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Investigating The Adherence Of Maternal Prenatal Vitamin Supplementation In Sarasota, Florida, Priya Darbhanga, Kaisha Mcmanus Apr 2024

Investigating The Adherence Of Maternal Prenatal Vitamin Supplementation In Sarasota, Florida, Priya Darbhanga, Kaisha Mcmanus

BIO4960: Practicum in Biology I

Prenatal supplementation plays a critical role in supporting a healthy pregnancy and lowering the risk of developmental problems in children. Many expecting mothers do not consume the recommended amounts of such vitamins or any at all. This study aims to identify and understand the factors that contribute to prenatal vitamin adherence amongst women at the Sarasota Medical Pregnancy Center located in Sarasota, Florida. Paper-based questionnaires were administered to all willing participants to assess the current adherence of women to prenatal supplementation and discover the reasonings for such decisions. The primary contributors to adherence to prenatal vitamins were related to a …


Denial Of Pregnancy Or Cryptic Pregnancy, Nadia N. Shuriah, Elaine Mcfarland, Bethany Spenn, Kaisha Butz Mcmanus Apr 2024

Denial Of Pregnancy Or Cryptic Pregnancy, Nadia N. Shuriah, Elaine Mcfarland, Bethany Spenn, Kaisha Butz Mcmanus

BIO4960: Practicum in Biology I

Denial of pregnancy, or cryptic pregnancy, presents a complex situation where individuals are unaware of their pregnancy until the late stages of labor. This study delves into the multifaceted nature of concealed and denied pregnancies, exploring their prevalence, factors contributing to them, and their implications for both individuals and healthcare systems. By reviewing relevant literature and case studies, we aim to illuminate the difficulties healthcare providers face in identifying and managing cases of denial of pregnancy. Additionally, we stress the significance of proactive screening and comprehensive care to ensure the well-being of mothers and infants. This research endeavors to deepen …


Neurological-Type Wilson Disease: Epidemiology, Clinical Manifestations, Diagnosis, And Management, Nathaniel Kipker, Kaitlyn Alessi, Marko Bojkovic, Inderbir Padda, Mayur S. Parmar Apr 2023

Neurological-Type Wilson Disease: Epidemiology, Clinical Manifestations, Diagnosis, And Management, Nathaniel Kipker, Kaitlyn Alessi, Marko Bojkovic, Inderbir Padda, Mayur S. Parmar

HPD Articles

Wilson disease (WD) is a complex metabolic disorder caused by disruptions to copper regulation within the body, leading to an unregulated accumulation of copper within various tissues. A less understood organ affected by the collection of copper is the brain, which further leads to the generation of oxygen-free radicals and resultant demyelination. Healthcare providers must keep the neurological form of WD in their list of differentials when patients present with diverse neurological manifestations. The initial step to diagnosis will be to distinguish the characteristic disease presentation with a thorough history and physical and neurological examination. A high clinical disease suspicion …


Abaloparatide, Miis Akel, Mayur Parmar Jan 2023

Abaloparatide, Miis Akel, Mayur Parmar

HPD Articles

No abstract provided.


Bazedoxifene, Parth M. Raina, Mayur Parmar Jan 2023

Bazedoxifene, Parth M. Raina, Mayur Parmar

HPD Articles

No abstract provided.


Romosozumab, Kristina Krupa, Mayur Parmar, Linda F. Delo Jan 2023

Romosozumab, Kristina Krupa, Mayur Parmar, Linda F. Delo

HPD Articles

No abstract provided.


A Case Of Transverse Myelitis Secondary To Covid-19 Infection, Rahul Borra, Neal T. Patel, Raheel Shaikh, Mayur S. Parmar, Sujatha Borra Dec 2022

A Case Of Transverse Myelitis Secondary To Covid-19 Infection, Rahul Borra, Neal T. Patel, Raheel Shaikh, Mayur S. Parmar, Sujatha Borra

HPD Articles

Infection with COVID-19 (SARS-CoV-2) is associated with a variety of generalized and specific symptoms, including neurological complications of both the peripheral and central nervous systems. In this case report, we present the case of a previously healthy 55-year-old woman who was diagnosed with transverse myelitis following a previous infection with COVID-19. MRI showed progressive demyelination of the cervical and thoracic spinal cord, and cerebrospinal fluid (CSF) showed increased levels of protein and red blood cells and no markers of infection, including negative polymerase chain reaction (PCR) for COVID-19 antibodies. The patient was treated with a course of methylprednisolone, multiple treatments …


