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Full-Text Articles in Medicine and Health Sciences
Affect Identification And Interpersonal Skills: An In-Depth Evaluation Of Social Cognition In Schizophrenia, Griffin Pollock Sutton
Affect Identification And Interpersonal Skills: An In-Depth Evaluation Of Social Cognition In Schizophrenia, Griffin Pollock Sutton
UNLV Theses, Dissertations, Professional Papers, and Capstones
The presence of deficits in various sub-domains of social cognition has been investigated to a degree in individuals with schizophrenia. Some of the most commonly researched and documented deficits have included impairments in the identification of affect portrayed in faces. Research has indicated that the performance of individuals with schizophrenia on such tasks is generally impaired as compared to normal controls. However, some have questioned the generalizability of such findings to real-world situations, as day-to-day interactions generally necessitate a constant, fluid assessment of the thoughts and feelings of others and are rarely, if ever, limited to still images of others. …
An Investigation Of The Role Of Gabab Ligands On Cued And Contextual Fear Conditioning, Chelcie F. Heaney
An Investigation Of The Role Of Gabab Ligands On Cued And Contextual Fear Conditioning, Chelcie F. Heaney
UNLV Theses, Dissertations, Professional Papers, and Capstones
GABA is the primary inhibitory neurotransmitter in the brain and mediates several processes, including learning and memory. Activating or inhibiting GABA receptors allows for the examination of the effects of altered GABAergic signaling on these processes. The two main receptors, GABAA and GABAB, each have a different mechanism of action when activated, thus they may contribute differentially to learning and memory. The metabotropic GABAB receptor responds with the activation of several intracellular signaling cascades, which provide long-lasting inhibitory effects that primarily mediate network function. Conversely, the GABAA receptor is an ion channel that contributes more immediate inhibitory effects through the …