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Bronchiolar Metaplasia And Ulex Europaeus Agglutinin I (Uea-I) Affinity In Mycoplasma Hyopneumoniae-Infected Lungs Of Six Pigs, Mark R. Ackermann, M. C. Debey, B. M. Debey
Bronchiolar Metaplasia And Ulex Europaeus Agglutinin I (Uea-I) Affinity In Mycoplasma Hyopneumoniae-Infected Lungs Of Six Pigs, Mark R. Ackermann, M. C. Debey, B. M. Debey
Mark R. Ackermann
Mycoplasma hyopneumoniae adheres to the cilia and apical plasma membrane of cells that line the trachea, bronchi, and bron ch ioles. Colonization result s in ciliostasis and peribronchial and peribronchi olar nod ular aggregates of lymphocytes and plasma cells.">Altho ugh adhesion-receptor interaction s between the organism and respiratory epithelial cells have been examined, little attention has been given to the morphologic and phenotypic changes that may occur in cells lining bron chioles during infection. In this study, we describe morphologic cha nges and differenc es in lectin staining patt ern s in the bron chi oles from lungs of …
Lectin Histochemistry Of Trachea And Lung Of Healthy Turkeys (Meleagris Gallopavo) And Turkeys With Pneumonia, Mark R. Ackermann, N. F. Cheville, P. G. Detilleux
Lectin Histochemistry Of Trachea And Lung Of Healthy Turkeys (Meleagris Gallopavo) And Turkeys With Pneumonia, Mark R. Ackermann, N. F. Cheville, P. G. Detilleux
Mark R. Ackermann
Thirteen lectins were used to characterize lectin-binding specificity of glycoconjugates on sections of formalin-fixed lung and trachea from seven normal turkeys, two turkeys with acute pneumonia, and two turkeys with chronic pneumonia. Neuraminidase was used to digest sialic acid residues. One N-acetylgalactosamine-binding lectin and two N-acetylgalactosamine/galactose-binding lectins stained the apical membrane and cytoplasm of multifocal cells that lined air atria and hyperplastic granular cells. Other lectins in these groups stained ciliated cells of the trachea and bronchi and air capillary epithelial cells. Sialic acid residues were on apical surfaces of ciliated and nonciliated tracheal and bronchial lining cells, air capillary …