Medicine and Health Sciences Commons^™

Parental Involvement During Adolescence And Contraceptive Use In College, Caroline Payne Purvis, Rosemary V. Barnett, Larry Forthun

Journal of Adolescent and Family Health

The current study aimed to explore the relationships between parental involvement during adolescence on sexual behaviors among college students. Research has shown that parental involvement decreases as students move from high school to college, but the impact that parents had on their students while in high school continues into college. It is important to determine if one factor relating to the number of sexual partners, sexual activity, and contraceptive use is parental involvement during adolescence. After approval from the Institutional Review Board (IRB), an online survey using Survey Monkey was administered to a convenience sample of undergraduate students in a …

Autoantibodies To The Ny-Eso-1 Tumor Antigen In Metastatic Melanoma: Sialylation Of The Fc Region Of Immunoglobulin G Induces Differential Expression Signatures Of Inflammatory Molecules During Dendritic Cell Differentiation And Maturation, Martin Oaks, Nathaniel Rein, John O. Richards, James Shaffer

Journal of Patient-Centered Research and Reviews

Purpose: We tested the hypothesis that different glycoforms of antibodies from patients with metastatic melanoma have different functional effects on human dendritic cell differentiation and maturation.

Methods: Antibodies to the cancer antigen NY-ESO-1 were affinity-purified from patients with melanoma and further fractionated into different glycoforms by lectin chromatography. Sialic acid-rich and sialic acid-poor fractions of these immunoglobulin G antibodies (IgG) were added to dendritic cell cultures during both differentiation and maturation, and the resulting cellular messenger RNA (mRNA) and culture supernatants were tested by microarray and enzyme-linked immunoassay for molecules related to inflammatory pathways.

Results: We identified unique mRNA and …

Full Issue, Volume 2, Number 3, Journal Of Human Sciences And Extension

Journal of Human Sciences and Extension

No abstract provided.

Human Papillomavirus And The Gardasil Vaccine: Medicalization And The Gendering Of Bodies And Bodily Risk, Lauren Camara

Laurier Undergraduate Journal of the Arts

No abstract provided.

Mapping Regions Of Rnf168 Required For Its Degradation By Icp0, Andrea Cyr, Matthew Weitzman

e-Research: A Journal of Undergraduate Work

Viruses establish infection by overtaking host cell processes and developing mechanisms that promote viral replication. Herpes simplex virus undergoes lytic and latent cycles of infection throughout the lifespan of its host. The viral genome is transcriptionally silent during latency, but viral proteins are produced upon reactivation. Herpes simplex virus type 1 encodes the ICP0 protein, an E3 ubiquitin ligase required for reactivation from latency of the infectious virus. The immediate-early protein ICP0 regulates the herpes simplex virus by activating viral gene expression thereby initiating lytic infection. Cellular proteins are degraded by ICP0, promoting the virus to enter the lytic cycle. …

Treating Cocaine Dependency With Psychopharmacotherapy And Behavioral Therapy, Robyn Liebman

e-Research: A Journal of Undergraduate Work

Cocaine is an addictive drug that affects more than 14 million people globally, according to the United Nations. This paper is a conceptual meta-analysis of numerous studies that tested the effects of psychopharmacological therapy along with behavioral therapy in the treatment of cocaine addiction. It is hypothesized that cocaine dependent individuals treated with a combination of psychopharmacological and behavioral therapies will be less likely to use cocaine. Measurements of cocaine use throughout the experiments were generally assessed by urine screenings. Results indicate that there is more evidence that a combination of psychopharmacological and behavioral therapies will reduce cocaine use. There …

The Effect Of Pomegranate Juice Extract On The Hedgehog Signaling Pathway In Pancreatic Cancer, Veronica Gomez, Talia Shackelford, Autumn Tocchi, Melissa Rowland-Goldsmith

e-Research: A Journal of Undergraduate Work

Pancreatic cancer is the fourth leading cause of cancer death in the United States. There have been several reports indicating that phytochemicals in fruits can reduce the risk of cancer due to the anti-oxidant and anti-inflammatory effects of the polyphenols. Our lab has shown that pomegranate juice extract (PJE) has anti-proliferative and pro-apoptotic effects in human pancreatic cancer cells. In the past, we have shown that cells adhere more strongly to the plate when treated with PJE. This observation prompted an investigation of how PJE regulates cell adhesion proteins. Previously, our lab investigated E-cadherin, a cell adhesion protein. Upon activation …

2014 Scas Annual Meeting Program

Journal of the South Carolina Academy of Science

No abstract provided.

