Medicine and Health Sciences Commons^™

The Joint Effects Of Cognitive Function And Sedentary Time On Mortality Risk In Older Adults: 2011-2014 Nhanes, Sarah A. Wilson

UNF Graduate Theses and Dissertations

Background: Examining the joint effects of cognitive function (CF) and sedentary time (ST) may provide insight into the complex mechanisms underlying mortality risk within older adults. This study examines the joint effects of CF and ST on mortality risk in older adults.

Methods: Sample included 2,230 older adults (≥ 60 years of age) participants in the 2011-2014 National Health and Nutrition Examination Survey. The Digit Symbol Substitution Test (DSST), Consortium to Establish a Registry for Alzheimer's Disease (CERAD) subtests, and Animal Fluency (AF) were used to assess CF. Average daily sitting and television time represented ST. Quartiles of CF and …

Sleep, Sedentary Time, And Physical Activity In Heart Failure Subtypes: Multi-Ethnic Study Of Atherosclerosis (Mesa), Demi M. Nott

UNF Graduate Theses and Dissertations

INTRODUCTION: Previous studies have examined the associations between physical activity (PA), sedentary time (ST), and sleep on the risk of heart failure (HF). The primary aim of this study was to examine PA, ST, and sleep quality (SQ) in those diagnosed with preserved ejection fraction HF (HFpEF) and reduced ejection fraction HF (HFrEF). The secondary aim of this study was to examine these relationships in those with and without HF, independent of sub-type.

METHODS: The Multi-Ethnic Study of Atherosclerosis (MESA) collected data from 6,814 adults from a diversified cohort who range in age from 45 to 84. Subjects were classified …

Examining Potential Causal Associations Of Sedentary Time And Physical Activity With Heart Failure Using Subjective And Objective Measures: A Mendelian Randomization Analysis, Jessica Geller

UNF Graduate Theses and Dissertations

Purpose: The objective of this study was to assess the causal relationship between both subjectively and objectively measured sedentary time (ST) and physical activity (PA) with heart failure (HF) risk, utilizing Mendelian Randomization (MR) approach.

Methods: The present MR used genetic instruments identified for self-reported ST and PA extracted from 51 genome wide association studies (GWAS), encompassing data from 703,901 individuals. The GWAS identified 89 independent single nucleotide polymorphisms (SNPs) associated with leisure screen time. Eleven loci were reported to be associated with moderate to vigorous physical activity (MVPA). From another GWAS examining accelerometer-based activities, three loci were found to …

Association Between Objectively-Measured Sedentary Time And Self-Reported Prescription Medication Use Among Adults: A Pilot Study, Ciarra Ashley Boyne

UNF Graduate Theses and Dissertations

BACKGROUND: Prescription medication use and extended sedentary time are independently related to poor health outcomes (e.g., diabetes, metabolic syndrome, mortality). Historically, survey methods have been used to obtain estimates of total sedentary time (ST), however, recent use of accelerometers avoids self-report bias and affords more characteristics of ST that may be factors in health outcomes (e.g., frequency and duration of sedentary bouts). The aims of this pilot study were to 1) examine the association between objectively measured ST via accelerometers and self-reported prescription medication use in adults and 2) examine the independent association of sedentary bout length and frequency with …