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Full-Text Articles in Medicine and Health Sciences

Rna Interference Targeting Glucose-Regulated-Protein 78 Induces Hepg2 Cell Apoptosis, Brittany Blackman Dec 2013

Rna Interference Targeting Glucose-Regulated-Protein 78 Induces Hepg2 Cell Apoptosis, Brittany Blackman

Seton Hall University Dissertations and Theses (ETDs)

Cancer is a complex genetic disease that is driven by genetic mutations resulting in chronic, inappropriate cell proliferation. Many current cancer therapies lack specificity towards tumor tissues, ultimately leading to adverse side effects and limited clinical efficacy. Recently, selective cancer cell therapy has examined a well-characterized cell surface marker that is preferentially expressed on tumor cells. The over-expression of an endoplasmic reticulum chaperone protein, 78-kDa glucose-regulated-protein (GRP78), has been observed on the surface of cancer cells, but not on normal tissues. By selectively targeting GRP78 with short-interfering RNA (siRNA), potent GRP78 silencing is anticipated by the RNA interference (RNAi) pathway. …


The Effect Of Mcconnell Shoulder Taping On Shoulder Muscle Emg And Shoulder Torque Productions In Subjects With Anterior Shoulder Instability, Robin H. Stoller Aug 2013

The Effect Of Mcconnell Shoulder Taping On Shoulder Muscle Emg And Shoulder Torque Productions In Subjects With Anterior Shoulder Instability, Robin H. Stoller

Seton Hall University Dissertations and Theses (ETDs)

Introduction: Anterior shoulder instability (ASI), a common clinical problem, causes significant functional impairments. Despite little evidence to support its use, rehabilitation directed at the unstable glenohumeral joint often includes McConnell shoulder taping. This taping technique consists of a base layer of tape followed by application of a rigid strapping tape (corrective) to restrain excessive translation of the humeral head. The aims of this study were to determine the effects of McConnell shoulder taping on EMG amplitude of ten shoulder muscles and on shoulder joint peak torque between three conditions: no tape and base tape alone; no tape and McConnell tape …


Learning Styles, Critical Thinking Aptitudes, And Immersion Learning In Physician Assistant Students, Nora Lowy May 2013

Learning Styles, Critical Thinking Aptitudes, And Immersion Learning In Physician Assistant Students, Nora Lowy

Seton Hall University Dissertations and Theses (ETDs)

The changes in healthcare delivery systems and the global burden of disease along with the overwhelming corpus of new knowledge call for a re-evaluation of the educational process of health profession programs. The focus on how best to optimize the learning process necessitates an acknowledgement of the roles of learning styles and critical thinking aptitudes. It also requires attention to the learning experiences and how these, in turn, affect development of both the styles and aptitudes. A sample of 137 Physician Assistant students was recruited to complete a learning style inventory, the Gregorc Style Delineator, and a critical thinking aptitude …


Activation And Suppression Of The Innate Immune System: Effects On Alcohol Intake, Marjorie Levinstein May 2013

Activation And Suppression Of The Innate Immune System: Effects On Alcohol Intake, Marjorie Levinstein

Seton Hall University Dissertations and Theses (ETDs)

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An Evidence-Based Approach To Feeding The Late Preterm Infant, Diane Mcclure Apr 2013

An Evidence-Based Approach To Feeding The Late Preterm Infant, Diane Mcclure

Seton Hall University Dissertations and Theses (ETDs)

No abstract provided.


Facilitating Social Integration For People With Severe Mental Illness, Sheila Linz Mar 2013

Facilitating Social Integration For People With Severe Mental Illness, Sheila Linz

Seton Hall University Dissertations and Theses (ETDs)

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The Relationship Between Intergenerational Solidarity And Medication Adherence In Community Dwelling Elders, Connie Rutan Kartoz Mar 2013

The Relationship Between Intergenerational Solidarity And Medication Adherence In Community Dwelling Elders, Connie Rutan Kartoz

Seton Hall University Dissertations and Theses (ETDs)

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The Experiences Of Indian Nurses In America, Munira Wells Mar 2013

The Experiences Of Indian Nurses In America, Munira Wells

Seton Hall University Dissertations and Theses (ETDs)

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The Relationship Of Perceived Trust And Perceived Stress Among Pregnant Women Receiving Care From A Certified Nurse Midwife, Maria Torchia Logrippo Mar 2013