Genotypic And Phenotypic Characterization Of Aerosolized Bacteria Collected From African Dust Events, Christina A. Wilson, Robin L. Brigmon, Chris Yeager, Garriet W. Smith, Shawn W. Polson

Journal of the South Carolina Academy of Science

Twenty-one bacteria were isolated and characterized from air samples collected in Africa and the Caribbean by the United States Geological Survey (USGS). Isolates were selected based on preliminary characterization as possible pathogens. Identification of the bacterial isolates was achieved using 16S rRNA gene sequence analysis, fatty acid methyl esters (FAMEs) profiling, the BIOLOG Microlog^® System (carbon substrate assay), and repetitive extragenic palindromic (REP)-PCR analysis. The majority of isolates (18/21) were identified as species of the genus Bacillus. Three isolates were classified within the Bacillus cereus senso lato group, which includes Bacillus anthracis, Bacillus thuringiensis, and Bacillus …

Remembering To Perform Actions In The Future: Can Intentions Pop Into Mind?, Gilles O. Einstein

Journal of the South Carolina Academy of Science

No abstract provided.

Role Of Vitamin A In Retinal Diseases, Rosalie K. Crouch, Masahiro Kono, Peter H. Tang

Journal of the South Carolina Academy of Science

Vitamin A has an essential role in vision in that it forms the photosensitive pigments that absorb light and initiate the visual process. However, vitamin A and its analogues also have critical roles in maintaining the structural integrity of the retina. Disruption of the metabolism of vitamin A results in several blinding diseases. This review focuses on our recent studies on the role of a protein critical to the processing of vitamin A, RPE65. The absence or dysfunction of this protein causes the childhood blinding disease Leber congenital amaurosis.

Scas Officers And Council Members 2014-2015

Journal of the South Carolina Academy of Science

No abstract provided.

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Food Insecurity And Psychological Well-Being Among Women Living With Hiv/Aids On Antiretroviral Therapy In The Alabama Black Belt, Andrew A. Zekeri, Youssouf Diabate

Professional Agricultural Workers Journal

The objective of this research was to estimate the prevalence of food insecurity and determine if food insecurity is associated with psychological well-being among women living with HIV/AIDS. Survey data were collected from 268 women living with HIV/AIDS attending two clinics that provide medical and social support services to HIV-positive patients who live in 23 counties in Southeast Alabama. The results indicated that, using USDA food security scale, 54% of the women were food insecure. Multiple regression analysis results indicated that income, depressive symptoms, race, and participation in SNAP were significant predictors of food insecurity; employment and education were not …

Biofeedback Relaxation Techniques In Addressing Cortex-Hypothalamus Control Loop For Motivation Of Obesity Avoidance, Liljana Bozinovska, Ahmed Majekodunmi

Professional Agricultural Workers Journal

This research explores how the achievement motivation pathway in the cortex influences hypothalamic activity, which could influence appetite control and obesity avoidance. The objective was to examine the sympathetic/parasympathetic feedback loop, and the influence of various biofeedback relaxation techniques on lowering heart rate (HR) and electrodermal activity (EDA). The methodology used was a standard biofeedback mechanism with visual representation of the measured physiological parameters. The feedforward part of the said feedback loop is controlled by hypothalamus while the feedback part is evaluated by the cortex. The participants were young adults and the sample size was ten. The results revealed that …

Fall 2014

Scientia

CSH progress notes; Alumna entrepreneur finds success at the intersection of chemistry and law; Lions, lycopods and laboratories: CSH students thrive in summer internships; Fielding a team for a mission to Mars; Professor Craig Klugman on the medical humanities; Lab Notes

Quest: Creating A Biotechnology Workforce Pipeline, Lynette Hazleton Mph

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Maine’S Contested Waterfront: The Project To Remake Sebago Lake’S Lower Bay, 1906-1930, David B. Cohen

Maine History

Throughout the nation’s history, few resources have been considered as ubiquitous as water. The issue of who controls the use of water, however, has seldom been straight forward. This was no less true in the Progressive Era, when many growing urban areas significantly altered their water infrastructure to meet increased demands. When debate arose over water use, these municipalities often relied on the relatively new authority of scientific knowledge, particularly in the area of public health and safety. In this article, the author describes how the Portland Water District was able to conserve Sebago Lake’s Lower Bay as a clean, …

Full Issue, Volume 2, Number 2, Journal Of Human Sciences And Extension

Journal of Human Sciences and Extension

No abstract provided.

Fty720 (Fingolimod) Provides Insight Into The Molecular Mechanisms Of Multiple Sclerosis, Madelyn Elizabeth Crawford

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

Multiple sclerosis (MS) is a neurodegenerative disorder caused by a prolonged immune- mediated inflammatory response that targets myelin. Nearly all of the drugs approved for the treatment of MS are general immunosuppressants or only function in symptom management. The oral medication fingolimod, however, is reported to have direct therapeutic effects on cells of the central nervous system in addition to immunomodulatory functions. Fingolimod is known to interact with sphingosine-1-phosphate (S1P) receptors, and the most widely- accepted theory for its mechanism of action is functional antagonism of the receptor. This review examines significant neuromodulatory effects achieved by functional antagonism of the …

How Do Management Treatments Affect Invasive Cattail (Typha X Glauca) And Pore Water Nutrient Concentrations?, Yarency Rodriguez

