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Full-Text Articles in Medicine and Health Sciences
Malignant Giant-Cell Tumor Of Bone With Lymph Node Involvement In A Cat, Ahmet Akkoç, Gürsel Sönmez, Kemal Yanik, Ayli̇n Alasonyalilar Demi̇rer, Ni̇hal Y. Gül, M. Carmen Ferreras-Estrada
Malignant Giant-Cell Tumor Of Bone With Lymph Node Involvement In A Cat, Ahmet Akkoç, Gürsel Sönmez, Kemal Yanik, Ayli̇n Alasonyalilar Demi̇rer, Ni̇hal Y. Gül, M. Carmen Ferreras-Estrada
Turkish Journal of Veterinary & Animal Sciences
The present study describes giant-cell tumor of bone (GCToB) with lymph node involvement in a 5-year-old crossbred cat. The animal was referred to the surgery clinic with progressive subcutaneous swelling in the left proximal femoral region, severe lameness, constipation, and dysuria. A moderately firm, subcutaneous, palpable mass, 9 cm in diameter, was observed, and biopsy samples were taken. Histopathologically, the mass was constituted by ovoid-shaped mononuclear cells intermixed with many multinucleated giant cells (MGC). Immunohistochemically, the giant cells were positively stained with antivimentin, and the same cells were negative for antidesmin and anti-S100 staining. Tartrate-resistant acid phosphatase (TRAP) activity in …
Pathological And Immunohistochemical Evaluation Of The Effects Of Interferon Gamma (Ifn-Γ) And Aminoguanidine In Rats Experimentally Infected With Fasciola Hepatica, Enver Beytut, Ati̇la Akça, Hali̇l İbrahi̇m Gökce
Pathological And Immunohistochemical Evaluation Of The Effects Of Interferon Gamma (Ifn-Γ) And Aminoguanidine In Rats Experimentally Infected With Fasciola Hepatica, Enver Beytut, Ati̇la Akça, Hali̇l İbrahi̇m Gökce
Turkish Journal of Veterinary & Animal Sciences
The present study was aimed at pathologically and immunohistochemically evaluating the effects of interferon gamma (IFN-\gamma) and aminoguanidine (AG) in rats experimentally infected with Fasciola hepatica. A total of 44 Wistar rats were divided into 4 groups. With the exception of the controls (fourth group), the remaining rats were infected orally with 25 metacerceria of F. hepatica. The first group was administered 0.2% AG in drinking water daily, in order to block nitric oxide (NO) production. The second group was administered 250 units of IFN-\gamma daily, in order to stimulate NO synthesis. The third group was administered a placebo only. …