The Relationship Of Perceived Trust And Perceived Stress Among Pregnant Women Receiving Care From A Certified Nurse Midwife, Maria Torchia Logrippo

Seton Hall University Dissertations and Theses (ETDs)

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The Ties That Bind: The Relationships Between And Among Registered Nurses' Clinical Experience, Clinical Decision-Making Processes, And Nursing Practice Issues Related To Physical Restraint Use With Attitudes Toward The Use Of Physical Restraints In The Critical Care Environment, Kristi Stinson Mar 2013

The Ties That Bind: The Relationships Between And Among Registered Nurses' Clinical Experience, Clinical Decision-Making Processes, And Nursing Practice Issues Related To Physical Restraint Use With Attitudes Toward The Use Of Physical Restraints In The Critical Care Environment, Kristi Stinson

Seton Hall University Dissertations and Theses (ETDs)

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Critical Thinking Skills And Medical Dosimetry Education, Anne W. Greener Mar 2013

Critical Thinking Skills And Medical Dosimetry Education, Anne W. Greener

Seton Hall University Dissertations and Theses (ETDs)

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Exploring Knowledge, Attitudes And Practices Of Registered Nurses Regarding The Spread Of Nosocomial Infections, Eunice W. Kamunge Jan 2013

Exploring Knowledge, Attitudes And Practices Of Registered Nurses Regarding The Spread Of Nosocomial Infections, Eunice W. Kamunge

Seton Hall University Dissertations and Theses (ETDs)

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Examination Of The Impact Of Race-Related Stress And Culture-Specific Coping On Burnout And Compassion Fatigue In Black Nursing Assistants, Marika A. Maris Jan 2013

Examination Of The Impact Of Race-Related Stress And Culture-Specific Coping On Burnout And Compassion Fatigue In Black Nursing Assistants, Marika A. Maris

Seton Hall University Dissertations and Theses (ETDs)

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The Prevalence Of Burnout Among Chiropractic Practitioners, Shawn P. Williams Jan 2013

The Prevalence Of Burnout Among Chiropractic Practitioners, Shawn P. Williams

Seton Hall University Dissertations and Theses (ETDs)

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The Correlation Of Repeat Sprint Measures To Predicted Vo2 In Recreationally Active Males, Matthew R. Miltenberger Jan 2013

The Correlation Of Repeat Sprint Measures To Predicted Vo2 In Recreationally Active Males, Matthew R. Miltenberger

Seton Hall University Dissertations and Theses (ETDs)

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Nurse Manager Caring And Workplace Bullying In Nursing : The Relationship Between Staff Nurses' Perceptions Of Nurse Manager Caring Behaviors And Their Perception Of Exposure To Workplace Bullying Within Multiple Healthcare Settings, Lynda Diana Olender Jan 2013

Nurse Manager Caring And Workplace Bullying In Nursing : The Relationship Between Staff Nurses' Perceptions Of Nurse Manager Caring Behaviors And Their Perception Of Exposure To Workplace Bullying Within Multiple Healthcare Settings, Lynda Diana Olender

Seton Hall University Dissertations and Theses (ETDs)

This study examined the relationship between staff nurses’ perception of nurse manager caring behaviors and their perceived exposure to workplace bullying within multiple healthcare settings. It was based on the theoretical position that caring promotes reciprocal caring and healing for each other and for the larger universe as informed by Watson’s theory of human caring (1979, 2006, 2008). Results indicated a statistically significant, negative, linear relationship between the CFS-CM and the NAQ-R (r = -.534, p < .001), meaning that as staff nurses’ perceptions of their nurse manager caring increased, their perception of exposure to negative acts (meeting the definition of workplace bullying) significantly decreased. The sample consisted of primarily older, more experienced, staff nurses who worked 10 years or longer within their work environment. Data analysis also revealed that staff nurses who were females and those who worked in Medical/Surgical settings were significantly more likely to perceive their managers as caring (p < .05 respectively) and that a high workload significantly influenced the staff nurses perception of exposure to workplace bullying (p < .05). In view of the predicted nursing shortages as baby-boomer nurses retire at the same time the demand for health care is rising (AACN, 2009), these findings highlight the importance of caring leadership for the health and availability of nurses at the bedside, and may lead to shifting work priorities for nurse managers. Study findings may also foster the design and implementation of a caring curriculum and caring competencies applicable for the nurse managers’ role either within nursing academic or clinical settings.