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Yale Medicine Thesis Digital Library

Theses/Dissertations

1971

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Full-Text Articles in Medicine and Health Sciences

An Examination Of The Relationships Between Catatonia And Manic-Depressive Disease, Michael Piercey Apr 1971

An Examination Of The Relationships Between Catatonia And Manic-Depressive Disease, Michael Piercey

Yale Medicine Thesis Digital Library

The abstract for this thesis is unavailable at the moment.


Resistance To Aqueous Outflow In The Rhesus Monkey Eye; Anatomic And Physiologic Studies In Vitro, Walter Peterson Jan 1971

Resistance To Aqueous Outflow In The Rhesus Monkey Eye; Anatomic And Physiologic Studies In Vitro, Walter Peterson

Yale Medicine Thesis Digital Library

Perfusion studies carried out in 50 enucleated normal Rhesus eyes suggested that the trabecular meshwork is responsible for 60-65% of the resistance to aqueous outflow, that aqueous outflow pathways in the inner 1/3 to 1/2 of the sclera are responsible for about 25%, that pathways in the outer 1/2 to 2/3 of the sclera account for 10-15%, and that more distal path ways account for very little, if any resistance. An initial opening into Schlemm's canal increased the facility of outflow proportionally much more than did subsequent extension of the incision. Mean facility of aqueous outflow was found to be …


Radiation Induced Changes In Pulmonary Perfusion In Rabbits, Sten Börje Löfgren Jan 1971

Radiation Induced Changes In Pulmonary Perfusion In Rabbits, Sten Börje Löfgren

Yale Medicine Thesis Digital Library

No abstract provided.


Regional Distribution Of 5-Methyltetrahydrofolate Dependent Dopamine-N-Methyl Transferase In Rat Brain And Its Presence In Human Brain, Douglas A. Berv Jan 1971

Regional Distribution Of 5-Methyltetrahydrofolate Dependent Dopamine-N-Methyl Transferase In Rat Brain And Its Presence In Human Brain, Douglas A. Berv

Yale Medicine Thesis Digital Library

Since the introduction of the hypothesis that abnormal transmethylation of biogenic amines may be associated with mental illness, transmethylation processes have been shown to be important in the production of biologically active amine derivatives. Laduron has shown that dopamine can be N-methylated with an enzyme from rat brain that requires 5-methyltetrahydrofolic acid (5MTHF ) as a methyl donor. This study shows that the methylation reaction which produces epinine from dopamine is greatest with supernatant from homogenized caudate lobe as compared to the cerebellum, hippocampus, cortex, and raphe nucleus: the brains of male rats were dissected and homogenized, the supernatant was …