Medicine and Health Sciences Commons^™

Ultraviolet Action Spectroscopy Of Iodine Labeled Peptides And Proteins In The Gas Phase, Benjamin B. Kirk, Adam J. Trevitt, Stephen J. Blanksby, Yuanqi Tao, Benjamin N. Moore, Ryan Julian

Adam Trevitt

Structural investigations of large biomolecules in the gas phase are challenging. Herein, it is reported that action spectroscopy taking advantage of facile carbon-iodine bond dissociation can be used to examine the structures of large molecules, including whole proteins. Iodotyrosine serves as the active chromophore, which yields distinctive spectra depending on the solvation of the side chain by the remainder of the molecule. Isolation of the chromophore yields a double featured peak at 290 nm, which becomes a single peak with increasing solvation. Deprotonation of the side chain also leads to reduced apparent intensity and broadening of the action spectrum. The …

Strategies To Address Iodine Deficiency In Australia Require Ongoing Monitoring And Surveillance, Heather Yeatman, Karen E. Charlton

Karen E. Charlton

No abstract provided.

Improved Iodine Status In Breastfeeding Women Following Mandatory Fortification, Samantha Axford, Karen Charlton, Heather Yeatman, Gary Ma

Karen E. Charlton

Mandatory iodine fortification of salt used in the bread-making process was introduced in Australia in October 2009 at levels to meet the iodine needs of the general Australian population. An iodine supplement of 150 μg each day is recommended to meet the additional needs of pregnancy and lactation.1,2 As the iodine status of pregnant women in Australia has been found to be inadequate,3–5 it can be anticipated that many women commence lactation in an iodine-depleted state. Thus, it is important to determine the iodine status of breastfeeding mothers.

Iodine Fortification: Why, When, What, How, And Who?, Karen Charlton, Sheila Skeaff

Karen E. Charlton

Purpose of review: To highlight current issues regarding the role of iodine fortification in correcting and preventing iodine deficiency. Universal salt iodization (USI) is recommended, wherein all salt is iodized; however, a more graduated approach may be warranted.Recent findings: Iodine deficiency is widespread and has re-emerged in countries such as Australia, New Zealand and the UK. As well as supplementation in groups such as pregnant and lactating women who have increased iodine requirements, public health strategies to improve iodine intakes include voluntary or mandatory fortification of the food supply. A key player in the process of fortification is the food …

Poor Knowledge And Practices Related To Iodine Nutrition During Pregnancy And Lactation In Australian Women: Pre-And Post-Iodine Fortification, Karen Charlton, Heather Yeatman, Catherine Lucas, Samantha Axford, Luke Gemming, Fiona Houweling, Alison Goodfellow, Gary Ma

Karen E. Charlton

A before-after review was undertaken to assess whether knowledge and practices related to iodine nutrition, supplementation and fortification has improved in Australian women since the introduction of mandatory iodine fortification in 2009. Surveys of pregnant (n = 139) and non-pregnant (n = 75) women in 2007-2008 are compared with surveys of pregnant (n = 147) and lactating women (n = 60) one to two years post-fortification in a regional area of New South Wales, Australia. A self-administered questionnaire was completed and dietary intake of iodine was assessed using a validated food frequency questionnaire. A generally poor knowledge about the role …

Poor Iodine Status And Knowledge Related To Iodine On The Eve Of Mandatory Iodine Fortification In Australia, Heather Yeatman, Karen E. Charlton, Fiona Houweling

Karen E. Charlton

Background: Mandatory fortification of bread with iodised salt is proposed to address the re-emergence of iodine deficiency in Australia and New Zealand. The impacts of fortification require baseline data of iodine status among vulnerable sectors of the population. Objective: To assess the iodine status of healthy women and to investigate consumer understanding and attitudes related to the proposed mandatory iodine fortification programme. Design: Cross-sectional sample of 78 non-pregnant women aged 20-55 y was conveniently sampled in Wollongong, NSW. A single 24-hr urine sample was collected for urinary iodine concentration (UIC). A selfadministered questionnaire assessed consumer understanding, perceptions and attitudes related …

Poor Knowledge And Dietary Practices Related To Iodine In Breastfeeding Mothers A Year After Introduction Of Mandatory Fortification, Samantha Axford, Karen Charlton, Heather Yeatman, G Ma

Karen E. Charlton

No abstract provided.

A Lowered Salt Intake Does Not Compromise Iodine Status In Cape Town, South Africa, Where Salt Iodization Is Mandatory, Karen Charlton, Pieter Jooste, Krisela Steyn, Naomi Levitt, Abhijeet Ghosh

Karen E. Charlton

Objective Universal salt iodization is an effective strategy to optimize population-level iodine. At the same time as salt-lowering initiatives are encouraged globally, there is concern about compromised iodine intakes. This study investigated whether salt intakes at recommended levels resulted in a suboptimal iodine status in a country where salt is the vehicle for iodine fortification.

Methods Three 24-h urine samples were collected for the assessment of urinary sodium and one sample was taken for urinary iodine concentrations (UICs) in a convenience sample of 262 adult men and women in Cape Town, South Africa. Median UIC was compared across categories of …