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Association Between Alcohol Consumption And Both Osteoporotic Fracture And Bone Density, Karina M. Berg, Hillary V. Kunins, Jeffrey L. Jackson, Shadi Nahvi, Amina Chaudhry, Kenneth A. Harris Jr., Rubina Malik, Julia H. Arnsten
Association Between Alcohol Consumption And Both Osteoporotic Fracture And Bone Density, Karina M. Berg, Hillary V. Kunins, Jeffrey L. Jackson, Shadi Nahvi, Amina Chaudhry, Kenneth A. Harris Jr., Rubina Malik, Julia H. Arnsten
Uniformed Services University of the Health Sciences
OBJECTIVE: Alcoholism is a risk factor for osteoporotic fractures and low bone density, but the effects of moderate alcohol consumption on bone are unknown. We performed a systematic review and metaanalysis to assess the associations between alcohol consumption and osteoporotic fractures, bone density and bone density loss over time, bone response to estrogen replacement, and bone remodeling.
METHODS: MEDLINE, Current Contents, PsychINFO, and Cochrane Libraries were searched for studies published before May 14, 2007. We assessed quality using the internal validity criteria of the US Preventive Services Task Force.
RESULTS: We pooled effect sizes for 2 specific outcomes (hip fracture …