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Full-Text Articles in Medicine and Health Sciences
Proliferative Index And Microvessel Density As Potential Prognostic Markers Of Canine Oral Malignant Melanomas, Nan Choisunirachon, Yuiko Tanaka, Kohei Saeki, Nobuo Sasaki, Ryohei Nishimura, Takayuki Nakagawa
Proliferative Index And Microvessel Density As Potential Prognostic Markers Of Canine Oral Malignant Melanomas, Nan Choisunirachon, Yuiko Tanaka, Kohei Saeki, Nobuo Sasaki, Ryohei Nishimura, Takayuki Nakagawa
The Thai Journal of Veterinary Medicine
Several reports have indicated the prognostic significance of the proliferative index (PI) and microvessel density (MVD) in canine oral malignant melanomas (MM). However, a correlation between the PI and MVD of oral MM in dogs has never been elucidated. Here, we evaluated the expression of Ki-67 and CD31 using double immunofluorescence staining to investigate the correlation of PI with MVD in 37 spontaneous canine oral MMs. No correlation was found between the MVD and PI values or between those and any clinicopathologic findings. However, a correlation was found between the PI value and both clinical stage (p = 0.0453) and …
Retrospective Study Of Computed Tomographic Characterization Of Canine Oral Malignant Melanoma In 24 Dogs, Nan Choisunirachon, Lee-Shuan Lin, Yuiko Tanaka, Kohei Saeki, Reina Fujiwara, Ryohei Nishimura, Takayuki Nakagawa
Retrospective Study Of Computed Tomographic Characterization Of Canine Oral Malignant Melanoma In 24 Dogs, Nan Choisunirachon, Lee-Shuan Lin, Yuiko Tanaka, Kohei Saeki, Reina Fujiwara, Ryohei Nishimura, Takayuki Nakagawa
The Thai Journal of Veterinary Medicine
Clinical and computed tomographic (CT) information from 24 histopathological diagnosed canine oral malignant melanomas (MMs) was retrospectively investigated. The CT appearance on canine oral MM from each patient was evaluated, including both bone and soft tissue windows and pre- and post-contrast enhancement. Among the 24 dogs, canine oral MM was highly presented in small breeds, especially in miniature dachshunds older than 10 years. The gingiva was the most commonly affected site, followed by palatine, mucosal, and lingual areas. The location of the primary tumor in the oral arcade was statistically significant associated with bone invasion such as osteolysis. Canine oral …