Poststroke Seizure And Epilepsy: A Review Of Incidence, Risk Factors, Diagnosis, Pathophysiology, And Pharmacological Therapies, Joseph Phan, Mario Ramos, Theodore Soares, Mayur S. Parmar Oct 2022

Poststroke Seizure And Epilepsy: A Review Of Incidence, Risk Factors, Diagnosis, Pathophysiology, And Pharmacological Therapies, Joseph Phan, Mario Ramos, Theodore Soares, Mayur S. Parmar

HPD Articles

Stroke is the most common cause of epilepsy and ultimately leads to a decrease in the quality of life of those affected. Ischemic and hemorrhagic strokes can both lead to poststroke epilepsy (PSE). Significant risk factors for PSE include age less than 65 years, stroke severity measured by the National Institutes of Health Stroke Scale (NIHSS), cortical involvement, and genetic factors such as TRPM6 polymorphism. The diagnosis of PSE is made by using imaging modalities, blood biomarkers, and prognostic criteria. Electroencephalography (EEG) is currently the gold standard to diagnose PSE, while new combinations of modalities are being tested to increase …


Zoonosis At The Huanan Seafood Market: A Critique, Daoyu Zhang, Gilles Demaneuf, Adrian Jones, Steven Massey, Steven Quay, Yuri Deigin, Louis R. Nemzer Oct 2022

Zoonosis At The Huanan Seafood Market: A Critique, Daoyu Zhang, Gilles Demaneuf, Adrian Jones, Steven Massey, Steven Quay, Yuri Deigin, Louis R. Nemzer

Chemistry and Physics Faculty Proceedings, Presentations, Speeches, Lectures

Since the Hunan Seafood Market (HSM) in Wuhan, China was first suggested as the source of the COVID-19 pandemic in late January 2020, debate has continued over the evidence supporting this claim. Here, we assess the evidence provided in support of zoonotic spillover at the HSM as the origin of human infection of SARS-CoV-2. We find that the datasets and analyses put forward in support of zoonosis are biased, and lack sufficient verifiable data to support this hypothesis. The earliest COVID-19 case at the HSM was not at or near a wildlife stall, the distribution of cases at the HSM …


Effects Of Covid-19 On Pregnant Women And Newborns: A Review, Bhavesh M. Patel, Deepesh Khanna, Siya Khanna, Vera Hapshy, Pragya Khanna, Payal Kahar, Mayur S. Parmar Oct 2022

Effects Of Covid-19 On Pregnant Women And Newborns: A Review, Bhavesh M. Patel, Deepesh Khanna, Siya Khanna, Vera Hapshy, Pragya Khanna, Payal Kahar, Mayur S. Parmar

HPD Articles

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus originated in Wuhan, China, and spread all over the world, causing the worst pandemic of the century. The disease has a broad continuum of clinical presentations, from mild to life-threatening. The virus is highly contagious and transmittable to humans. Emerging evidence of its effects on pregnant women and newborns is inconsistent and ever-evolving. Therefore, the objective of this review is to compile the scientific literature on the effects of SARS-CoV-2 coronavirus on pregnancy, pregnant women, and newborns. Data were obtained by several authors using PubMed, MEDLINE, Google Scholar, and Web …


A Review Of Covid-19 In Relation To Metabolic Syndrome: Obesity, Hypertension, Diabetes, And Dyslipidemia, Elias Makhoul, Joseph L. Aklinski, Jesse Miller, Cara Leonard, Sean Backer, Payal Kahar, Mayur S. Parmar, Deepesh Khanna Jul 2022

A Review Of Covid-19 In Relation To Metabolic Syndrome: Obesity, Hypertension, Diabetes, And Dyslipidemia, Elias Makhoul, Joseph L. Aklinski, Jesse Miller, Cara Leonard, Sean Backer, Payal Kahar, Mayur S. Parmar, Deepesh Khanna

HPD Articles

Although severe cases and mortality of coronavirus disease 2019 (COVID-19) are proportionally infrequent, these cases are strongly linked to patients with conditions of metabolic syndrome (obesity, hypertension, diabetes, and dyslipidemia). However, the pathophysiology of COVID-19 in relation to metabolic syndrome is not well understood. Thus, the goal of this secondary literature review was to examine the relationship between severe acute respiratory syndrome (SARS-CoV-2) infection and the individual conditions of metabolic syndrome. The objective of this secondary literature review was achieved by examining primary studies, case studies, and other secondary studies, to obtain a comprehensive perspective of theories and observations of …


Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar Feb 2022

Body Mass Index (Bmi): A Screening Tool Analysis, Deepesh Khanna, Cadynce Peltzer, Payal Kahar, Mayur S. Parmar

HPD Articles

Body mass index (BMI), a measurement based on a person's height and weight, allows the classification of individuals into categories such as obese or overweight. With these classifications, we can assess risk for hypertension, diabetes, cancer, hypercholesterolemia, and other chronic diseases. Furthermore, childhood BMI serves as a prediction method for health and disease later in life. Along with BMI, researchers also study waist circumference and waist-to-hip ratio in correlation with the above-mentioned chronic illnesses. This brief review explores the associations between body mass index, waist circumference, and the waist-hip ratio as measurements and their capability as predictors for persistent conditions …


Impacts Of Covid-19 On Global Healthcare Management And Research, Stephanie Autore, Santanu De Jan 2022

Impacts Of Covid-19 On Global Healthcare Management And Research, Stephanie Autore, Santanu De

Biology Faculty Articles

The Coronavirus Infectious Disease 2019 (COVID-19) pandemic has affected most nations at all levels of functioning, individual to governmental. Therefore, it is imperative to evaluate the effects the virus has had on one of the most important socioeconomic global sectors, healthcare. This literature review explores key, recent research and management strategies that have been undertaken in healthcare systems around the world in order to make meaningful attempts at identifying the etiology, diagnosis, and treatment of the disease, and combating the spread of this deadly virus. Healthcare facilities have implemented a variety of changes, all geared towards reducing non-emergency patient visits …


Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar Jan 2022

Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.


Golimumab, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2022

Golimumab, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar Jan 2022

Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.


Poststroke Seizure And Epilepsy: A Review Of Incidence, Risk Factors, Diagnosis, Pathophysiology, And Pharmacological Therapies, Joseph Phan, Mario Ramos, Theodore Soares, Mayur S. Parmar Jan 2022

Poststroke Seizure And Epilepsy: A Review Of Incidence, Risk Factors, Diagnosis, Pathophysiology, And Pharmacological Therapies, Joseph Phan, Mario Ramos, Theodore Soares, Mayur S. Parmar

HPD Articles

Stroke is the most common cause of epilepsy and ultimately leads to a decrease in the quality of life of those affected. Ischemic and hemorrhagic strokes can both lead to poststroke epilepsy (PSE). Significant risk factors for PSE include age < 65age less than 65 years, stroke severity measured by the National Institutes of Health Stroke Scale (NIHSS), cortical involvement, and genetic factors such as TRPM6 polymorphism. The diagnosis of PSE is made by using imaging modalities, blood biomarkers, and prognostic criteria. Electroencephalography (EEG) is currently the gold standard to diagnose PSE, while new combinations of modalities are being tested to increase diagnostic specificity. This literature review uncovers a newly found mechanism for the pathology of poststroke epilepsy. The pathogenesis of early-onset and late-onset is characterized by sequelae of neuronal cellular hypoxia and disruption of the blood-brain barrier, respectively. Interleukin-6 is responsible for increasing the activity of glial cells, causing gliosis and hyperexcitability of neurons. Epinephrine, high-mobility group protein B1, downregulation of CD32, and upregulation of HLA-DR impact the pathology of poststroke epilepsy by inhibiting the normal neuronal immune response. Decreased levels of neuropeptide Y, a neurotransmitter, act through multiple unique mechanisms, such as inhibiting intracellular Ca accumulation and acting as an anti-inflammatory, also implemented in the worsening progression of poststroke epilepsy. Additionally, CA1 hippocampal resonant neurons that increase theta oscillation are associated with poststroke epilepsy. Hypertensive small vessel disease may also have an implication in the temporal lobe epilepsy by causing occult microinfarctions. Furthermore, this review highlights the potential use of statins as primary prophylaxis against PSE, with multiple studies demonstrating a reduction in incidence using statins alone, statins in combination with antiepileptic drugs (AEDs), and statins with aspirin. The evidence strongly suggests that the second generation AEDs are a superior treatment method for PSE. Data from numerous studies demonstrate their relative lack of significant drug interactions, increased tolerability, and potential superiority in maintaining seizure-free status.


