. It was conducted at the dental clinics of the Aga Khan University Hospital, Karachi, A log of file deformation or fracture during root canal preparation was kept. The location of fracture was noted along with the identity of the canal in which fracture took place. The fracture in the two rotary systems was compared. SPSS 20 was used for data analysis. Of the 172(80.4%) teeth possessing more than 15 degrees of curvature, fracture …


Prevalence Of Musculoskeletal Disorders Among Dentists In Teaching Hospitals In Karachi, Muhammad Hasan Hameed, Rabia Ghafoor, Farhan Raza Khan, Sheikh Bilal Badar Oct 2016

Prevalence Of Musculoskeletal Disorders Among Dentists In Teaching Hospitals In Karachi, Muhammad Hasan Hameed, Rabia Ghafoor, Farhan Raza Khan, Sheikh Bilal Badar

Department of Surgery

Work-related musculoskeletal pain is common among healthcare professionals, including dentists. This crosssectional study was conducted to determine the prevalence of work-related musculoskeletal disorders (MSDs) among dentists. This study was carried out from January to April 2016 at various teaching hospitals of Karachi, and comprised 230 dentists. A self-administered questionnaire, adapted from a validated Nordic questionnaire, was distributed among the participants. Descriptive statistics were computed and associations of interest were analysed using chi-square test. Of the 230 forms, 182(79.11%) were included after leaving out the incomplete ones. The overall prevalence of MSDs was 138(75.8%). The most frequent reasonsfor MSDs were lack …


A 6-Year Evaluation Of 223 Tapered Dental Implants And Associated Prosthesis In 92 Patients At A University Hospital, Sana Ehsen Nagi, Farhan Raza Khan, Khan, Rabia Ali Oct 2016

A 6-Year Evaluation Of 223 Tapered Dental Implants And Associated Prosthesis In 92 Patients At A University Hospital, Sana Ehsen Nagi, Farhan Raza Khan, Khan, Rabia Ali

Department of Surgery

Abstract

The aim of the retrospective study was to assess the clinical and radiographic outcome of the dental implant surgery and prosthetics. It was conducted at the Aga Khan University Hospital, Karachi, and comprised of medical charts and radiographic records of patients visiting between 2010 and 2015. Variables such as implant dimensions, final prosthesis, method of retention, loading protocol and patient factors were analysed. A total of 223 implants (143(64.1%) in maxilla and 80(35.9%) in mandible) were placed in 92 subjects (50(54.3%) males and 42(45.7%) females). All implants were Zimmer tapered screw-vent. Length of 108(48.4%) implants was 11.5mm and diameter …


Age Estimation Of A Sample Of Pakistani Population Using Coronal Pulp Cavity Index In Molars And Premolars On Orthopantomogram, Sheikh Bilal Badar, Rabia Ghafoor, Farhan Raza Khan, Muhammad Hasan Hameed Oct 2016

Age Estimation Of A Sample Of Pakistani Population Using Coronal Pulp Cavity Index In Molars And Premolars On Orthopantomogram, Sheikh Bilal Badar, Rabia Ghafoor, Farhan Raza Khan, Muhammad Hasan Hameed

Department of Surgery

The aim of the present study was to assess the validity of tooth-coronal index (TCI) in the age estimation. This retrospective charts review was conducted at the Aga Khan University Hospital, Karachi from January 2016 to March 2016, and comprised 315 teeth of 80 individuals. The teeth were analysed on Orthopantomogram. TCI was calculated for unrestored mandibular premolars and molars. Pearson's correlation was applied to assess correlation between chronological age and TCI. Besides, 30(37.5%) subjects were male and 50(62.5%) female, and 140(44.4%) teeth were of male subjects and 175(55.6%) were of females. The mean correlation coefficient between chronological age and …


A Review Of The Failed Cases Of Dental Implants At A University Hospital In Karachi, Farhan Raza Khan, Rabia Ali, Sana Ehsen Nagi Oct 2016

A Review Of The Failed Cases Of Dental Implants At A University Hospital In Karachi, Farhan Raza Khan, Rabia Ali, Sana Ehsen Nagi

Department of Surgery

Abstract

The retrospective study was conducted to assess the dental implants that experienced failure. It was conducted at the dental clinic of the Aga Khan University Hospital, Karachi, and comprised record of dental implants from July 2010 to June 2015. Variables such as patient age, gender and systemic status, length and diameter of implants, bone grafting, type of definitive prosthesis (crown or bridge or overdenture), nature of retention (cement versus screw retained), loading strategy (immediate versus delayed loading), etc. were analysed. Of the 220 implants placed, 6(2.7%) failed to integrate (as revealed by torque test) at the beginning of prosthetic …


Association Between Hypodontia And Angles Malocclusion, Batool A. Haider, Syed Sheeraz Hussain Oct 2016

Association Between Hypodontia And Angles Malocclusion, Batool A. Haider, Syed Sheeraz Hussain

