Medicine and Health Sciences Commons^™

Buprenorphine Versus Methadone For Opioid Use Disorder, Ben Devries

Physician Assistant Scholarly Project Posters

The purpose of this literature review is to analyze the use of Buprenorphine and Methadone for the treatment of opioid use disorder. Comparison of overall safety, efficacy, morbidity and mortality between the two treatment options is accomplished throughout this article. The literature review was performed using databases: PubMed, Clinical Key, Cochane and Uptodate. Results were limited to studies completed within the past 7 years. Methadone has been the treatment mainstay of opioid use disorder for decades. Buprenorphine has increased in popularity and prevalence for treatment of opioid use disorder, especially after receiving FDA approval for such use in 2002. Several …

Mat Effectiveness For Oxycodone Vs Heroin In Opioid Use Disorders, Casey Myklebust

Physician Assistant Scholarly Project Posters

Opioid use disorder is a major epidemic in the United States. • Rural areas suffer the most with limited resources available for treatments options. • A limited number of providers participate in MAT programs due to a negative stigma. • Project Echo was developed to spread awareness and information about MAT to educate providers and healthcare facilities about the needs of opioid use disorder patients that are not being met. • Buprenorphine, naltrexone, and methadone are the FDA approved medications to assist in MAT. • Medication assisted treatment is a long-term commitment to successfully maintain sobriety. • Medication alone is …

A Comparison Of Pharmacologic Interventions In Pregnant Women With Opioid Use Disorder, Catherine K. Bopp

Physician Assistant Scholarly Project Posters

The purpose of this research and systematic literature review is to determine which pharmacotherapeutic agent, methadone or buprenorphine, leads to better outcomes in cases of pregnant mothers with opioid use disorder (OUD).

Outcomes considered are maternal compliance, neonatal abstinence syndrome severity, and neonatal length of hospital stay. In the review, PubMed, Clinical Key, Cochrane Database of Systematic Reviews, and DynaMed Plus were searched. Key terms searched were “methadone, buprenorphine, pregnancy”, “opioids, pregnancy”, “neonatal abstinence syndrome” and “medication assisted treatment, pregnancy”. Several studies were excluded, as their study population was not specified to have diagnosed OUD in pregnancy. The drawbacks to …