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Full-Text Articles in Medicine and Health Sciences
The Role Of Il-6 And Osteoprotegerin In Bone Metabolism In Patients With Graves' Disease, Tülay Omma, Çi̇ğdem Yücel, Erdi̇m Sertoğlu, Sevde Nur Firat, Cavi̇t Çulha, Taner Özgürtaş
The Role Of Il-6 And Osteoprotegerin In Bone Metabolism In Patients With Graves' Disease, Tülay Omma, Çi̇ğdem Yücel, Erdi̇m Sertoğlu, Sevde Nur Firat, Cavi̇t Çulha, Taner Özgürtaş
Turkish Journal of Medical Sciences
Background/aim: Increased bone turnover is a hallmark of hyperthyroidism. The underlying factors of how thyroid hormones affect bone cells are still under the spotlight. Previous studies indicated serum osteoprotegerin (OPG), receptor activator of NF-kB ligand (RANKL), and interleukin-6 (IL-6) as mediators of the effect of thyroid hormones on bone metabolism. Ultimately, the present research aimed to examine the association of IL-6 with OPG and RANKL in patients with hyperthyroidism. Materials and methods: We carried out this study with 39 newly diagnosed and untreated Graves' patients and 43 healthy controls. In addition to routine tests, we measured serum OPG, RANKL, and …
Low Immunity Against Vaccine Preventable Diseases In Turkish Hiv Cohort, Aslihan Candevi̇r, Feri̇t Kuşcu, Fi̇gen Yildirim, Süheyla Kömür, Gönül Çi̇çek Şentürk, Ayşe Seza İnal, Fatma Eser, Sali̇h Çeti̇ner, Behi̇ce Kurtaran, Yeşi̇m Taşova
Low Immunity Against Vaccine Preventable Diseases In Turkish Hiv Cohort, Aslihan Candevi̇r, Feri̇t Kuşcu, Fi̇gen Yildirim, Süheyla Kömür, Gönül Çi̇çek Şentürk, Ayşe Seza İnal, Fatma Eser, Sali̇h Çeti̇ner, Behi̇ce Kurtaran, Yeşi̇m Taşova
Turkish Journal of Medical Sciences
Background/aim: HIV infection increase the risk of serious disease resulting from common vaccine-preventable infections. Vaccinations are particularly important for HIV infected adults. We aimed to investigate the immunity rates against measles, mumps, rubella, hepatitis A, B, and tetanus in newly diagnosed HIV patients. Materials and methods: Patients who admitted to outpatient clinics of three centers with newly diagnosed HIV infection, between 1 January 2015 and 31 June 2017 were included. Measles, mumps, rubella, varicella zoster virus, hepatitis A, hepatitis B, and tetanus antibody levels were measured by commercial diagnostic kits. Demographical and laboratory data of the patients were recorded. Results: …
Lack Of Awareness Of Hepatitis B Screening And Vaccination In High-Risk Groups, Hati̇ce Yasemi̇n Balaban, Abdullah Tarik Aslan, Şefi̇ka Nur Ayar, Osman Dağ, Alpaslan Alp, Cem Şi̇mşek, Cavanşi̇r Vahabov, Tolga Yildirim, Hakan Göker, Yahya Büyükaşik, Hali̇s Şi̇mşek
Lack Of Awareness Of Hepatitis B Screening And Vaccination In High-Risk Groups, Hati̇ce Yasemi̇n Balaban, Abdullah Tarik Aslan, Şefi̇ka Nur Ayar, Osman Dağ, Alpaslan Alp, Cem Şi̇mşek, Cavanşi̇r Vahabov, Tolga Yildirim, Hakan Göker, Yahya Büyükaşik, Hali̇s Şi̇mşek
Turkish Journal of Medical Sciences
Background/aim: Hepatitis B virus (HBV) vaccination rates are insufficient in high-risk patients worldwide. This study aimed to investigate the screening, immunization, and vaccination rates in three high-risk groups for HBV infection: allogeneic hematopoietic stem cell transplantation (AHSCT), renal transplantation (RT), and chronic hepatitis C (CHC) groups. Materials and methods: The serological data of consecutive patients between 2014 and 2019 were reviewed using the hospital database. Results: The HBV screening rates were 100.0%, 90.4%, and 82.4% in the AHSCT, CHC, and RT groups, respectively (p = 0.003). The immunization rates against HBV through either previous exposure or vaccination were 79.5%, 71.7%, …
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Evaluation Of Tetanus Antibody Levels In Adults In Yozgat, Turkey, Çi̇ğdem Kader, Mehmet Balci, Ayşe Erbay
Turkish Journal of Medical Sciences
Background/aim: To assess the immune status against tetanus in relation to self-declared vaccination status among an adult population in Yozgat, Turkey. Methods: Questionnaires and blood specimens were collected from 267 individuals over 18 years of age in Yozgat, Turkey. Antitetanus antibodies were determined quantitatively by enzyme-linked immunosorbent assay. Results: Among the 267 subjects (mean age 43.4 ± 15.6; male:female, 133:134) 168 (62.9%) had protective level of tetanus antibody titers. There was a characteristic distribution of the tetanus antibody titers in different age groups as it dropped with increasing age. Protective immunity was obtained in 74.1% of urban and 47.9% of …