DePaul Discoveries

Invasive species are problematic for wetland managers, but little is known about how common management treatments influence nutrient cycling or plant responses. This study tested three experimental treatments (mowing, herbiciding, and harvesting (i.e., removal of aboveground biomass)) on several response variables: wetland soil porewater nutrient content (NO₃^-, NH₄⁺, PO₄^-), native plant and invasive-Typha density, and light attenuation through the plant canopy. Seventeen days post-treatment, herbiciding resulted in higher porewater phosphate concentrations (55.63 µg-P/L) than harvesting (8.95 µg-P/L). After 24 days, herbicide had higher porewater phosphate concentration (72.03 µg-P/L) than all …

Investigating The Viability Of Two Stenotrophomonas Maltophilia Isolates After Air-Drying, Samantha Lane, Joanna Brooke

DePaul Discoveries

Abstract

Stenotrophomonas maltophilia is a water-borne infectious bacterium that is found in both clinical (hospitals) and non-clinical environments. This human pathogen is commonly recovered from respiratory tract infections. A recent study at a hospital in Taiwan suggested that dry patient charts can serve as a vehicle of transmission of this bacterium⁷. As S. maltophilia is not commonly isolated from dry surfaces, this current study tested the hypothesis that this pathogen can remain viable for some time on a dry surface. This study was designed to determine how long S. maltophilia could remain viable after air-drying by observing …

Dreams And Learning, Cody Mebane Gibbons

Symposium

Project Summary: This study is being done to test one aspect of how paying attention to one’s dreams may influence our waking lives. The idea was inspired by research linking the brain processes involved in long-term memory storage to qualities of dreaming, as well as the potential for learning in lucid dreams. It is hypothesized that the more conscious one is of one’s dreams and dream world, the better one will be at learning. In order to test this, the dreaming ability of 300 Cal Poly students will be analyzed via dream questionnaires with the purpose of seeing if any …

Characterizing The Response Of Multidrug-Resistant Klebsiella Pneumoniae Species To The Application Of A Phage Cocktail, Steven Liu

Symposium

Project Summary: The application of bacteriophages to treat bacterial infections is known as phage therapy, which takes advantage of bacteriophage’s natural ability to infect and lyse bacterial hosts. Phages have been shaped by billions of years of evolution to be highly specialized deliverers of bactericidal agents to the cytoplasm of their target bacteria. Ever since discovery of bacteriophages in 1915, phage therapy was recognized as a potentially powerful tool for eliminating bacterial infections. The effectiveness of phage therapy can be increased by creating a mixture of multiple phages to target a wider variety of bacterial strains. Furthermore, phage therapy has …

The Compass, Issue 1, Arcadia University Honors Program

The Compass

Issue 1 of The Compass, a scholarly journal edited and produced by students in the Arcadia University Honors Program.

Analysis Of The Morbidity And Mortality Of Severe Influenza Infection In Clark County, Nevada For The 2010-2011 Influenza Season, Kindra St. Jacques, Patricia Cruz, Brian Labus

Nevada Journal of Public Health

Throughout the duration of any influenza season, influenza strains have the ability to evolve through mutation causing alterations in virulence. These changes may result in severe illness or death among susceptible populations; therefore, it is important to closely monitor influenza-associated hospitalizations and deaths. The University of Nevada, Las Vegas in collaboration with the Southern Nevada Health District analyzed data from the hospitalized influenza morbidity and mortality surveillance project for Clark County for the 2010-2011 influenza season. Among the study population (N= 158): the influenza strain type was found to be significantly associated with deaths (n= 25), vaccination status was not …

Environmental Correlates Of Physical Activity Among African-American Adults, Tim Bungum, Jennifer Pharr, Paulo S. Pinheiro, Maria Azzarelli

Nevada Journal of Public Health

The purpose of this cross-sectional study was to identify perceived environmental correlates of meeting physical activity guidelines among African-American adults living in Southern Nevada. Trained interviewers phoned potential participants who lived in the 12 zip codes of Clark County, Nevada with the highest proportions of African-American residents. Respondents (n=237) answered 52 health-related and demographic questions. Slightly less than 50% of participants met physical activity guidelines. A factor analysis procedure produced two environmental variables, neighborhood safety and environmental supports for physical activity. Age, gender and educational attainment (p<.05) predicted the meeting of those guidelines (R2=.214), while neighborhood support for physical activity, neighborhood safety, and BMI failed to do so. This finding suggests that environmental factors are not strong predictors of physical activity among African- American adults, although environmental supports for physical activity approached significance. Future studies should consider assessing additional aspects of the built environment as an influence on physical activity.

Best Integrated Writing 2014 - Complete Edition

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.

Multiple Generations In Today’S Workplace, Nicole Ritter

Best Integrated Writing

Nicole Ritter explores how to manage differences between Traditionalists, Baby Boomers, Generation X’ers, and Millennials in the workplace in this essay written for MGT 3110: Business Ethics & Leadership Development, taught by Mrs. Donna Back at Wright State University.

A Review Of Anatomical Presentation And Treatment In True Hermaphroditism, Jodie Heier

Best Integrated Writing

Jodie Heier studies genetic and hormonal contributors to gender identity in hermaphroditism in this essay written for PSY 4950: Sexuality and Endocrinology Capstone, taught by Dr. Patricia Schiml at Wright State University.