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Full-Text Articles in Medicine and Health Sciences
Anesthesia Of The Geriatric Equine, Reza Seddighi Dvm, Ms, Phd, Dip Acva, Cvma
Anesthesia Of The Geriatric Equine, Reza Seddighi Dvm, Ms, Phd, Dip Acva, Cvma
Reza Seddighi
Advancements in veterinary medicine have resulted in an increased number of geriatric horses being presented for medical or surgical procedures that require general anesthesia. Due to the physiological changes associated with aging and the likelihood of concurrent disease conditions, the geriatric equine is at an increased risk during anesthesia. The main physiological changes associated with aging, and their impact on anesthesia, are discussed in this review.
The Effect Of Midazolam On End-Tidal Concentration Of Isoflurane Necessary To Prevent Movements In Dogs, Reza Seddighi Dvm, Ms, Phd, Dip Acva
The Effect Of Midazolam On End-Tidal Concentration Of Isoflurane Necessary To Prevent Movements In Dogs, Reza Seddighi Dvm, Ms, Phd, Dip Acva
Reza Seddighi
Objective To determine the possible additive effect of midazolam, a GABAA agonist, on the end-tidal concentration of isoflurane that prevents movement (MACNM) in response to noxious stimulation. Study design Randomized crossover experimental study. Animals Six, healthy, adult intact male, mixed-breed dogs. Methods After baseline isoflurane MACNM (MACNM-B) determination, midazolam was administered as a low (LDS), medium (MDS) or high (HDS) dose series of midazolam. Each series consisted of two dose levels, low and high. The LDS was a loading dose (Ld) of 0.2 mg kg-1 and CRI (2.5 μg kg-1 minute-1) (LDL), followed by an Ld (0.4 mg kg-1) and …
Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva
Local Anesthetics As Pain Therapy In Horses, Reza Seddighi Dvm, Ms, Phd, Dip Acva
Reza Seddighi
Local Anesthetics as Pain Therapy in Horses Thomas J. Doherty MVB, MSc, and M. Reza Seddighi DVM, PhD
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, The University of Tennessee, 2407 River Drive, Knoxville, TN 37996, USA
This article describes the rationale behind the use of systemically administered lidocaine as an analgesic. The analgesic efficacy of intravenously administered lidocaine is well documented by studies in human patients and laboratory animals. The mechanism by which systemically administered lidocaine produces analgesia is uncertain but is thought to include action at sodium, calcium, and potassium channels and the N-methyl-D-aspartate acid receptor. …