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Full-Text Articles in Medicine and Health Sciences
Can We Turn Off The “Covid-Biting-Tail” Inflammation?, Valentina Giudice, Amelia Filippelli, Carmine Selleri
Can We Turn Off The “Covid-Biting-Tail” Inflammation?, Valentina Giudice, Amelia Filippelli, Carmine Selleri
Translational Medicine @ UniSa
To date, SARS-CoV-2 has infected more than 32 million people, and 30% of cases needs intensive care treatment for severe Covid-19 and related acute respiratory distress syndrome (ARDS). Despite medical efforts, mortality rate is still high, and no specific therapies have been outlined yet. Preliminary evidence from case reports and clinical trials using anti-inflammatory and anti-complement drugs shows a deep and overwhelmed inter-play between adaptive and immune responses triggered by SARS-CoV-2 infection. Therefore, a combinatorial therapeutic strategy targeting both inflammation and immune system might more efficiently stop this inflammatory loop and prevent the development of ARDS.
The Many Faces Of Covid-19: Organizing Pneumonia (Op) Pattern Hrct Features, Gaetano Rea
The Many Faces Of Covid-19: Organizing Pneumonia (Op) Pattern Hrct Features, Gaetano Rea
Translational Medicine @ UniSa
Covid-19 (coronavirus disease 2019) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On 30 January 2020 the World Health Organization (WHO) declared that the outbreak of Covid-19 realizes a public health emergency of international concern. Because of the primary involvement of the respiratory system, chest CT is strongly recommended in suspected Covid-19 cases, for both initial and follow-up. We present the case of a Covid-19 patient, a 57-year-old man, with a typical HRCT course of OP reaction.