Department of Surgery

Abstract

This study was planned to determine the prevalence of hypodontia in permanent dentition and to test whether an association was present between hypodontia and Angle's malocclusion. The retrospective study was conducted at a tertiary care hospital, Karachi, and comprised record of all patients visiting the orthodontic clinics of the hospital from 2005 to 2015. Orthodontic records of 790(79%) subjects, including 189(23.9%) males and 601(76.1%) females, were reviewed. Their mean age was 17 ± 5.06 years. A tooth was considered missing if no evidence of tooth germ was observed on orthopantomograms and dental casts. The total sample was distributed into …


Bilateral Radicular Cyst With Severe Destruction Of The Buccal Cortical Plate Secondary To Endodontic Failure, Rabia Ghafoor, Kiran Rehman Apr 2016

Bilateral Radicular Cyst With Severe Destruction Of The Buccal Cortical Plate Secondary To Endodontic Failure, Rabia Ghafoor, Kiran Rehman

Department of Surgery

Abstract

Large apical radiolucencies after endodontic treatment are usually advised orthograde retreatment, apical surgery and that too with a guarded prognosis. Microsurgical techniques, the use of ultrasonic and magnification aides, have been in use in the developed countries for the past few decades and have shown significant improvement in long-term success of such cases. MTA is proposed as one of the best materials for sealing root end surfaces. In this report, the healing response of cases of 2 large apical radiolucencies, found separately in the anterior maxilla, which were treated by orthograde as well as retrograde endodontic treatments and guided …


Effect Of Clark’S Twin-Block Appliance (Ctb) And Non-Extraction Fixed Mechano-Therapy On The Pharyngeal Dimensions Of Growing Children, Batool A. Haider, Attiya Shaikh, Mubassar Fida Nov 2015

Effect Of Clark’S Twin-Block Appliance (Ctb) And Non-Extraction Fixed Mechano-Therapy On The Pharyngeal Dimensions Of Growing Children, Batool A. Haider, Attiya Shaikh, Mubassar Fida

Department of Surgery

Abstract

INTRODUCTION:

Narrow airway dimensions due to mandibular deficiency can predispose an individual to severe respiratory distress. Hence, treatment with mandibular advancement devices at an early age might help improving the pharyngeal passage and reduce the risk of respiratory difficulties. Therefore, the aim of the current study was to evaluate the mean changes in the pharyngeal dimensions of children with mandibular deficiency treated with Clark's twin-block appliance (CTB) followed by fixed orthodontic treatment.

METHODS:

Orthodontic records of 42 children with mandibular deficiency were selected. Records comprised three lateral cephalograms taken at the start of CTB treatment, after CTB removal and …


Pycnodysostosis With Special Emphasis On Dentofacial Characteristics, Aisha Khoja, Mubassar Fida, Attiya Shaikh Nov 2015

Pycnodysostosis With Special Emphasis On Dentofacial Characteristics, Aisha Khoja, Mubassar Fida, Attiya Shaikh

Department of Surgery

Abstract

Pycnodysostosis is an autosomal recessive disorder that manifests as osteosclerosis of the skeleton due to the defective osteoclasts mediated bone turnover. The diagnosis of this disorder is established on the basis of its characteristic features and must be differentially diagnosed with other bone disorders. Dental surgeons should be aware of the limitations and possible adverse oral complications such as osteomyelitis of bone in these patients. This will guide them in planning realistic treatment goals. This paper reports the clinical and radiographic features of pycnodysostosis with the great emphasis on its dentofacial characteristics. The aim of this case report is …


Diagnosis Of Second Mesiobuccal Canal In Maxillary First Molars Among Patients Visiting A Tertiary Care Hospital., Muhammad Hasan Hameed, Farhan Raza Khan Jun 2015

Diagnosis Of Second Mesiobuccal Canal In Maxillary First Molars Among Patients Visiting A Tertiary Care Hospital., Muhammad Hasan Hameed, Farhan Raza Khan

Department of Surgery

No abstract provided.


Current Trends In Undergraduate Medical And Dental Research: A Picture From Pakistan, Waqar Jeelani, Sanaa Masood Aslam, Asrar Elahi Apr 2014

Current Trends In Undergraduate Medical And Dental Research: A Picture From Pakistan, Waqar Jeelani, Sanaa Masood Aslam, Asrar Elahi

Department of Surgery

Abstract

BACKGROUND:

Initiatives taken over the last few years have led us to the day when most of the medical and dental institutions in the developed countries have established a strong research culture at undergraduate level but the situation is quite the contrary in Pakistan. This study was carried out to investigate the current trends in undergraduate medical and dental research and to highlight the research barriers.

METHODS:

A cross-sectional study was conducted at six medical and dental colleges of Rawalpindi and Islamabad. A structured questionnaire was used to collect data from 300 students. Results were recorded as percentages. Findings …