The Link Between Diabetes Mellitus And Tau Hyperphosphorylation: Implications For Risk Of Alzheimer's Disease, Amy L. Hobday, Mayur S. Parmar Sep 2021

The Link Between Diabetes Mellitus And Tau Hyperphosphorylation: Implications For Risk Of Alzheimer's Disease, Amy L. Hobday, Mayur S. Parmar

HPD Articles

Diabetes mellitus (DM) is characterized by hyperglycemia caused by a lack of insulin, insulin resistance, or both. It is associated with the development of secondary complications resulting in several comorbidities. Recent studies have revealed an increased risk of developing cognitive dysfunction or dementia in diabetes patients. Diabetes mellitus is considered a risk factor for many neurodegenerative diseases, including Alzheimer's disease (AD). There is increasing evidence to support a link between DM and AD. Studies have shown the dysfunction of insulin signaling in the brain, resulting in increased tau protein phosphorylation (hyperphosphorylation), a hallmark and biomarker of AD pathology, leading to …


Epidemiology, Pathogenesis, And Clinical Manifestations Of Acute Esophageal Necrosis In Adults, Obaid Rehman, Urooj Jaferi, Inderbir Padda, Nimrat Khehra, Harshan Atwal, Mayur Parmar Jul 2021

Epidemiology, Pathogenesis, And Clinical Manifestations Of Acute Esophageal Necrosis In Adults, Obaid Rehman, Urooj Jaferi, Inderbir Padda, Nimrat Khehra, Harshan Atwal, Mayur Parmar

HPD Articles

Acute esophageal necrosis (AEN), also termed "black esophagus," is a unique and uncommon occurrence observed in severely sick patients. Other terminologies include acute necrotizing esophagitis and Gurvits syndrome. This condition is described as a darkened distal third of the esophagus observed on endoscopy and presents as an upper gastrointestinal (GI) bleed, difficulty swallowing, abdominal pain, fever, syncope, nausea, and vomiting. The etiology of AEN has been linked to several possibilities, such as excessive gastric acid reflux, hypoperfusion, and ischemia due to impaired vascular supply and hemodynamic instability. Risk factors include increased age, sex (male), heart disease, hemodynamic insufficiency, alcohol use, …


Evaluating The Effects Of Physical Activity On The Cognitive Functions And Motor Skills Of The Special Needs Population And Testing A Different Teaching Style To Maximize The Efficiency Of Special Needs Programs, Oren Nedjar Jun 2021

Evaluating The Effects Of Physical Activity On The Cognitive Functions And Motor Skills Of The Special Needs Population And Testing A Different Teaching Style To Maximize The Efficiency Of Special Needs Programs, Oren Nedjar

BIO4960: Practicum in Biology I

This study aimed to analyze the effects of physical activities on the motor and cognitive functions of participants with special needs and compare these results with a similar program but organized online because of the health precautions that have been applied due to the COVID-19 pandemic. An intervention consisting of sending an educational brochure aiming to increase high school volunteers' health literacy was then tested and results showed that it improved participants' health outcomes and also could increase the program's effectiveness in the long term.


Biosimilars Use In Medicine For Inflammatory Diseases, Inderbir S. Padda, Rajat Bhatt, Obaid Rehman, Mayur S. Parmar Jan 2021

Biosimilars Use In Medicine For Inflammatory Diseases, Inderbir S. Padda, Rajat Bhatt, Obaid Rehman, Mayur S. Parmar

HPD Articles

No abstract provided.


Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Aducanumab, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Aducanumab, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Apremilast, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Apremilast, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Pegloticase, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Pegloticase, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Tofacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Tofacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Upadacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Upadacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Lenvatinib, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Lenvatinib, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Obeticholic Acid, Kristina Krupa, Vera Hapshy, Hiep Nguyen, Mayur S. Parmar Jan 2021

Obeticholic Acid, Kristina Krupa, Vera Hapshy, Hiep Nguyen, Mayur S. Parmar

HPD Articles

No abstract provided.


Health Communication Toolkit Case Competition, Halmos College Of Arts And Sciences (Hcas) Oct 2020

Health Communication Toolkit Case Competition, Halmos College Of Arts And Sciences (Hcas)

HCAS Case Competitions

No abstract provided.